Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity. (Q37254788)

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23 January 2020

title

Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity (English)

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23 January 2020

5

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23 January 2020

author name string

Jianhua Ju

1

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23 January 2020

Wenli Li

2

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23 January 2020

Qiuping Yuan

3

1 reference

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23 January 2020

Noel R Peters

4

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23 January 2020

Scott R Rajski

6

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23 January 2020

Hiroyuki Osada

7

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23 January 2020

Ben Shen

8

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23 January 2020

language of work or name

English

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publication date

1 April 2009

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23 January 2020

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23 January 2020

volume

11

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23 January 2020

issue

7

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23 January 2020

page(s)

1639-1642

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Characterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis

23 January 2020

cites work

1 reference

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Crystal Structures of Protein Phosphatase-1 Bound to Nodularin-R and Tautomycin: A Novel Scaffold for Structure-based Drug Design of Serine/Threonine Phosphatase Inhibitors

6 September 2017

1 reference

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Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis

6 September 2017

1 reference

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Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins

6 September 2017

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Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?

6 September 2017

1 reference

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Synthesis of specific protein phosphatase inhibitors, tautomycin and tautomycetin toward structure-activity relationship study

6 September 2017

1 reference

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Different moieties of tautomycin involved in protein phosphatase inhibition and induction of apoptosis.

6 September 2017

1 reference

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A model for binding of structurally diverse natural product inhibitors of protein phosphatases PP1 and PP2A.

26 June 2018

1 reference

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A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2707755

The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2707755

Tautomycetin is a novel and specific inhibitor of serine/threonine protein phosphatase type 1, PP1.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2707755

A new antibiotic, tautomycin

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19281218

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The structure of tautomycetin, a dialkylmaleic anhydride antibiotic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19281218

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/OL900293J

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19281218%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19281218%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference