Mechanisms of disease: the evolving role of regulatory T cells in atherosclerosis (Q37209541)

19 August 2017

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title

Mechanisms of disease: the evolving role of regulatory T cells in atherosclerosis (English)

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19 August 2017

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Jacob George

1

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19 August 2017

8 July 2008

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Nature Clinical Practice Cardiovascular Medicine

19 August 2017

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19 August 2017

5

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19 August 2017

9

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19 August 2017

531-540

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Inflammation, atherosclerosis, and coronary artery disease

19 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

The immune response in atherosclerosis: a double-edged sword

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Vaccination for atherosclerosis: a novel therapeutic paradigm

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Functional diversity of helper T lymphocytes

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Th17 cell differentiation: the long and winding road

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Natural versus adaptive regulatory T cells

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Tr1 cells: from discovery to their clinical application.

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Role of LAG-3 in regulatory T cells.

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

An essential role for Scurfin in CD4+CD25+ T regulatory cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

From vanilla to 28 flavors: multiple varieties of T regulatory cells

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Natural regulatory T cells: mechanisms of suppression

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Regulatory T cells in the periphery

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

TGF-beta: the missing link in CD4+CD25+ regulatory T cell-mediated immunosuppression

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Regulatory T cells in human autoimmune diseases

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Human regulatory T cells and their role in autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Regulatory T cells, tumour immunity and immunotherapy

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Innate and acquired immunity in atherogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

C-reactive protein comes of age.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Autoimmune and inflammatory mechanisms in atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Staining of endothelial cells and macrophages in atherosclerotic lesions with human heat-shock protein-reactive antisera

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Low density lipoprotein undergoes oxidative modification in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Immunolocalization of beta2-glycoprotein I (apolipoprotein H) to human atherosclerotic plaques: potential implications for lesion progression

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Induction of early atherosclerosis in LDL-receptor-deficient mice immunized with beta2-glycoprotein I

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Adoptive transfer of beta(2)-glycoprotein I-reactive lymphocytes enhances early atherosclerosis in LDL receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Cellular and humoral immune responses to heat shock protein 65 are both involved in promoting fatty-streak formation in LDL-receptor deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Induction of oral tolerance to oxidized low-density lipoprotein ameliorates atherosclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Inflammation and atherosclerosis: novel insights into plaque formation and destabilization

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

1 reference

7 January 2021

Suppression of early atherosclerosis in LDL-receptor deficient mice by oral tolerance with beta 2-glycoprotein I.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Hyperimmunization of apo-E-deficient mice with homologous malondialdehyde low-density lipoprotein suppresses early atherogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Induction of oral tolerance to HSP60 or an HSP60-peptide activates T cell regulation and reduces atherosclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Cytokines in atherosclerosis: pathogenic and regulatory pathways

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Protective Role of Interleukin-10 in Atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Disruption of TGF-β signaling in T cells accelerates atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Natural regulatory T cells control the development of atherosclerosis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Role of naturally occurring CD4+ CD25+ regulatory T cells in experimental atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Plaque rupture in humans and mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Perturbation of the T-Cell Repertoire in Patients With Unstable Angina

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Molecular Fingerprint of Interferon-γ Signaling in Unstable Angina

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

The serum concentration of active transforming growth factor-beta is severely depressed in advanced atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Serum levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Altered status of CD4(+)CD25(+) regulatory T cells in patients with acute coronary syndromes

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

The opposite-direction modulation of CD4+CD25+ Tregs and T helper 1 cells in acute coronary syndromes.

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions

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https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Statin therapy and autoimmune disease: from protein prenylation to immunomodulation

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Immunomodulation and vaccination for atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Recombinant antibodies to an oxidized low-density lipoprotein epitope induce rapid regression of atherosclerosis in apobec-1(-/-)/low-density lipoprotein receptor(-/-) mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPCARDIO1279

7 January 2021

Identifiers

DOI

10.1038/NCPCARDIO1279

1 reference

19 August 2017

1 reference

PubMed ID

18607396