General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal (Q37143127)

18 August 2017

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title

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal (English)

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18 August 2017

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Nicholas P Franks

1

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language of work or name

English

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publication date

1 May 2008

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Nature Reviews Neuroscience

18 August 2017

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18 August 2017

9

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18 August 2017

370-386

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18 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/nrn2372

18 August 2017

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cites work

Molecular and cellular mechanisms of general anaesthesia

1 reference

Mechanisms of actions of inhaled anesthetics

31 March 2020

1 reference

Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration

31 March 2020

1 reference

Molecular and neuronal substrates for general anaesthetics

31 March 2020

1 reference

Different Actions of Anticonvulsant and Anesthetic Barbiturates Revealed by Use of Cultured Mammalian Neurons

31 March 2020

1 reference

Pentobarbital: Differential Postsynaptic Actions on Sympathetic Ganglion Cells

31 March 2020

1 reference

Barbiturate receptor sites are coupled to benzodiazepine receptors

31 March 2020

1 reference

Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

31 March 2020

1 reference

Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon.

31 March 2020

1 reference

Nonhalogenated alkane anesthetics fail to potentiate agonist actions on two ligand-gated ion channels

31 March 2020

1 reference

Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor

31 March 2020

1 reference

Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons.

31 March 2020

1 reference

Major role for tonic GABAA conductances in anesthetic suppression of intrinsic neuronal excitability

31 March 2020

1 reference

Selective enhancement of tonic GABAergic inhibition in murine hippocampal neurons by low concentrations of the volatile anesthetic isoflurane.

31 March 2020

1 reference

Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics.

31 March 2020

1 reference

The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

31 March 2020

1 reference

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

31 March 2020

1 reference

General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

31 March 2020

1 reference

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

31 March 2020

1 reference

Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane

31 March 2020

1 reference

The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations

31 March 2020

1 reference

Volatile anesthetic actions on the GABAA receptors: contrasting effects of alpha 1(S270) and beta 2(N265) point mutations

31 March 2020

1 reference

Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

31 March 2020

1 reference

Defining the propofol binding site location on the GABAA receptor

31 March 2020

1 reference

Halogenated diazirines as photolabel mimics of the inhaled haloalkane anesthetics

31 March 2020

1 reference

Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain.

31 March 2020

1 reference

2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: a derivative of the stereoselective general anesthetic etomidate for photolabeling ligand-gated ion channels

31 March 2020

1 reference

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

31 March 2020

1 reference

Propofol and other intravenous anesthetics have sites of action on the gamma-aminobutyric acid type A receptor distinct from that for isoflurane.

31 March 2020

1 reference

Agonist gating and isoflurane potentiation in the human gamma-aminobutyric acid type A receptor determined by the volume of a second transmembrane domain residue.

31 March 2020

1 reference

Evidence for a common binding cavity for three general anesthetics within the GABAA receptor.

31 March 2020

1 reference

Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1 subunit: implications for modulation by inhaled anesthetics and ion channel structure

31 March 2020

1 reference

Transmembrane residues define the action of isoflurane at the GABAA receptor alpha-3 subunit.

31 March 2020

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Methionine 286 in transmembrane domain 3 of the GABAA receptor beta subunit controls a binding cavity for propofol and other alkylphenol general anesthetics

31 March 2020

1 reference

Molecular determinants for the action of general anesthetics at recombinant alpha(2)beta(3)gamma(2)gamma-aminobutyric acid(A) receptors.

31 March 2020

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A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation

31 March 2020

1 reference

Identification of a molecular target mediating the general anesthetic actions of pentobarbital.

31 March 2020

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Distinct molecular targets for the central respiratory and cardiac actions of the general anesthetics etomidate and propofol

31 March 2020

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Gamma-aminobutyric acid type A receptor beta 2 subunit mediates the hypothermic effect of etomidate in mice

31 March 2020

1 reference

GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol

31 March 2020

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Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate.

31 March 2020

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Stereoselective and non-stereoselective actions of isoflurane on the GABAA receptor

31 March 2020

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Stereoselective effects of etomidate optical isomers on gamma-aminobutyric acid type A receptors and animals

31 March 2020

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Preparation of barbiturate optical isomers and their effects on GABA(A) receptors.

31 March 2020

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Stereoselective loss of righting reflex in rats by isoflurane.

31 March 2020

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General anesthetics hyperpolarize neurons in the vertebrate central nervous system.

31 March 2020

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Volatile general anaesthetics activate a novel neuronal K+ current

31 March 2020

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Potassium leak channels and the KCNK family of two-P-domain subunits

31 March 2020

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Properties and modulation of mammalian 2P domain K+ channels.

31 March 2020

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Inhalational anesthetics activate two-pore-domain background K+ channels

31 March 2020

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Potent activation of the human tandem pore domain K channel TRESK with clinical concentrations of volatile anesthetics

31 March 2020

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Motoneurons express heteromeric TWIK-related acid-sensitive K+ (TASK) channels containing TASK-1 (KCNK3) and TASK-3 (KCNK9) subunits

31 March 2020

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Determinants of the anesthetic sensitivity of two-pore domain acid-sensitive potassium channels: molecular cloning of an anesthetic-activated potassium channel from Lymnaea stagnalis

31 March 2020

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Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane

31 March 2020

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Mechanism of anesthesia revealed by shunting actions of isoflurane on thalamocortical neurons.

31 March 2020

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The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics.

31 March 2020

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Serotonergic raphe neurons express TASK channel transcripts and a TASK-like pH- and halothane-sensitive K+ conductance.

31 March 2020

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Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.

31 March 2020

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Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action

31 March 2020

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An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.

31 March 2020

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Stereospecific effects of inhalational general anesthetic optical isomers on nerve ion channels

31 March 2020

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TREK-1, a K+ channel involved in neuroprotection and general anesthesia

31 March 2020

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The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.

31 March 2020

1 reference

NMDA receptor subunits: diversity, development and disease

31 March 2020

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Effects of halothane on glutamate receptor-mediated excitatory postsynaptic currents. A patch-clamp study in adult mouse hippocampal slices.

31 March 2020

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Determinants of the sensitivity of AMPA receptors to xenon

31 March 2020

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The role of the NMDA synapse in general anesthesia

31 March 2020

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Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels. Comparison with isoflurane and ethanol

31 March 2020

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Modulation of NMDA receptor function by ketamine and magnesium. Part II: interactions with volatile anesthetics

31 March 2020

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Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes.

31 March 2020

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Differential modulation of human N-methyl-D-aspartate receptors by structurally diverse general anesthetics.

31 March 2020

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How does xenon produce anaesthesia?

31 March 2020

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Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin

31 March 2020

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Xenon suppresses nociceptive reflex in newborn rat spinal cord in vitro; comparison with nitrous oxide.

31 March 2020

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Effects of xenon on in vitro and in vivo models of neuronal injury

31 March 2020

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Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor by the anesthetics xenon and isoflurane: evidence from molecular modeling and electrophysiology

31 March 2020

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Antagonists of the NMDA receptor-channel complex and motor coordination.

31 March 2020

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Reevaluation of ACEA 1021 as an antagonist at the strychnine-insensitive glycine site of the N-methyl-D-aspartate receptor.

31 March 2020

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S-ketamine anesthesia increases cerebral blood flow in excess of the metabolic needs in humans

31 March 2020

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Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes

31 March 2020

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Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics

31 March 2020

1 reference

Convergent and reciprocal modulation of a leak K+ current and I(h) by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones

31 March 2020

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HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents.

31 March 2020

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Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons

31 March 2020

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The sensitivity of hyperpolarization-activated cation current (Ih) to propofol in rat area postrema neurons

31 March 2020

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Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals

31 March 2020

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Effects of alcohols and anesthetics on recombinant voltage-gated Na+ channels

31 March 2020

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Isoform-selective effects of isoflurane on voltage-gated Na+ channels.

31 March 2020

1 reference

Propofol anesthesia and cerebral blood flow changes elicited by vibrotactile stimulation: a positron emission tomography study

31 March 2020

1 reference

Effects of sevoflurane, propofol, and adjunct nitrous oxide on regional cerebral blood flow, oxygen consumption, and blood volume in humans

31 March 2020

1 reference

Effects of xenon anesthesia on cerebral blood flow in humans: a positron emission tomography study.

31 March 2020

1 reference

Toward a unified theory of narcosis: brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness.

31 March 2020

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Impaired thalamocortical connectivity in humans during general-anesthetic-induced unconsciousness

31 March 2020

1 reference

Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study.

31 March 2020

1 reference

Activity of midbrain reticular formation and neocortex during the progression of human non-rapid eye movement sleep.

31 March 2020

1 reference

Functional neuroimaging of normal human sleep by positron emission tomography

31 March 2020

1 reference

Brain function in coma, vegetative state, and related disorders

31 March 2020

1 reference

The precuneus: a review of its functional anatomy and behavioural correlates

31 March 2020

1 reference

Thalamocortical oscillations in the sleeping and aroused brain

31 March 2020

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Sleep and arousal: thalamocortical mechanisms

31 March 2020

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Thalamic synchrony and dynamic regulation of global forebrain oscillations.

31 March 2020

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The G. L. Brown lecture. Adventures in anaesthesia.

31 March 2020

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Synaptic and membrane mechanisms underlying synchronized oscillations in the ferret lateral geniculate nucleus in vitro

31 March 2020

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Feedback inhibition controls spike transfer in hybrid thalamic circuits

31 March 2020

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Regional cerebral blood flow changes as a function of delta and spindle activity during slow wave sleep in humans.

31 March 2020

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Pontine cholinergic mechanisms modulate the cortical electroencephalographic spindles of halothane anesthesia.

31 March 2020

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Anesthetic effects on electrophysiologic recordings

31 March 2020

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Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anaesthetized with propofol or sevoflurane

31 March 2020

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Monitoring consciousness: the current status of EEG-based depth of anaesthesia monitors.

31 March 2020

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Isoflurane induces dose-dependent changes of thalamic somatosensory information transfer.

31 March 2020

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What can in vivo electrophysiology in animal models tell us about mechanisms of anaesthesia?

31 March 2020

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Halothane-induced hyperpolarization and depression of postsynaptic potentials of guinea pig thalamic neurons in vitro

31 March 2020

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Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons.

31 March 2020

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An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons

31 March 2020

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Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels

31 March 2020

1 reference

Looking back: corticothalamic feedback and early visual processing

31 March 2020

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Synaptic mechanisms of thiopental-induced alterations in synchronized cortical activity

31 March 2020

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Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABAA receptor-mediated inhibition

31 March 2020

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Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia.

31 March 2020

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Activation of ventrolateral preoptic neurons during sleep

31 March 2020

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Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat.

31 March 2020

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Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats.

31 March 2020

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Brain structures and mechanisms involved in the generation of NREM sleep: focus on the preoptic hypothalamus.

31 March 2020

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Sleep-waking discharge patterns of median preoptic nucleus neurons in rats.

31 March 2020

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Gabaergic neurons with alpha2-adrenergic receptors in basal forebrain and preoptic area express c-Fos during sleep

31 March 2020

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31 March 2020

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Sleep-waking discharge of basal forebrain projection neurons in cats

31 March 2020

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Cerebral hypnogenic centers

31 March 2020

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The sleep switch: hypothalamic control of sleep and wakefulness

31 March 2020

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Afferents to the ventrolateral preoptic nucleus.

31 March 2020

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A putative flip-flop switch for control of REM sleep

31 March 2020

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Sleep deprivation potentiates the onset and duration of loss of righting reflex induced by propofol and isoflurane

31 March 2020

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Prolonged sedation with propofol in the rat does not result in sleep deprivation

31 March 2020

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Sleep, anesthesiology, and the neurobiology of arousal state control.

31 March 2020

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Projections of cholinergic and non-cholinergic neurons of the brainstem core to relay and associational thalamic nuclei in the cat and macaque monkey.

31 March 2020

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Neuronal activity in the peribrachial area: relationship to behavioral state control.

31 March 2020

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From waking to sleeping: neuronal and chemical substrates

31 March 2020

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Thalamic microinjection of nicotine reverses sevoflurane-induced loss of righting reflex in the rat.

31 March 2020

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Physostigmine reverses propofol-induced unconsciousness and attenuation of the auditory steady state response and bispectral index in human volunteers.

31 March 2020

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Interaction of intravenous anesthetics with recombinant human M1-M3 muscarinic receptors expressed in chinese hamster ovary cells.

31 March 2020

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Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected.

31 March 2020

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Differential sensitivities of mammalian neuronal and muscle nicotinic acetylcholine receptors to general anesthetics.

31 March 2020

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Heteromeric nicotinic inhibition by isoflurane does not mediate MAC or loss of righting reflex

31 March 2020

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Reversible analgesia, atonia, and loss of consciousness on bilateral intracerebral microinjection of pentobarbital

31 March 2020

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Neural pathways associated with loss of consciousness caused by intracerebral microinjection of GABA A-active anesthetics

31 March 2020

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Neuroanatomical correlates of brainstem coma

31 March 2020

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Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle.

31 March 2020

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Effects of locus coeruleus activation on electroencephalographic activity in neocortex and hippocampus.

31 March 2020

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The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes

31 March 2020

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The septohippocampal system participates in general anesthesia.

31 March 2020

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The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects

31 March 2020

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31 March 2020

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Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: a study of D- and L-derivatives in canine narcolepsy.

31 March 2020

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Wake-promoting actions of dopamine D1 and D2 receptor stimulation

31 March 2020

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Anesthetic influences on the basal activity and pharmacological responsiveness of nigrostriatal dopamine neurons

31 March 2020

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Identification of wake-active dopaminergic neurons in the ventral periaqueductal gray matter.

31 March 2020

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Acetylcholine liberation from cerebral cortex during paradoxical (REM) sleep.

31 March 2020

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Cellular bases of neocortical activation: modulation of neural oscillations by the nucleus basalis and endogenous acetylcholine

31 March 2020

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Modification of neocortical acetylcholine release and electroencephalogram desynchronization due to brainstem stimulation by drugs applied to the basal forebrain.

31 March 2020

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Sleep induction by microinjection of pentobarbital into the medial preoptic area in rats

31 March 2020

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The hypnotic effect of propofol in the medial preoptic area of the rat.

31 March 2020

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The role of histamine and the tuberomamillary nucleus in the nervous system

31 March 2020

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Histamine-containing neurons in the rat hypothalamus

31 March 2020

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Extracellular histamine levels in the feline preoptic/anterior hypothalamic area during natural sleep-wakefulness and prolonged wakefulness: an in vivo microdialysis study

31 March 2020

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31 March 2020

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Neuronal activity of histaminergic tuberomammillary neurons during wake-sleep states in the mouse.

31 March 2020

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The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway

31 March 2020

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Interactions between neuronal histamine and halothane anesthesia in rats.

31 March 2020

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Orexinergic neurons and barbiturate anesthesia.

31 March 2020

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An essential role for orexins in emergence from general anesthesia

31 March 2020

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The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

31 March 2020

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Fos expression in orexin neurons varies with behavioral state.

31 March 2020

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Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

31 March 2020

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Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

31 March 2020

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Arousal effect of orexin A depends on activation of the histaminergic system

31 March 2020

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Role of hydrogen bonding in general anesthesia.

31 March 2020

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A Unitary Theory of Anesthesia Based on Lateral Phase Separations in Nerve Membranes

31 March 2020

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Molecular mechanisms of general anaesthesia

31 March 2020

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Partitioning of long-chain alcohols into lipid bilayers: implications for mechanisms of general anesthesia

31 March 2020

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Do general anaesthetics act by competitive binding to specific receptors?

31 March 2020

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Mapping of general anaesthetic target sites provides a molecular basis for cutoff effects

31 March 2020

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Effects of general anesthetics on the bacterial luciferase enzyme from Vibrio harveyi: an anesthetic target site with differential sensitivity.

31 March 2020

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Thermodynamics of anesthetic/protein interactions. Temperature studies on firefly luciferase

31 March 2020

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Temperature dependence of the potency of volatile general anesthetics: implications for in vitro experiments.

31 March 2020

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Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures

31 March 2020

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Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein

31 March 2020

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Protein crystallography under xenon and nitrous oxide pressure: comparison with in vivo pharmacology studies and implications for the mechanism of inhaled anesthetic action.

31 March 2020

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The common chemical motifs within anesthetic binding sites

31 March 2020

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The general anesthetic propofol slows deactivation and desensitization of GABA(A) receptors.

31 March 2020

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Effects of halothane on GABA(A) receptor kinetics: evidence for slowed agonist unbinding.

31 March 2020

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Gating allosterism at a single class of etomidate sites on alpha1beta2gamma2L GABA A receptors accounts for both direct activation and agonist modulation

31 March 2020

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Cholinergic projections from the midbrain and pons to the thalamus in the rat, identified by combined retrograde tracing and choline acetyltransferase immunohistochemistry.

31 March 2020

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Projections of brainstem core cholinergic and non-cholinergic neurons of cat to intralaminar and reticular thalamic nuclei

31 March 2020

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Cholinergic neurons of the laterodorsal tegmental nucleus: efferent and afferent connections.

31 March 2020

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Identification of sleep-promoting neurons in vitro.

31 March 2020

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The adrenergic innervation of the rat thalamus as revealed by the glyoxylic acid fluorescence method.

31 March 2020

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The efferent projections from the reticular formation and the locus coeruleus studied by anterograde and retrograde axonal transport in the rat.

31 March 2020

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Brainstem projections to midline and intralaminar thalamic nuclei of the rat.

31 March 2020

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A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat

31 March 2020

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Neurons containing hypocretin (orexin) project to multiple neuronal systems

31 March 2020

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Selective action of orexin (hypocretin) on nonspecific thalamocortical projection neurons.

31 March 2020

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Organization of histaminergic fibers in the rat brain

31 March 2020

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Histamine-immunoreactive nerve fibers in the rat brain

31 March 2020

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Subregional organization of preoptic area/anterior hypothalamic projections to arousal-related monoaminergic cell groups

31 March 2020

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Preoptic area warming inhibits wake-active neurons in the perifornical lateral hypothalamus.

31 March 2020

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Efferent projections from the median preoptic nucleus to sleep- and arousal-regulatory nuclei in the rat brain

31 March 2020

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Innervation of orexin/hypocretin neurons by GABAergic, glutamatergic or cholinergic basal forebrain terminals evidenced by immunostaining for presynaptic vesicular transporter and postsynaptic scaffolding proteins

31 March 2020

1 reference

Brainstem afferents to the magnocellular basal forebrain studied by axonal transport, immunohistochemistry, and electrophysiology in the rat.

31 March 2020

1 reference

Influence of age on hypnotic requirement, bispectral index, and 95% spectral edge frequency associated with sedation induced by sevoflurane.

31 March 2020

1 reference

Evaluating the energetics of empty cavities and internal mutations in proteins

31 March 2020

1 reference

A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol.

31 March 2020

1 reference

Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue

31 March 2020

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Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor

31 March 2020

1 reference

Magnocellular nuclei of the basal forebrain: substrates of sleep and arousal regulation

31 March 2020

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inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1038/NRN2372

1 reference

18 August 2017

1 reference

PubMed ID

18425091