Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria. (Q37147220)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19012394%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Surprising alteration of antibacterial activity of 5"-modified neomycin against resistant bacteria (English)

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17 January 2020

6

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17 January 2020

author name string

Jianjun Zhang

1

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17 January 2020

Fang-I Chiang

2

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17 January 2020

Long Wu

3

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17 January 2020

Przemyslaw Greg Czyryca

4

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17 January 2020

Ding Li

5

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17 January 2020

language of work or name

English

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publication date

1 December 2008

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Journal of Medicinal Chemistry

17 January 2020

published in

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17 January 2020

volume

51

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17 January 2020

issue

23

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17 January 2020

page(s)

7563-7573

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Investigation of the regioselectivity for the staudinger reaction and its application for the synthesis of aminoglycosides with N-1 modification.

17 January 2020

cites work

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Sonication-assisted library synthesis of oxazolidinone-carbohydrate conjugates.

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Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

6 September 2017

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RNA−Ligand Interactions: Affinity and Specificity of Aminoglycoside Dimers and Acridine Conjugates to the HIV-1 Rev Response Element

6 September 2017

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Versatility of aminoglycosides and prospects for their future

6 September 2017

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The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography

6 September 2017

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Monitoring antimicrobial use and resistance: comparison with a national benchmark on reducing vancomycin use and vancomycin-resistant enterococci

6 September 2017

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Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry

6 September 2017

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Aminoglycoside-streptothricin resistance gene cluster aadE-sat4-aphA-3 disseminated among multiresistant isolates of Enterococcus faecium

6 September 2017

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Identification of aminoglycoside-modifying enzymes by susceptibility testing: epidemiology of methicillin-resistant Staphylococcus aureus in Japan

6 September 2017

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Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance

6 September 2017

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Characterization of the extended-spectrum beta-lactamase reference strain, Klebsiella pneumoniae K6 (ATCC 700603), which produces the novel enzyme SHV-18

6 September 2017

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Python: a programming language for software integration and development

6 September 2017

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Aminoglycoside-modifying enzymes

6 September 2017

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Aminoglycosides: activity and resistance

6 September 2017

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Sequence and characterization of a novel chromosomal aminoglycoside phosphotransferase gene, aph (3')-IIb, in Pseudomonas aeruginosa

6 September 2017

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Molecular characterization and multilaboratory evaluation of Enterococcus faecalis ATCC 51299 for quality control of screening tests for vancomycin and high-level aminoglycoside resistance in enterococci

6 September 2017

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Broad spectrum aminoglycoside phosphotransferase type III from Enterococcus: overexpression, purification, and substrate specificity

6 September 2017

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Kinetic mechanism of aminoglycoside phosphotransferase type IIIa. Evidence for a Theorell-Chance mechanism

6 September 2017

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Conformational constraint as a means for understanding RNA-aminoglycoside specificity.

6 September 2017

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Glycodiversification for the optimization of the kanamycin class aminoglycosides

14 September 2017

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Branched aminoglycosides: biochemical studies and antibacterial activity of neomycin B derivatives

3 September 2018

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Tuning the regioselectivity of the Staudinger reaction for the facile synthesis of kanamycin and neomycin class antibiotics with N-1 modification.

3 September 2018

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A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.

3 September 2018

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RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides.

3 September 2018

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Detection of genes encoding aminoglycoside-modifying enzymes in staphylococci by polymerase chain reaction and dot blot hybridization

3 September 2018

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3 September 2018

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Multisite Modification of Neomycin B: Combined Mitsunobu and Click Chemistry Approach

3 September 2018

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12 December 2020

Design and synthesis of a structurally constrained aminoglycoside

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12 December 2020

The prevalence of aminoglycoside resistance and corresponding resistance genes in clinical isolates of staphylococci from 19 European hospitals

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12 December 2020

A new class of branched aminoglycosides: pseudo-pentasaccharide derivatives of neomycin B

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12 December 2020

Identifiers

DOI

10.1021/JM800997S

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19012394%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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17 January 2020

PubMed publication ID

19012394

1 reference