Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation. (Q37134376)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19131338%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation (English)

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19 January 2020

4

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19 January 2020

3

Patrick Trojer

1 reference

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19 January 2020

author name string

Shivani Garapaty

1

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19 January 2020

Chong-Feng Xu

2

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19 January 2020

Thomas A Neubert

5

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19 January 2020

Herbert H Samuels

6

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19 January 2020

language of work or name

English

0 references

publication date

8 January 2009

1 reference

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Journal of Biological Chemistry

19 January 2020

published in

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19 January 2020

volume

284

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19 January 2020

page(s)

7542-7552

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19 January 2020

issue

12

1 reference

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The BRG1 transcriptional coregulator

19 January 2020

cites work

1 reference

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Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development

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DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells

14 September 2017

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Negative regulation of the deacetylase SIRT1 by DBC1

14 September 2017

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DBC1 is a negative regulator of SIRT1

14 September 2017

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Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1

14 September 2017

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The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex

14 September 2017

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Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation

14 September 2017

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Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination

14 September 2017

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

14 September 2017

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Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells

14 September 2017

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14 September 2017

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Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components

14 September 2017

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The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection

14 September 2017

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PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex

14 September 2017

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Modulation of estrogen receptor alpha protein level and survival function by DBC-1.

14 September 2017

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Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex

14 September 2017

1 reference

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The role of chromatin during transcription

14 September 2017

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Chromatin modifications and their function

14 September 2017

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Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth

14 September 2017

1 reference

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Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases

14 September 2017

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DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation

14 September 2017

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

14 September 2017

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Regulation of insulin secretion and beta-cell mass by activating signal cointegrator 2

14 September 2017

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Role of the mediator complex in nuclear hormone receptor signaling.

14 September 2017

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Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.

14 September 2017

1 reference

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Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

14 September 2017

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Retention and repression: fates of hyperedited RNAs in the nucleus

14 September 2017

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Nuclear hormone receptor coregulator: role in hormone action, metabolism, growth, and development.

14 September 2017

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Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

14 September 2017

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Nuclear receptor recruitment of histone-modifying enzymes to target gene promoters

14 September 2017

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The nuclear hormone receptor coactivator NRC is a pleiotropic modulator affecting growth, development, apoptosis, reproduction, and wound repair

14 September 2017

1 reference

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Activation and interaction of ATF2 with the coactivator ASC-2 are responsive for granulocytic differentiation by retinoic acid

14 September 2017

1 reference

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EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

14 September 2017

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The BRCA2-EMSY connection: implications for breast and ovarian tumorigenesis

14 September 2017

1 reference

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Review of the in vivo functions of the p160 steroid receptor coactivator family

14 September 2017

1 reference

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Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

14 September 2017

1 reference

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Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

14 September 2017

1 reference

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RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition

14 September 2017

1 reference

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DBC2, a candidate for a tumor suppressor gene involved in breast cancer

14 September 2017

1 reference

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NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

14 September 2017

1 reference

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Combinatorial control of gene expression by nuclear receptors and coregulators

14 September 2017

1 reference

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Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

14 September 2017

1 reference

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A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein

14 September 2017

1 reference

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Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2

14 September 2017

1 reference

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The Ki-67 protein: fascinating forms and an unknown function

14 September 2017

1 reference

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Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator

14 September 2017

1 reference

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Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

Cloning and characterization of RAP250, a novel nuclear receptor coactivator

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo

14 September 2017

1 reference

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Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16)

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

Agonist and antagonist of retinoic acid receptors cause similar changes in gene expression and induce senescence-like growth arrest in MCF-7 breast carcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

p53-, SIRT1-, and PARP-1-independent downregulation of p21WAF1 expression in nicotinamide-treated cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

MLL core components give the green light to histone methylation.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

Null mutation of peroxisome proliferator-activated receptor-interacting protein in mammary glands causes defective mammopoiesis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658049

Interaction of MLL amino terminal sequences with menin is required for transformation

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19131338

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M805872200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19131338%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19131338%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference