Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice (Q37254850)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23820820%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Silencing mutant ATXN3 expression resolves molecular phenotypes in SCA3 transgenic mice (English)

1 reference

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4 March 2020

6

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4 March 2020

author name string

Edgardo Rodríguez-Lebrón

1

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4 March 2020

Maria do Carmo Costa

2

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4 March 2020

Katiuska Luna-Cancalon

3

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4 March 2020

Therese M Peron

4

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4 March 2020

Svetlana Fischer

5

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4 March 2020

Beverly L Davidson

7

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4 March 2020

Henry L Paulson

8

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4 March 2020

publication date

3 July 2013

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4 March 2020

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4 March 2020

volume

21

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4 March 2020

issue

10

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4 March 2020

page(s)

1909-1918

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Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease

4 March 2020

cites work

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MicroRNAs shape the neuronal landscape

6 September 2017

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Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons

6 September 2017

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Toward understanding Machado-Joseph disease

6 September 2017

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Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

6 September 2017

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Early changes in cerebellar physiology accompany motor dysfunction in the polyglutamine disease spinocerebellar ataxia type 3

6 September 2017

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Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease

6 September 2017

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Splice isoform-specific suppression of the Cav2.1 variant underlying spinocerebellar ataxia type 6.

6 September 2017

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6 September 2017

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Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117.

6 September 2017

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6 September 2017

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Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease

6 September 2017

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Alterations of the microRNA network cause neurodegenerative disease.

6 September 2017

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Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs

6 September 2017

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Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo

6 September 2017

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6 September 2017

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RNA toxicity is a component of ataxin-3 degeneration in Drosophila

6 September 2017

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Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi

6 September 2017

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The role of site accessibility in microRNA target recognition

6 September 2017

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Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3808130

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

6 September 2017

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

6 September 2017

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The roles of proteolysis and nuclear localisation in the toxicity of the polyglutamine diseases. A review

6 September 2017

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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

6 September 2017

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Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3808130

The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.

14 September 2017

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14 September 2017

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14 September 2017

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28 September 2017

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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3 September 2018

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Target accessibility dictates the potency of human RISC

3 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23820820

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reversibility of symptoms in a conditional mouse model of spinocerebellar ataxia type 3

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2013.152

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release_bu2ddku4cbarzpui735ghmysiq

4 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bu2ddku4cbarzpui735ghmysiq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23820820%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference