N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. (Q37276819)

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13 March 2020

title

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A (English)

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13 March 2020

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1

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Kwok Ho Lam

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13 March 2020

Daniel Stern

5

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13 March 2020

Kay Perry

7

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13 March 2020

Markus Kalkum

8

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13 March 2020

Andreas Rummel

9

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13 March 2020

Rongsheng Jin

11

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13 March 2020

author name string

Sicai Zhang

2

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13 March 2020

Stefan Mahrhold

3

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13 March 2020

Karine Bagramyan

6

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13 March 2020

Min Dong

10

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13 March 2020

publication date

13 June 2016

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Nature Structural & Molecular Biology

13 March 2020

published in

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volume

23

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issue

7

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13 March 2020

page(s)

656-662

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https://scigraph.springernature.com/pub.10.1038/nsmb.3245

13 March 2020

exact match

0 references

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Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons.

6 September 2017

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Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors

6 September 2017

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6 September 2017

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6 September 2017

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Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F

6 September 2017

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Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.

6 September 2017

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Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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SV2 is the protein receptor for botulinum neurotoxin A.

6 September 2017

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Botulinum Neurotoxins: Qualitative and Quantitative Analysis Using the Mouse Phrenic Nerve Hemidiaphragm Assay (MPN)

14 September 2017

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Draft Genome Sequence of Bivalent Clostridium botulinum Strain IBCA10-7060, Encoding Botulinum Neurotoxin B and a New FA Mosaic Type

26 June 2018

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26 June 2018

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Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor

3 September 2018

1 reference

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3 September 2018

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https://api.crossref.org/works/10.1038%2FNSMB.3245

Improving biosensor analysis

31 March 2020

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Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27294781

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.3245

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27294781%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27294781%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference