Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin (Q37248577)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078692%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin (English)

1 reference

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23 February 2020

0 references

0 references

1 reference

6

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23 February 2020

Felix Yarovinsky

9

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23 February 2020

author name string

Megan Raetz

1

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23 February 2020

Alexey Kibardin

2

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23 February 2020

Carolyn R Sturge

3

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23 February 2020

Reed Pifer

4

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23 February 2020

Haiying Li

5

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23 February 2020

Keiko Ozato

7

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23 February 2020

Sergey Larin

8

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23 February 2020

language of work or name

English

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publication date

27 September 2013

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23 February 2020

published in

Journal of Immunology

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23 February 2020

volume

191

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23 February 2020

page(s)

4818-4827

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23 February 2020

issue

9

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UNC93B1 mediates differential trafficking of endosomal TLRs

23 February 2020

cites work

1 reference

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Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice

6 September 2017

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Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii

6 September 2017

1 reference

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Toxoplasma co-opts host cells it does not invade

6 September 2017

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TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification

6 September 2017

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CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites

6 September 2017

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Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

6 September 2017

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Innate responses to Toxoplasma gondii in mice and humans

6 September 2017

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Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors

6 September 2017

1 reference

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UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii

6 September 2017

1 reference

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Structure-Based Analysis of Toxoplasma gondii Profilin: A Parasite-Specific Motif Is Required for Recognition by Toll-Like Receptor 11

6 September 2017

1 reference

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Monocytes mediate mucosal immunity to Toxoplasma gondii

6 September 2017

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NF-kappaB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS.

6 September 2017

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A cell biological view of Toll-like receptor function: regulation through compartmentalization.

6 September 2017

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Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function.

6 September 2017

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Differential expression of IRF8 in subsets of macrophages and dendritic cells and effects of IRF8 deficiency on splenic B cell and macrophage compartments

6 September 2017

1 reference

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Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response.

6 September 2017

1 reference

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

6 September 2017

1 reference

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The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse

6 September 2017

1 reference

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The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

6 September 2017

1 reference

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The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

6 September 2017

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The evolution of vertebrate Toll-like receptors

6 September 2017

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TLR11 activation of dendritic cells by a protozoan profilin-like protein.

6 September 2017

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TLR9 is localized in the endoplasmic reticulum prior to stimulation

6 September 2017

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Neutrophils, dendritic cells and Toxoplasma.

6 September 2017

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

6 September 2017

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

6 September 2017

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ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells

6 September 2017

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Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

6 September 2017

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

6 September 2017

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Three novel mammalian toll-like receptors: gene structure, expression, and evolution

6 September 2017

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Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

6 September 2017

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In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

6 September 2017

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Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction

6 September 2017

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The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells

6 September 2017

1 reference

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Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

6 September 2017

1 reference

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Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha

6 September 2017

1 reference

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Interleukin-12 enhances murine survival against acute toxoplasmosis

6 September 2017

1 reference

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Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805684

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805684

Subcellular localization of Toll-like receptor 3 in human dendritic cells

14 September 2017

1 reference

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Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

14 September 2017

1 reference

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Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805684

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3805684

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

3 September 2018

1 reference

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ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro

3 September 2018

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Cutting Edge: Identification of c-Rel-Dependent and -Independent Pathways of IL-12 Production During Infectious and Inflammatory Stimuli

3 December 2018

1 reference

12 December 2020

The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense

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12 December 2020

Functional Inactivation of Immature Dendritic Cells by the Intracellular Parasite Toxoplasma gondii

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12 December 2020

Interleukin-12: a cytokine at the interface of inflammation and immunity

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12 December 2020

Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines

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12 December 2020

Identification of a Role for NF- B2 in the Regulation of Apoptosis and in Maintenance of T Cell-Mediated Immunity to Toxoplasma gondii

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1301301

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078692%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078692%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24078692%20AND%20SRC:MED&resulttype=core&format=json