DNA vaccination and gene therapy: optimization and delivery for cancer therapy (Q37259636)

19 August 2017

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title

DNA vaccination and gene therapy: optimization and delivery for cancer therapy (English)

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19 August 2017

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Angela M Bodles-Brakhop

series ordinal

1

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PubMed ID

18767956

19 August 2017

Ruxandra Draghia-Akli

series ordinal

2

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19 August 2017

1 September 2008

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Expert Review of Vaccines

19 August 2017

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19 August 2017

7

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19 August 2017

7

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19 August 2017

1085-1101

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Tumour immunity: effector response to tumour and role of the microenvironment

19 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Immunoregulatory T cells: role and potential as a target in malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

DNA vaccination against tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

DNA vaccines: precision tools for activating effective immunity against cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Carcinoembryonic antigen-based vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Perspectives on the development of a therapeutic HER-2 cancer vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Treatment of metastatic malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Current immunotherapeutic strategies in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Melanoma cancer vaccines and anti-tumor T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Optimization and delivery of plasmid DNA for vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Synthetic muscle promoters: activities exceeding naturally occurring regulatory sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Diverse plasmid DNA vectors by directed molecular evolution of cytomegalovirus promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Promoters influence the kinetics of transgene expression following adenovector gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Replication-competent retrovirus vectors for cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Potential of alphavirus vectors in the treatment of advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Cancer-specific activation of the survivin promoter and its potential use in gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Evaluation of tumor-specific promoter activities in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Double-blinded, Placebo-controlled plasmid GHRH trial for cancer-associated anemia in dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Long-term effects of plasmid-mediated growth hormone releasing hormone in dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Codon optimization of the HPV-16 E5 gene enhances protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

A synthetic E7 gene of human papillomavirus type 16 that yields enhanced expression of the protein in mammalian cells and is useful for DNA immunization studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Both antigen optimization and lysosomal targeting are required for enhanced anti-tumour protective immunity in a human papillomavirus E7-expressing animal tumour model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

A conditionally replicating adenovirus targeted to tumor cells through activated RAS/P-MAPK-selective mRNA stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Plasmid-based expression technology using growth hormone releasing hormone: a novel method for physiologically stimulating long-term growth hormone secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

TLR9 as a key receptor for the recognition of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

The role of CpG in DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

CpG motifs are efficient adjuvants for DNA cancer vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Effect of plasmid backbone modification by different human CpG motifs on the immunogenicity of DNA vaccine vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Arming parvoviruses with CpG motifs to improve their oncosuppressive capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Prophylactic naked DNA vaccination with the human vascular endothelial growth factor induces an anti-tumor response in C57Bl/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

CPG-7909 (PF-3512676, ProMune): toll-like receptor-9 agonist in cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Connective tissue growth factor linked to the E7 tumor antigen generates potent antitumor immune responses mediated by an antiapoptotic mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Adjuvanticity of plasmid DNA encoding cytokines fused to immunoglobulin Fc domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Enhancement of antitumour immunity by a novel chemotactic antigen DNA vaccine encoding chemokines and multiepitopes of prostate-tumour-associated antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

A MUC1/IL-18 DNA vaccine induces anti-tumor immunity and increased survival in MUC1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Interleukin-18 enhances Th1 immunity and tumor protection of a DNA vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

T-cell immunity generated by recombinant adenovirus vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Recent developments in the use of adenoviruses and immunotoxins in cancer gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Cancer gene therapy using adeno-associated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Adeno-associated virus vectors: potential applications for cancer gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

The state of the art of adeno-associated virus-based vectors in gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Targeted and shielded adenovectors for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Targeting lung cancer using an infectivity enhanced CXCR4-CRAd

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Radiation enhances adenoviral gene therapy in pancreatic cancer via activation of cytomegalovirus promoter and increased adenovirus uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Electroporation for targeted gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

In vivo electroporation for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Electrically-assisted nucleic acids delivery to tissues in vivo: where do we stand?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Water insoluble and soluble lipids for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Toxicity of cationic lipids and cationic polymers in gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Mannan-mediated gene delivery for cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Physical characterization and in vivo evaluation of poloxamer-based DNA vaccine formulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Sequence and time dependence of transfection efficiency of electrically-assisted gene delivery to tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

The effect of the histological properties of tumors on transfection efficiency of electrically assisted gene delivery to solid tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Enhancement of cellular immune response to a prostate cancer DNA vaccine by intradermal electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Ultrasound facilitates transduction of naked plasmid DNA into colon carcinoma cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Pulsed high-intensity focused ultrasound enhances systemic administration of naked DNA in squamous cell carcinoma model: initial experience.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

A phase I study of immunization using particle-mediated epidermal delivery of genes for gp100 and GM-CSF into uninvolved skin of melanoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Quadrivalent human papillomavirus recombinant vaccine: the first vaccine for cervical cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

A clinical development paradigm for cancer vaccines and related biologics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Prevention and treatment of cancer cachexia: new insights into an old problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Elements in the pathophysiology of diminished growth hormone (GH) secretion in aging humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Effects of chronic growth hormone and insulin-like growth factor 1 deficiency on osteoarthritis severity in rat knee joints.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Growth hormone releasing hormone plasmid supplementation, a potential treatment for cancer cachexia, does not increase tumor growth in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

DNA, but not protein vaccine based on mutated BORIS antigen significantly inhibits tumor growth and prolongs the survival of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Antibody and CD8+ T cell responses against HER2/neu required for tumor eradication after DNA immunization with a Flt-3 ligand fusion vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Enhancing DNA vaccine potency by combining a strategy to prolong dendritic cell life and intracellular targeting strategies with a strategy to boost CD4+ T cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

Efficacy of nonviral gene transfer in the canine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

A polyepitope DNA vaccine targeted to Her-2/ErbB-2 elicits a broad range of human and murine CTL effectors to protect against tumor challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.7.7.1085

10.1586/14760584.7.7.1085

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18767956