Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation (Q37142781)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18854315%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Alternate mRNA splicing in multiple human tryptase genes is predicted to regulate tetramer formation (English)

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15 January 2020

4

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15 January 2020

author name string

Nicole E Jackson

1

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15 January 2020

Hong-Wei Wang

2

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15 January 2020

Katherine J Bryant

3

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15 January 2020

Ahsan Husain

5

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15 January 2020

Ke Liu

6

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15 January 2020

Nicodemus Tedla

7

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15 January 2020

Paul S Thomas

8

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15 January 2020

Garry C King

9

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15 January 2020

Anusha Hettiaratchi

10

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15 January 2020

Jennifer Cairns

11

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15 January 2020

John E Hunt

12

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15 January 2020

language of work or name

English

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publication date

14 October 2008

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Journal of Biological Chemistry

15 January 2020

published in

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15 January 2020

volume

283

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15 January 2020

page(s)

34178-34187

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15 January 2020

issue

49

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Large-scale analysis of human alternative protein isoforms: pattern classification and correlation with subcellular localization signals

15 January 2020

cites work

1 reference

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The heterogeneity of mast cell tryptase from human lung and skin

6 September 2017

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Delta tryptase is expressed in multiple human tissues, and a recombinant form has proteolytic activity

6 September 2017

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Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells.

6 September 2017

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Alternative splicing and diversity of renal transporters

6 September 2017

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Structural requirements and mechanism for heparin-induced activation of a recombinant mouse mast cell tryptase, mouse mast cell protease-6: formation of active tryptase monomers in the presence of low molecular weight heparin

6 September 2017

1 reference

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The activation of synovial mast cells: modulation of histamine release by tryptase and chymase and their inhibitors

6 September 2017

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Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families

6 September 2017

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Potent selective nonpeptidic inhibitors of human lung tryptase.

6 September 2017

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Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft

6 September 2017

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Inhibitors of tryptase for the treatment of mast cell-mediated diseases

6 September 2017

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Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3

6 September 2017

1 reference

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Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

6 September 2017

1 reference

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Generation and analysis of 280,000 human expressed sequence tags

6 September 2017

1 reference

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The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis

6 September 2017

1 reference

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Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs

6 September 2017

1 reference

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The mast cell as a primary effector cell in the pathogenesis of asthma

6 September 2017

1 reference

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Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family

6 September 2017

1 reference

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Mitogenic responses mediated through the proteinase-activated receptor-2 are induced by expressed forms of mast cell alpha- or beta-tryptases

6 September 2017

1 reference

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Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6.

29 September 2017

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Tryptase inhibitors block allergen-induced airway and inflammatory responses in allergic sheep.

27 June 2018

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The effects of alternative splicing on transmembrane proteins in the mouse genome.

27 June 2018

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Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study

3 September 2018

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Diverse stability and catalytic properties of human tryptase alpha and beta isoforms are mediated by residue differences at the S1 pocket

3 September 2018

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Elevated serum concentrations of beta-tryptase, but not alpha-tryptase, in Sudden Infant Death Syndrome (SIDS). An investigation of anaphylactic mechanisms.

3 September 2018

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Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma

3 September 2018

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Identification and characterization of multiple forms of tryptase from human mast cells

3 September 2018

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Potent induction of a neutrophil and eosinophil-rich infiltrate in vivo by human mast cell tryptase: selective enhancement of eosinophil recruitment by histamine.

3 September 2018

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3 September 2018

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Tryptase from human pulmonary mast cells. Purification and characterization

3 September 2018

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12 December 2020

Antibody screening for secreted proteins expressed in Pichia pastoris

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12 December 2020

Mast cell responses in rheumatoid synovium. Association of the MCTC subset with matrix turnover and clinical progression

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12 December 2020

Recombinant human mast cell tryptase beta: stable expression in Pichia pastoris and purification of fully active enzyme

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12 December 2020

Identifiers

DOI

10.1074/JBC.M807553200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18854315%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

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15 January 2020

1 reference