Assessing the utility of intermediate phenotypes for genetic mapping of psychiatric disease (Q37126955)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

review article

1 reference

title

Assessing the utility of intermediate phenotypes for genetic mapping of psychiatric disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Jonathan Flint

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

3

Marcus Munafò

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

18 August 2017

language of work or name

1 reference

9 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

published in

Trends in Neurosciences

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

37

1 reference

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16 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

733-741

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

16 February 2020

cites work

1 reference

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Genome-wide association analysis identifies 13 new risk loci for schizophrenia

14 September 2017

1 reference

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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

14 September 2017

1 reference

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What psychiatric genetics has taught us about the nature of psychiatric illness and what is left to learn

14 September 2017

1 reference

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Power failure: why small sample size undermines the reliability of neuroscience

14 September 2017

1 reference

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Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia

14 September 2017

1 reference

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Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

14 September 2017

1 reference

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Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

14 September 2017

1 reference

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Seventy-five genetic loci influencing the human red blood cell

14 September 2017

1 reference

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Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world

14 September 2017

1 reference

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The fibroblast growth factor family: neuromodulation of affective behavior

14 September 2017

1 reference

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Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

14 September 2017

1 reference

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Common variants at 12q14 and 12q24 are associated with hippocampal volume

14 September 2017

1 reference

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Common variants at 12q15 and 12q24 are associated with infant head circumference

14 September 2017

1 reference

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Common variants at 6q22 and 17q21 are associated with intracranial volume

14 September 2017

1 reference

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Identification of common variants associated with human hippocampal and intracranial volumes

14 September 2017

1 reference

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Overlapping and segregating structural brain abnormalities in twins with schizophrenia or bipolar disorder

14 September 2017

1 reference

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High frequencies of de novo CNVs in bipolar disorder and schizophrenia

14 September 2017

1 reference

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Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Reduced sleep spindles and spindle coherence in schizophrenia: mechanisms of impaired memory consolidation?

14 September 2017

1 reference

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Genome-wide association study identifies five new schizophrenia loci

14 September 2017

1 reference

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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Exome sequencing supports a de novo mutational paradigm for schizophrenia.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Neurogenesis and affective disorders

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

New IBD genetics: common pathways with other diseases.

14 September 2017

1 reference

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Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

14 September 2017

1 reference

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Characterization of a novel interaction between Bcl-2 members Diva and Harakiri

14 September 2017

1 reference

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Genomics, type 2 diabetes, and obesity

14 September 2017

1 reference

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Analysing biological pathways in genome-wide association studies

14 September 2017

1 reference

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The GABAergic deficit hypothesis of major depressive disorder.

14 September 2017

1 reference

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Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

14 September 2017

1 reference

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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

14 September 2017

1 reference

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Hundreds of variants clustered in genomic loci and biological pathways affect human height

14 September 2017

1 reference

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Genetic variation in CACNA1C affects brain circuitries related to mental illness

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Biological, clinical and population relevance of 95 loci for blood lipids

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Common SNPs explain a large proportion of the heritability for human height

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Endophenotype: a conceptual analysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Structural abnormalities in gyri of the prefrontal cortex in individuals with schizophrenia and their unaffected siblings

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip

14 September 2017

1 reference

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

14 September 2017

1 reference

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Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

14 September 2017

1 reference

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Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

14 September 2017

1 reference

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Strong association of de novo copy number mutations with sporadic schizophrenia

14 September 2017

1 reference

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A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

14 September 2017

1 reference

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Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

14 September 2017

1 reference

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Variations in DNA elucidate molecular networks that cause disease

14 September 2017

1 reference

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Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia

14 September 2017

1 reference

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Endophenotypes in the genetic analyses of mental disorders.

14 September 2017

1 reference

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Strong association of de novo copy number mutations with autism

14 September 2017

1 reference

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The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration

14 September 2017

1 reference

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The endophenotype concept in psychiatric genetics

14 September 2017

1 reference

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Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis

14 September 2017

1 reference

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Mendelian randomization: prospects, potentials, and limitations

14 September 2017

1 reference

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Glutamate and depression: clinical and preclinical studies

14 September 2017

1 reference

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The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)

14 September 2017

1 reference

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Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

14 September 2017

1 reference

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The endophenotype concept in psychiatry: etymology and strategic intentions

14 September 2017

1 reference

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Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

14 September 2017

1 reference

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The corticosteroid receptor hypothesis of depression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Role of the serotonergic system in the pathogenesis of major depression and suicidal behavior

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

COMORBIDITY OF ANXIETY AND UNIPOLAR MOOD DISORDERS

14 September 2017

1 reference

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A molecular and cellular theory of depression

14 September 2017

1 reference

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Comorbidity of DSM-III-R major depressive disorder in the general population: results from the US National Comorbidity Survey

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey

14 September 2017

1 reference

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Are all significant P values created equal? The analogy between diagnostic tests and clinical research

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Impaired intellect and memory: a missing link between genetic risk and schizophrenia?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples

27 June 2018

1 reference

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The molecular genetics of schizophrenia: an update

27 June 2018

1 reference

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Comorbidity and boundaries of affective disorders with anxiety disorders and substance misuse: results of an international task force

27 June 2018

1 reference

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The role of the major histocompatibility complex region in cognition and brain structure: a schizophrenia GWAS follow-up.

27 June 2018

1 reference

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A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval

3 September 2018

1 reference

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Distinguishing true from false positives in genomic studies: p values

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

The impact of the CACNA1C gene polymorphism on frontolimbic function in bipolar disorder.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Effects of a CACNA1C genotype on attention networks in healthy individuals

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

A de novo paradigm for mental retardation.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Brain function in carriers of a genome-wide supported bipolar disorder variant.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Genetic overlap between episodic memory deficits and schizophrenia: results from the Maudsley Twin Study.

3 September 2018

1 reference

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The CACNA1C risk variant for bipolar disorder influences limbic activity.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Heritability of changes in brain volume over time in twin pairs discordant for schizophrenia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Diagnostic co-morbidity in 2300 psychiatric out-patients presenting for treatment evaluated with a semi-structured diagnostic interview.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Endophenotypes in psychiatric genetics.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Generalized Anxiety Disorder and major depressive disorder comorbidity in the National Survey of Mental Health and Well-Being.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

12-Month comorbidity patterns and associated factors in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Recognition accuracy and response bias to happy and sad facial expressions in patients with major depression.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Longitudinal assessment of premorbid cognitive functioning in patients with schizophrenia through examination of standardized scholastic test performance.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

The strawberry notch gene functions with Notch in common developmental pathways.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4961231

Increased exonic de novo mutation rate in individuals with schizophrenia

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25216981

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prevalence of anxiety disorders comorbidity in bipolar depression, unipolar depression and dysthymia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25216981

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comorbidity of anxiety, phobia, compulsion and depression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25216981

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TINS.2014.08.007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216981%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference