Oxygen-derived free radicals and myocardial reperfusion injury: An overview (Q37188913)

18 August 2017

1 reference

title

Oxygen-derived free radicals and myocardial reperfusion injury: an overview (English)

1 reference

18 August 2017

Oxygen-derived free radicals and myocardial reperfusion injury: An overview (English)

1 reference

myocardial reperfusion injury

10 December 2022

1 reference

0 references

1 reference

Cardiology and cardiovascular medicine

inferred from title

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10 December 2022

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10 December 2022

author name string

R. Bolli

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1854667

10 December 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1854667

10 December 2022

publication date

1 March 1991

1 reference

full work available at URL

18 August 2017

http://link.springer.com/content/pdf/10.1007/BF00054747.pdf

file format

Portable Document Format

1 reference

http://link.springer.com/article/10.1007/BF00054747/fulltext.html

10 December 2022

1 reference

http://link.springer.com/content/pdf/10.1007/BF00054747

10 December 2022

1 reference

Cardiovascular Drugs and Therapy

10 December 2022

published in

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18 August 2017

5 Suppl 2

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18 August 2017

249-268

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Elevation in cytosolic free calcium concentration early in myocardial ischemia in perfused rat heart

18 August 2017

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Reperfusion injury and its pharmacologic modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

The stunned myocardium: prolonged, postischemic ventricular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Postischemic myocardial "stunning": a clinically relevant phenomenon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Oxygen toxicity, oxygen radicals, transition metals and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Oxypurinol limits myocardial stunning but does not reduce infarct size after reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

F(ab')2 fragments of anti-Mo1 (904) monoclonal antibodies do not prevent myocardial stunning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Granulocytes cause reperfusion ventricular dysfunction after 15-minute ischemia in the dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Alleviation of myocardial stunning by leukocyte and platelet depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Alterations in cardiac sarcoplasmic reticulum calcium transport in the postischemic "stunned" myocardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Evidence for a reversible oxygen radical-mediated component of reperfusion injury: reduction by recombinant human superoxide dismutase administered at the time of reflow

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Superoxide dismutase reduces reperfusion arrhythmias but fails to salvage regional function or myocardium at risk in conscious dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

"Reperfusion injury" by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary microvasculature, and regional myocardial blood flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Glutathione redox pathway and reperfusion injury. Effect of N-acetylcysteine on infarct size and ventricular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Effects of propranolol and diltiazem alone and in combination on the recovery of left ventricular segmental function after temporary coronary occlusion and long-term reperfusion in conscious dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Reversibly injured, postischemic canine myocardium retains normal contractile reserve

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Excitation-contraction coupling in postischemic myocardium. Does failure of activator Ca2+ transients underlie stunning?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Oxygen-derived free radicals in postischemic tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Can superoxide dismutase alter myocardial infarct size?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

The independent effects of oxygen radical scavengers on canine infarct size. Reduction by superoxide dismutase but not catalase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Reduction in experimental infarct size by recombinant human superoxide dismutase: insights into the pathophysiology of reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Failure of superoxide dismutase and catalase to alter size of infarction in conscious dogs after 3 hours of occlusion followed by reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Failure of superoxide dismutase to limit size of myocardial infarction after 40 minutes of ischemia and 4 days of reperfusion in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Effect of superoxide dismutase on myocardial infarct size in the canine heart after 6 hours of regional ischemia and reperfusion: a demonstration of myocardial salvage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Reduction of the size of infarction by allopurinol in the ischemic-reperfused canine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Failure of the xanthine oxidase inhibitor allopurinol to limit infarct size after ischemia and reperfusion in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Therapy to reduce free radicals during early reperfusion does not limit the size of myocardial infarcts caused by 90 minutes of ischemia in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Limitation of myocardial infarct size by superoxide dismutase as an adjunct to reperfusion after different durations of coronary occlusion in the pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00054747

Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart

21 January 2018

1 reference

12 December 2020

The iron chelator desferrioxamine attenuates postischemic ventricular dysfunction.

1 reference

12 December 2020

Possible role for cytotoxic oxygen metabolites in the pathogenesis of cardiac ischemic injury

1 reference

12 December 2020

Use of spin traps in intact animals undergoing myocardial ischemia/reperfusion: a new approach to assessing the role of oxygen radicals in myocardial "stunning".

1 reference

12 December 2020

Singlet oxygen-induced arrhythmias. Dose- and light-response studies for photoactivation of rose bengal in the rat heart

1 reference

12 December 2020

Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase and catalase.

1 reference

12 December 2020

Xanthine oxidase as a source of free radical damage in myocardial ischemia

1 reference

12 December 2020

Prolonged abnormalities of left ventricular diastolic wall thinning in the "stunned" myocardium in conscious dogs: time course and relation to systolic function

1 reference

12 December 2020

Conjugated dienes in ischemic and reperfused myocardium: an in vivo chemical signature of oxygen free radical mediated injury

1 reference

12 December 2020

Contractile dysfunction and ATP depletion after transient calcium overload in perfused ferret hearts

1 reference

12 December 2020

Free radicals and myocardial ischemia and reperfusion injury

1 reference

12 December 2020

In vivo infusion of oxygen free radical substrates causes myocardial systolic, but not diastolic dysfunction.

1 reference

12 December 2020

Free radical-producing enzyme, xanthine oxidase, is undetectable in human hearts

1 reference

12 December 2020

The oxygen paradox and the calcium paradox: two facets of the same problem?

1 reference

12 December 2020

Superoxide dismutase plus catalase enhances the efficacy of hypothermic cardioplegia to protect the globally ischemic, reperfused heart

1 reference

12 December 2020

Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy

1 reference

12 December 2020

Coronary arterial reperfusion. III. Early and late effects on regional myocardial function and dimensions in conscious dogs

1 reference

12 December 2020

Intracellular free calcium concentration measured with 19F NMR spectroscopy in intact ferret hearts

1 reference

12 December 2020

Evidence for a role of iron-catalyzed oxidants in functional and metabolic stunning in the canine heart

1 reference

12 December 2020

Reperfusion-induced arrhythmias: A study of the role of xanthine oxidase-derived free radicals in the rat heart

1 reference

12 December 2020

Influence of neutrophil depletion on myocardial function and flow after reversible ischemia

1 reference

12 December 2020

Role of intracellular Na+ in Ca2+ overload and depressed recovery of ventricular function of reperfused ischemic rat hearts. Possible involvement of H+-Na+ and Na+-Ca2+ exchange

1 reference

12 December 2020

Myocardial consequences of reperfusion

1 reference

12 December 2020

The oxygen free radical system: a fundamental mechanism in the production of myocardial necrosis

1 reference

12 December 2020

Validation of a single crystal for measurement of transmural and epicardial thickening.

1 reference

12 December 2020

Depression of heart sarcolemmal Ca2+-pump activity by oxygen free radicals

1 reference

12 December 2020

Neutrophil depletion does not prevent myocardial dysfunction after brief coronary occlusion

1 reference

12 December 2020

A comparative study of free radical scavengers in cardioplegic solutions. Improved protection with peroxidase

1 reference

12 December 2020

Influence of exogenously generated oxidant species on myocardial function

1 reference

12 December 2020

Redox modification of sodium-calcium exchange activity in cardiac sarcolemmal vesicles

1 reference

12 December 2020

Regional myocardial functional and electrophysiological alterations after brief coronary artery occlusion in conscious dogs

1 reference

12 December 2020

Early treatment with deferoxamine limits myocardial ischemic/reperfusion injury

1 reference

12 December 2020

Effect of diltiazem and propranolol on left ventricular segmental relaxation during temporary coronary arterial occlusion and one month reperfusion in conscious dogs

1 reference

12 December 2020

Measurement of superoxide-derived free radicals in the reperfused heart. Evidence for a free radical mechanism of reperfusion injury

1 reference

12 December 2020

Myocardial neutrophil accumulation during reperfusion after reversible or irreversible ischemic injury

1 reference

12 December 2020

Canine myocardial reperfusion injury: protection by a free radical scavenger, N-2-mercaptopropionyl glycine

1 reference

12 December 2020

The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH.

1 reference

12 December 2020

Factors involved in salvaging ischemic myocardium: effect of reperfusion of arterial blood

1 reference

12 December 2020

Recruitment of inotropic reserve in "stunned" myocardium by the cardiotonic agent AR-L 57

1 reference

12 December 2020

Free radical scavengers improve functional recovery of stunned myocardium in a model of surgical coronary revascularization

1 reference

12 December 2020

Effect of human recombinant superoxide dismutase on canine myocardial infarction

1 reference

12 December 2020

Urate production by human heart

1 reference

12 December 2020

Time course and determinants of recovery of function after reversible ischemia in conscious dogs.

1 reference

12 December 2020

Significance of xanthine oxidase in capillary endothelial cells

1 reference

12 December 2020

Reperfusion-induced arrhythmias: mechanisms and prevention

1 reference

12 December 2020

Cytosolic calcium transients from the beating mammalian heart

1 reference

12 December 2020

Superoxide dismutase and catalase reduce infarct size in a porcine myocardial occlusion-reperfusion model.

1 reference

12 December 2020

Direct measurement of free radical generation following reperfusion of ischemic myocardium

1 reference

12 December 2020

Protein damage and degradation by oxygen radicals. I. general aspects

1 reference

12 December 2020

Myocardial alterations due to free-radical generation

1 reference

12 December 2020

Limitation of infarct size for 24 hours by combined treatment with allopurinol plus verapamil during acute myocardial infarction in the dog.

1 reference

12 December 2020

Effect of some free radical scavengers on reperfusion induced arrhythmias in the isolated rat heart

1 reference

12 December 2020

Pathophysiology and pathogenesis of stunned myocardium. Depressed Ca2+ activation of contraction as a consequence of reperfusion-induced cellular calcium overload in ferret hearts

1 reference

12 December 2020

Beneficial effects of oxypurinol pretreatment in stunned, reperfused canine myocardium

1 reference

12 December 2020

Effect of intracoronary superoxide dismutase on regional function in stunned myocardium.

1 reference

12 December 2020

Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol

1 reference

12 December 2020

Time course of functional and biochemical recovery of myocardium salvaged by reperfusion

1 reference

12 December 2020

Does captopril attenuate reperfusion-induced myocardial dysfunction by scavenging free radicals?

1 reference

12 December 2020

Acidosis during early reperfusion prevents myocardial stunning in perfused ferret hearts

1 reference

12 December 2020

Nonuniform transmural recovery of contractile function in stunned myocardium

1 reference

12 December 2020

Myocardial free-radical injury after cardioplegia.

1 reference

12 December 2020

Free radicals and calcium: Simultaneous interacting triggers as determinants of vulnerability to reperfusion-induced arrhythmias in the rat heart

1 reference

12 December 2020

O2 free radicals: cause of ischemia-reperfusion injury to cardiac Na+-K+-ATPase

1 reference

12 December 2020

Absence of detectable xanthine oxidase in human myocardium

1 reference

12 December 2020

Salvage of myocardial function by coronary artery reperfusion 1, 2, and 3 hours after occlusion in conscious dogs

1 reference

12 December 2020

Superoxide dismutase and the reduction of reperfusion-induced arrhythmias: in vivo dose-response studies in the rat.

1 reference

12 December 2020

Quantitative identification of superoxide anion as a negative inotropic species

1 reference

12 December 2020

Lipoxygenase inhibitor nafazatrom fails to attenuate postischaemic ventricular dysfunction.

1 reference

12 December 2020

Effects of supplementing hypothermic crystalloid cardioplegic solution with catalase, superoxide dismutase, allopurinol, or deferoxamine on functional recovery of globally ischemic and reperfused isolated hearts.

1 reference

12 December 2020

Mechanisms of reoxygenation-induced calcium overload in cultured chick embryo heart cells

1 reference

12 December 2020

Effect of verapamil on postischemic "stunned" myocardium: importance of the timing of treatment

1 reference

12 December 2020

Oxygen radicals in cardiac surgery

1 reference

12 December 2020

Reversal of dysfunction in postischemic stunned myocardium by epinephrine and postextrasystolic potentiation

1 reference

12 December 2020

Sustained regional dysfunction produced by prolonged coronary stenosis: gradual recovery after reperfusion

1 reference

12 December 2020

Persistence of myocardial injury following brief periods of coronary occlusion.

1 reference

12 December 2020

Studies of experimental coronary artery reperfusion. Effects on infarct size, myocardial function, biochemistry, ultrastructure and microvascular damage.

1 reference

12 December 2020

Protection afforded by allopurinol in the first 24 hours of coronary occlusion is diminished after 48 hours

1 reference

12 December 2020

Recovery of left ventricular segmental function after long-term reperfusion following temporary coronary occlusion in conscious dogs. Comparison of 2- and 4-hour occlusions

1 reference

12 December 2020

The activity of xanthine oxidase in heart of pigs, guinea pigs, rabbits, rats, and humans.

1 reference

12 December 2020

Myocardial dysfunction and ultrastructural alterations mediated by oxygen metabolites.

1 reference

12 December 2020

Effects of hydrogen peroxide on cardiac function and post-ischaemic functional recovery in the isolated 'working' rat heart

1 reference

12 December 2020

Amelioration of postischemic stunning by deferoxamine-blood cardioplegia.

1 reference

12 December 2020

Effect of oxygen-derived free radical scavengers on infarct size following six hours of permanent coronary artery occlusion: salvage or delay of myocyte necrosis?

1 reference

12 December 2020

Myocardial ischemia and reperfusion: direct evidence for free radical generation by electron spin resonance spectroscopy

1 reference

12 December 2020

Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury

1 reference

12 December 2020

Prevention of granulocyte-mediated oxidant lung injury in rats by a hydroxyl radical scavenger, dimethylthiourea

1 reference

12 December 2020

Depression of regional blood flow and wall thickening after brief coronary occlusions

1 reference

12 December 2020

Attenuation of dysfunction in the postischemic 'stunned' myocardium by dimethylthiourea

1 reference

12 December 2020

Reperfusion-induced arrhythmias and oxygen-derived free radicals. Studies with "anti-free radical" interventions and a free radical-generating system in the isolated perfused rat heart

1 reference

12 December 2020

Effect of superoxide dismutase and catalase, given separately, on myocardial "stunning".

1 reference

12 December 2020

Hydrogen peroxide and hydroxyl radical mediation of activated leukocyte depression of cardiac sarcoplasmic reticulum. Participation of the cyclooxygenase pathway

1 reference

12 December 2020

Differential sensitivity of canine cardiac sarcolemmal and microsomal enzymes to inhibition by free radical-induced lipid peroxidation

1 reference

12 December 2020

Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone

1 reference

12 December 2020

The xanthine oxidase inhibitor oxypurinol does not limit infarct size in a canine model of 40 minutes of ischemia with reperfusion

1 reference

12 December 2020

Improved recovery of myocardial segment function following a short coronary occlusion in dogs by nicorandil, a potential new antianginal agent, and nifedipine

1 reference

12 December 2020

Differential enhancement of postischemic segmental systolic thickening by diltiazem

1 reference

12 December 2020

Sustained limitation by superoxide dismutase of canine myocardial injury due to regional ischemia followed by reperfusion

1 reference

12 December 2020

Inhibition of surgically induced ischemia/reperfusion injury by oxygen free radical scavengers.

1 reference

12 December 2020

Intracoronary superoxide dismutase for the treatment of "reperfusion injury", A blind randomized placebo-controlled trial in ischemic, reperfused porcine hearts

1 reference

12 December 2020

Evidence for a pathogenetic role of xanthine oxidase in the "stunned" myocardium

1 reference

12 December 2020

Beneficial actions of superoxide dismutase and catalase in stunned myocardium of dogs

1 reference

12 December 2020

N-2-mercaptopropionylglycine improves recovery of myocardial function after reversible regional ischemia.

1 reference

12 December 2020

Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro

1 reference

12 December 2020

Nifedipine administered after reperfusion ablates systolic contractile dysfunction of postischemic "stunned" myocardium

1 reference

12 December 2020

Superoxide dismutase plus catalase improve contractile function in the canine model of the "stunned myocardium"

1 reference

12 December 2020

Protection by superoxide dismutase and catalase in the isolated rat heart reperfused after prolonged cardioplegia: a combined study of metabolic, functional, and morphometric ultrastructural variables

1 reference

12 December 2020

Influence of oxygen radicals generated by xanthine oxidase in the isolated perfused rat heart

1 reference

12 December 2020

Calcium and its role in myocardial cell injury during ischemia and reperfusion

1 reference

12 December 2020

O2 free radical-mediated myocardial and vascular dysfunction

1 reference

12 December 2020

Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

1 reference

12 December 2020

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GR Heyndrickx

1978

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R Bolli

1988

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R Bolli

1989

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1986

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1987

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1984

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10 December 2022

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10 December 2022

Identifiers

DOI

10.1007/BF00054747

1 reference

18 August 2017

1 reference