Disposition of drugs in block copolymer micelle delivery systems: from discovery to recovery (Q37265495)

19 August 2017

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title

Disposition of drugs in block copolymer micelle delivery systems: from discovery to recovery (English)

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19 August 2017

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Hamidreza Montazeri Aliabadi

1

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19 August 2017

Mostafa Shahin

2

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19 August 2017

Dion R Brocks

3

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19 August 2017

Afsaneh Lavasanifar

4

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19 August 2017

1 January 2008

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Clinical Pharmacokinetics

19 August 2017

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19 August 2017

47

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19 August 2017

10

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19 August 2017

619-634

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https://scigraph.springernature.com/pub.10.2165/00003088-200847100-00001

19 August 2017

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Pharmacokinetic and local tissue disposition studies of naproxen-following topical and systemic administration in dogs and rats

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Fundamental relationships between the composition of pluronic block copolymers and their hypersensitization effect in MDR cancer cells

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Micelles self-assembled from poly(ethylene oxide)-block-poly(N-hexyl stearate L-aspartamide) by a solvent evaporation method: effect on the solubilization and haemolytic activity of amphotericin B.

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Tricaprylin microemulsion for oral delivery of low molecular weight heparin conjugates

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Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation.

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Liposomes. Opportunities in drug delivery

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Mixed polymer micelles of amphiphilic and cationic copolymers for delivery of antisense oligonucleotides.

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Exploiting the vitamin B12 pathway to enhance oral drug delivery via polymeric micelles

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Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P123.

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Ophthalmic vehicles containing polymer-solubilized tropicamide: "in vitro/in vivo" evaluation

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Supramolecular assemblies based on copolymers of PEG600 and functionalized aromatic diesters for drug delivery applications

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Ketorolac entrapped in polymeric micelles: preparation, characterisation and ocular anti-inflammatory studies

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Polymeric micelles for drug delivery

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In situ gelling xyloglucan formulations for sustained release ocular delivery of pilocarpine hydrochloride

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Ocular permeability of pirenzepine hydrochloride enhanced by methoxy poly(ethylene glycol)-poly(D, L-lactide) block copolymer

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Amphiphilic block copolymers for drug delivery

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Incorporation and release behavior of hydrophobic drug in functionalized poly(D,L-lactide)-block-poly(ethylene oxide) micelles.

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Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel

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12 December 2020

Engineering polysaccharide-based polymeric micelles to enhance permeability of cyclosporin A across Caco-2 cells

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12 December 2020

Polymeric micellar paclitaxel phosphorylates Bcl-2 and induces apoptotic regression of androgen-independent LNCaP prostate tumors.

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12 December 2020

Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies

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12 December 2020

Polymeric micelles for drug targeting

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12 December 2020

In vivo pharmacokinetic and tissue distribution studies in mice of alternative formulations for local and systemic delivery of Paclitaxel: gel, film, prodrug, liposomes and micelles

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12 December 2020

Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance

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12 December 2020

Structure and design of polymeric surfactant-based drug delivery systems

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12 December 2020

Block copolymers as drug carriers

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12 December 2020

Large liposomes containing ganglioside GM1 accumulate effectively in spleen

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12 December 2020

Toxicity and antitumor activity against solid tumors of micelle-forming polymeric anticancer drug and its extremely long circulation in blood

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12 December 2020

Enhanced efficacy by percutaneous absorption of piroxicam from the poloxamer gel in rats.

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12 December 2020

Influence of emulsion droplet surface charge on indomethacin ocular tissue distribution

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12 December 2020

NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

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12 December 2020

Ultrasound-triggered drug targeting of tumors in vitro and in vivo.

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12 December 2020

Hydrotropic polymeric micelles for enhanced paclitaxel solubility: in vitro and in vivo characterization

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12 December 2020

Transdermal delivery of insulin from poloxamer gel: ex vivo and in vivo skin permeation studies in rat using iontophoresis and chemical enhancers

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Investigation of lectin-modified insulin liposomes as carriers for oral administration

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12 December 2020

Drug delivery systems: entering the mainstream

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12 December 2020

Evaluation of bioadhesive potential and intestinal transport of pegylated poly(anhydride) nanoparticles.

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12 December 2020

Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer

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12 December 2020

Clonazepam release from poly(DL-lactide-co-glycolide) nanoparticles prepared by dialysis method

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12 December 2020

A novel use of an in vitro method to predict the in vivo stability of block copolymer based nano-containers

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12 December 2020

In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein

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12 December 2020

Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors.

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12 December 2020

Polymeric micelles for delivery of poorly water-soluble compounds

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12 December 2020

Thermosensitive sol-gel reversible hydrogels

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12 December 2020

Liposomes as an ocular delivery system for acetazolamide: in vitro and in vivo studies.

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12 December 2020

In vivo fate of unimers and micelles of a poly(ethylene glycol)-block-poly(caprolactone) copolymer in mice following intravenous administration

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12 December 2020

Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats

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12 December 2020

The immune response and protective efficacy of vaccination with oral microparticle Aeromonas sobria vaccine in mice

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12 December 2020

Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer.

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12 December 2020

A mixed polymeric micellar formulation of itraconazole: Characteristics, toxicity and pharmacokinetics

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12 December 2020

Bioavailability of tobramycin after oral delivery in FVB mice using CRL-1605 copolymer, an inhibitor of P-glycoprotein

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12 December 2020

Self-assembling PEG-p(CL-co-TMC) copolymers for oral delivery of poorly water-soluble drugs: a case study with risperidone

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12 December 2020

Hypersensitizing effect of pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells

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12 December 2020

Diblock copolymer nanoparticles for drug delivery

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12 December 2020

Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer

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12 December 2020

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

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12 December 2020

In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a pluronic lecithin organogel vehicle containing fish oil

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12 December 2020

Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies

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12 December 2020

Methoxy poly(ethylene glycol) and epsilon-caprolactone amphiphilic block copolymeric micelle containing indomethacin. II. Micelle formation and drug release behaviours

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12 December 2020

An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties

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12 December 2020

Enhanced transdermal delivery of pranoprofen from the bioadhesive gels.

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12 December 2020

In vivo skin permeation of sodium naproxen formulated in pluronic F-127 gels: effect of Azone and Transcutol

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12 December 2020

In vivo gene delivery into ocular tissues by eye drops of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) polymeric micelles

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12 December 2020

NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel

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12 December 2020

Increased partitioning of pilocarpine to the oily phase of submicron emulsion does not result in improved ocular bioavailability

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12 December 2020

Nonionic polymeric micelles for oral gene delivery in vivo

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12 December 2020

Preparation and drug loading of poly(ethylene glycol)-block-poly(epsilon-caprolactone) micelles through the evaporation of a cosolvent azeotrope

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12 December 2020

Block copolymer micelles for drug delivery: design, characterization and biological significance

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12 December 2020

Indomethacin-loaded methoxy poly(ethylene glycol)/ poly(epsilon-caprolactone) diblock copolymeric nanosphere: pharmacokinetic characteristics of indomethacin in the normal Sprague-Dawley rats.

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12 December 2020

Enhanced oral bioavailability of paclitaxel by coadministration of the P-glycoprotein inhibitor KR30031.

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12 December 2020

Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer.

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12 December 2020

Development of the polymer micelle carrier system for doxorubicin

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12 December 2020

Targeted polymeric micelles for delivery of poorly soluble drugs

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12 December 2020

Enhanced cellular accumulation of a P-glycoprotein substrate, rhodamine-123, by Caco-2 cells using low molecular weight methoxypolyethylene glycol-block-polycaprolactone diblock copolymers

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12 December 2020

Selective delivery of adriamycin to a solid tumor using a polymeric micelle carrier system.

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12 December 2020

Sustained-release tablets of indomethacin-loaded microcapsules: preparation, in vitro and in vivo characterization.

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12 December 2020

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy

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12 December 2020

The effects of pluronics block copolymers and Cremophor EL on intestinal lipoprotein processing and the potential link with P-glycoprotein in Caco-2 cells

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12 December 2020

An investigation of the antitumour activity and biodistribution of polymeric micellar paclitaxel

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12 December 2020

Investigation of pluronic and PEG-PE micelles as carriers of meso-tetraphenyl porphine for oral administration

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12 December 2020

Intestinal uptake and biodistribution of novel polymeric micelles after oral administration

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12 December 2020

Doxorubicin loaded pH-sensitive micelle targeting acidic extracellular pH of human ovarian A2780 tumor in mice

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12 December 2020

Distribution kinetics of a micelle-forming block copolymer Pluronic P85

1 reference

12 December 2020

Biodistribution of micelle-forming polymer-drug conjugates

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12 December 2020

Pharmaceutical evaluation of genistein-loaded pluronic micelles for oral delivery

1 reference

12 December 2020

A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation

1 reference

12 December 2020

Poly(ethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: improved hydrosolubility, stability and bioavailability of drugs

1 reference

12 December 2020

Gels and liposomes in optimized ocular drug delivery: studies on ciprofloxacin formulations

1 reference

12 December 2020

Gastrointestinal uptake of biodegradable microparticles: effect of particle size

1 reference

12 December 2020

Encapsulation of hydrophobic drugs in polymeric micelles through co-solvent evaporation: the effect of solvent composition on micellar properties and drug loading

1 reference

12 December 2020

Folate receptor targeted biodegradable polymeric doxorubicin micelles

1 reference

12 December 2020

Polymeric micelles - a new generation of colloidal drug carriers

1 reference

12 December 2020

Significantly improved oral uptake of amikacin in FVB mice in the presence of CRL-1605 copolymer.

1 reference

12 December 2020

Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin

1 reference

12 December 2020

Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells.

1 reference

12 December 2020

In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy

1 reference

12 December 2020

Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor.

1 reference

12 December 2020

Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers.

1 reference

12 December 2020

Pegylation: a novel process for modifying pharmacokinetics

1 reference

12 December 2020

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

1 reference

12 December 2020

The immune response and protective efficacy of oral alginate microparticle Aeromonas sobria vaccine in soft-shelled turtles (Trionyx sinensis).

1 reference

12 December 2020

Effects of pluronic block copolymers on drug absorption in Caco-2 cell monolayers

1 reference

12 December 2020

Enhanced oral paclitaxel bioavailability after administration of paclitaxel-loaded lipid nanocapsules

1 reference

12 December 2020

Relative bioavailability of ketoprofen 20% in a poloxamer-lecithin organogel.

1 reference

12 December 2020

Block copolymer micelles for the encapsulation and delivery of amphotericin B.

1 reference

12 December 2020

Liposomes with prolonged circulation times: factors affecting uptake by reticuloendothelial and other tissues

1 reference

12 December 2020

Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation

1 reference

12 December 2020

Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interaction with leuprolide

1 reference

12 December 2020

Eye drop delivery of nano-polymeric micelle formulated genes with cornea-specific promoters

1 reference

12 December 2020

An in vitro examination of the impact of polyethylene glycol 400, Pluronic P85, and vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine.

1 reference

12 December 2020

Transdermal timolol delivery from a Pluronic gel

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12 December 2020

Block copolymer micelles for delivery of gene and related compounds

1 reference

12 December 2020

Long-circulating (sterically stabilized) liposomes for targeted drug delivery

1 reference

12 December 2020

Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system

1 reference

12 December 2020

Poly(ethylene oxide)-block-poly(L-amino acid) micelles for drug delivery

1 reference

12 December 2020

Water-soluble block polycations as carriers for oligonucleotide delivery

1 reference

12 December 2020

Oil-in-water lipid emulsions: implications for parenteral and ocular delivering systems

1 reference

12 December 2020

Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles.

1 reference

12 December 2020

Poloxamer gel as vehicle for transdermal iontophoretic delivery of arginine vasopressin: evaluation of in vivo performance in rats

1 reference

12 December 2020

A lecithin-based microemulsion of rh-insulin with aprotinin for oral administration: Investigation of hypoglycemic effects in non-diabetic and STZ-induced diabetic rats

1 reference

12 December 2020

PEG-based micelles as carriers of contrast agents for different imaging modalities

1 reference

12 December 2020

Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice

1 reference

12 December 2020

Polymeric micelles for the solubilization and delivery of cyclosporine A: pharmacokinetics and biodistribution

1 reference

12 December 2020

Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery.

1 reference

12 December 2020

Clonazepam release from core-shell type nanoparticles in vitro

1 reference

12 December 2020

Cellulose acetate butyrate-pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA.

1 reference

12 December 2020

Discoidal niosome based controlled ocular delivery of timolol maleate

1 reference

12 December 2020

Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer

1 reference

12 December 2020

10.2165/00003088-200847100-00001

Identifiers

DOI

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Dimensions Publication ID

19 August 2017

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