Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury (Q37138010)

18 August 2017

Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury (English)

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18 August 2017

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4

Zena Werb

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author name string

Jung-Yu C Hsu

1

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18 August 2017

Robert McKeon

2

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18 August 2017

Staci Goussev

3

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18 August 2017

Zena Werb

4

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18 August 2017

Jung-Uek Lee

5

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18 August 2017

Alpa Trivedi

6

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18 August 2017

Linda J Noble-Haeusslein

7

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18 August 2017

language of work or name

English

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publication date

1 September 2006

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18 August 2017

Journal of Neuroscience

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18 August 2017

26

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18 August 2017

9841-9850

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18 August 2017

39

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describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2659718/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Role of intracellular S100A4 for migration of rat astrocytes

14 September 2017

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Regulation of matrix biology by matrix metalloproteinases

14 September 2017

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Reactive astrocytes protect tissue and preserve function after spinal cord injury

14 September 2017

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Regeneration beyond the glial scar

14 September 2017

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Blood‐spinal cord barrier after spinal cord injury: Relation to revascularization and wound healing

14 September 2017

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Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing

14 September 2017

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The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury

14 September 2017

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Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes

14 September 2017

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Inhibiting cell proliferation during formation of the glial scar: effects on axon regeneration in the CNS.

14 September 2017

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Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin

14 September 2017

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Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue

14 September 2017

1 reference

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Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events.

14 September 2017

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Comparison of matrix metalloproteinase expression during Wallerian degeneration in the central and peripheral nervous systems

14 September 2017

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Chondroitinase ABC promotes functional recovery after spinal cord injury

14 September 2017

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How matrix metalloproteinases regulate cell behavior

14 September 2017

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The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis

14 September 2017

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Metalloproteinases in biology and pathology of the nervous system.

14 September 2017

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Matrix metalloproteinase expression and inhibition after sciatic nerve axotomy

14 September 2017

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Modulating astrogliosis after neurotrauma

14 September 2017

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Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

14 September 2017

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Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

14 September 2017

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Identification of a neural stem cell in the adult mammalian central nervous system

14 September 2017

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Matrix metalloproteinase expression in an experimentally-induced DTH model of multiple sclerosis in the rat CNS.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Mechanisms of motor recovery after subtotal spinal cord injury: insights from the study of mice carrying a mutation (WldS) that delays cellular responses to injury

14 September 2017

1 reference

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Regeneration of adult axons in white matter tracts of the central nervous system

14 September 2017

1 reference

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Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5

14 September 2017

1 reference

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A sensitive and reliable locomotor rating scale for open field testing in rats

14 September 2017

1 reference

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The matrix-degrading metalloproteinases

14 September 2017

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Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes.

14 September 2017

1 reference

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Transplanted neural stem cells promote axonal regeneration through chronically denervated peripheral nerves.

14 September 2017

1 reference

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The responses of oligodendrocyte precursor cells, astrocytes and microglia to a cortical stab injury, in the brain

14 September 2017

1 reference

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Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia

14 September 2017

1 reference

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Oligodendrocyte-type 2 astrocyte progenitors use a metalloendoprotease to spread and migrate on CNS myelin

14 September 2017

1 reference

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Neurodegeneration in Striatum Induced by the Mitochondrial Toxin 3-Nitropropionic Acid: Role of Matrix Metalloproteinase-9 in Early Blood-Brain Barrier Disruption?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroitin sulfate proteoglycan.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Reactive astrocytes: cellular and molecular cues to biological function

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Local blockade of sodium channels by tetrodotoxin ameliorates tissue loss and long-term functional deficits resulting from experimental spinal cord injury.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood-brain barrier injury

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Use of serotonin immunocytochemistry as a marker of injury severity after experimental spinal trauma in rats

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Role of matrix metalloproteinases in delayed cortical responses after stroke.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Early profiles of axonal growth and astroglial response after spinal cord hemisection and implantation of Schwann cell-seeded guidance channels in adult rats.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Temporal and spatial distribution of growth-associated molecules and astroglial cells in the rat corticospinal tract during development

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Metalloproteinase-dependent predegeneration in vitro enhances axonal regeneration within acellular peripheral nerve grafts.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Requirement of functional ryanodine receptor type 3 for astrocyte migration.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Intermediate filaments regulate astrocyte motility.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Cellular and molecular mechanisms of glial scarring and progressive cavitation: in vivo and in vitro analysis of inflammation-induced secondary injury after CNS trauma.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Long-term effects of methylprednisolone following transection of adult rat spinal cord.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Injury-induced 92-kilodalton gelatinase and urokinase expression in rat brain.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Putative inhibitory extracellular matrix molecules at the dorsal root entry zone of the spinal cord during development and after root and sciatic nerve lesions.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659718

MMP-2 null mice exhibit an early onset and severe experimental autoimmune encephalomyelitis due to an increase in MMP-9 expression and activity

3 September 2018

1 reference

12 December 2020

The chondroitin sulfate proteoglycans neurocan and phosphacan are expressed by reactive astrocytes in the chronic CNS glial scar

1 reference

12 December 2020

Neurocan is upregulated in injured brain and in cytokine-treated astrocytes

1 reference

12 December 2020

1 reference

12 December 2020

Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan

1 reference

12 December 2020

Chondroitinase ABC enhances axonal regrowth through Schwann cell-seeded guidance channels after spinal cord injury

1 reference

12 December 2020

Spinal cord contusion in the rat: morphometric analyses of alterations in the spinal cord

1 reference

12 December 2020

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1 reference

12 December 2020

Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury

1 reference

12 December 2020

Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX

1 reference

12 December 2020

Matrix metalloproteinases degrade myelin basic protein

1 reference

12 December 2020

Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window

1 reference

12 December 2020

10.1523/JNEUROSCI.1993-06.2006

Identifiers

DOI

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18 August 2017

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18 August 2017

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