Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation. (Q37136357)

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12 March 2020

title

Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation (English)

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12 March 2020

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3

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12 March 2020

Judith Bovée

13

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12 March 2020

Alexander J. Lazar

14

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author name string

Marieke A de Graaff

1

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12 March 2020

Jamie S E Yu

2

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12 March 2020

Davis R Ingram

4

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12 March 2020

Theresa Nguyen

5

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12 March 2020

Jeffrey Juehui Liu

6

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12 March 2020

Svetlana Bolshakov

7

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12 March 2020

Károly Szuhai

8

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Keila E Torres

10

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12 March 2020

Dina Lev

11

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12 March 2020

Torsten O Nielsen

12

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12 March 2020

Neeta Somaiah

15

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12 March 2020

Pierre Åman

9

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12 March 2020

publication date

6 June 2016

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12 March 2020

published in

Laboratory Investigation

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12 March 2020

volume

96

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12 March 2020

issue

8

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12 March 2020

page(s)

885-894

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describes a project that uses

12 March 2020

DL-221

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/labinvest.2016.64

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cites work

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14 September 2017

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14 September 2017

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14 September 2017

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Efficacy of first-line doxorubicin and ifosfamide in myxoid liposarcoma

14 September 2017

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Myxoid liposarcoma-associated EWSR1-DDIT3 selectively represses osteoblastic and chondrocytic transcription in multipotent mesenchymal cells

14 September 2017

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NY-ESO-1 is a ubiquitous immunotherapeutic target antigen for patients with myxoid/round cell liposarcoma

14 September 2017

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Prognostic factors and metastatic patterns in primary myxoid/round-cell liposarcoma

14 September 2017

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

14 September 2017

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Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and casein kinase II inhibition as a potential treatment option.

14 September 2017

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Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

14 September 2017

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Clinicopathologic prognostic factors of pure myxoid liposarcoma of the extremities and trunk wall

14 September 2017

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Retracted: Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

14 September 2017

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Multifocal myxoid liposarcoma--metastasis or second primary tumor?: a molecular biological analysis

14 September 2017

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The TET family of proteins: functions and roles in disease

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with NFKBIZ.

14 September 2017

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FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E.

14 September 2017

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Relevance of translocation type in myxoid liposarcoma and identification of a novel EWSR1-DDIT3 fusion

14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases.

14 September 2017

1 reference

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Genomic cloning and localization of CTAG, a gene encoding an autoimmunogenic cancer-testis antigen NY-ESO-1, to human chromosome Xq28

14 September 2017

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The clinicopathologic spectrum of myxoid and round cell liposarcoma. A study of 95 cases

14 September 2017

1 reference

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Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

14 September 2017

1 reference

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CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

14 September 2017

1 reference

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Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11)

14 September 2017

1 reference

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Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Simultaneous molecular karyotyping and mapping of viral DNA integration sites by 25-color COBRA-FISH.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Diverse mechanisms of somatic structural variations in human cancer genomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis.

27 June 2018

1 reference

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Molecular aberrations of the G1-S checkpoint in myxoid and round cell liposarcoma

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

NY-ESO-1 (CTAG1B) expression in mesenchymal tumors.

27 June 2018

1 reference

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Localized and metastatic myxoid/round cell liposarcoma: clinical and molecular observations

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Detection of myxoid liposarcoma-associated FUS-DDIT3 rearrangement variants including a newly identified breakpoint using an optimized RT-PCR assay.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Functional mapping of receptor tyrosine kinases in myxoid liposarcoma.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Validation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarrays.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Midkine enhances soft-tissue sarcoma growth: a possible novel therapeutic target

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Identification of genes differentially expressed in TLS-CHOP carrying myxoid liposarcomas.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965313

Solitary fibrous tumor: a clinicopathological study of 110 cases and proposed risk assessment model.

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLABINVEST.2016.64

Histone deacetylase 1 and 2 in mesenchymal tumors

21 January 2018

1 reference

12 December 2020

Myxoid\round cell liposarcoma (MRCLS) revisited: an analysis of 418 primarily managed cases

1 reference

12 December 2020

Clinicopathologic prognostic factors in myxoid liposarcoma: a retrospective study of 49 patients with long-term follow-up

1 reference

12 December 2020

The cancer-testis antigen NY-ESO-1 is highly expressed in myxoid and round cell subset of liposarcomas

1 reference

12 December 2020

Monophasic and biphasic synovial sarcomas abundantly express cancer/testis antigen NY-ESO-1 but not MAGE-A1 or CT7

1 reference

12 December 2020

SV40-Mediated immortalization

1 reference

12 December 2020

Limited role of TP53 and TP53-related genes in myxoid liposarcoma

1 reference

12 December 2020

10.1038/LABINVEST.2016.64

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27270875%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27270875%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference