Small molecule bradykinin B1 receptor antagonists as potential therapeutic agents for pain (Q37125197)

18 August 2017

1 reference

title

Small molecule bradykinin B1 receptor antagonists as potential therapeutic agents for pain (English)

1 reference

18 August 2017

Jian Jeffrey Chen

1

1 reference

PubMed ID

18381126

18 August 2017

Kaustav Biswas

series ordinal

2

1 reference

18 August 2017

1 January 2008

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Progress in medicinal chemistry

18 August 2017

1 reference

18 August 2017

46

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18 August 2017

173-204

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Bradykinin receptor ligands: therapeutic perspectives

18 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Inflammatory pain: kinins and antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Targeting the bradykinin B1 receptor to reduce pain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

1 reference

7 January 2021

Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Evidence for the participation of kinins in Freund's adjuvant-induced inflammatory and nociceptive responses in kinin B1 and B2 receptor knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Reduced Nerve Injury-Induced Neuropathic Pain in Kinin B1 Receptor Knock-Out Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Absence of diabetic hyperalgesia in bradykinin B1 receptor-knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Targeted disruption of a B2 bradykinin receptor gene in mice eliminates bradykinin action in smooth muscle and neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Effect of high salt intake in mutant mice lacking bradykinin-B2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Bradykinin antagonists: discovery and development

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Bradykinin and inflammatory pain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Antinociceptive activity of the bradykinin B1 and B2 receptor antagonists, des-Arg9, [Leu8]-BK and HOE 140, in two models of persistent hyperalgesia in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Substance P and capsaicin-induced mechanical hyperalgesia in the rat knee joint; the involvement of bradykinin B1 and B2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Kinin B1 receptor antagonists inhibit diabetes-induced hyperalgesia in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

The bradykinin B1 receptor antagonist B9858 inhibits a nociceptive spinal reflex in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Switching of bradykinin-mediated nociception following partial sciatic nerve injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Increased mRNA expression of the B1 and B2 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Amelioration of hyperalgesia by kinin receptor antagonists or kininogen deficiency in chronic constriction nerve injury in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Kinin receptors: functional aspects.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

2,3-diaminopyridine bradykinin B1 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

SSR240612 [(2R)-2-[((3R)-3-(1,3-benzodioxol-5-yl)-3-[[(6-methoxy-2-naphthyl)sulfonyl]amino]propanoyl)amino]-3-(4-[[2R,6S)-2,6-dimethylpiperidinyl]methyl]phenyl)-N-isopropyl-N-methylpropanamide hydrochloride], a new nonpeptide antagonist of the brady

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Antinociceptive pharmacology of N-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[[(4-methoxy-2,6-dimethylphenyl) sulfonyl]methylamino]ethoxy]-N-methylacetamide, fumarate (LF22-0542), a novel nonpeptidic bradykinin B1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Receptors for kinins in the human isolated umbilical vein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Benzodiazepines as Potent and Selective Bradykinin B1 Antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

L-745,337: a selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Effect of novel selective non-peptide kinin B1 receptor antagonists on mouse pleurisy induced by carrageenan

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Inhibition of acute nociceptive responses in rat spinal cord by a bradykinin B1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Analgesic efficacy of bradykinin B1 antagonists in a murine bone cancer pain model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Antihyperalgesic activity of a novel nonpeptide bradykinin B1 receptor antagonist in transgenic mice expressing the human B1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Generation and characterization of a humanized bradykinin B1 receptor mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Cloning and pharmacological characterization of a rabbit bradykinin B1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Molecular cloning and expression of rat bradykinin B1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Development of orally bioavailable and CNS penetrant biphenylaminocyclopropane carboxamide bradykinin B1 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Potent nonpeptide antagonists of the bradykinin B1 receptor: structure-activity relationship studies with novel diaminochroman carboxamides.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

A new generation of bradykinin antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Effects of a selective bradykinin B1 receptor antagonist on increased plasma extravasation in streptozotocin-induced diabetic rats: distinct vasculopathic profile of major key organs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

A new class of bradykinin 1 receptor antagonists containing the piperidine acetic acid tetralin core

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Discovery of a potent, non-peptide bradykinin B1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Binding modes of dihydroquinoxalinones in a homology model of bradykinin receptor 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Potent and orally bioavailable non-peptide antagonists at the human bradykinin B(1) receptor based on a 2-alkylamino-5-sulfamoylbenzamide core

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

2,3-Diaminopyridine as a platform for designing structurally unique nonpeptide bradykinin B1 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Bradykinin B1 antagonists: SAR studies in the 2,3-diaminopyridine series

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Bioactivation of 2,3-diaminopyridine-containing bradykinin B1 receptor antagonists: irreversible binding to liver microsomal proteins and formation of glutathione conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

5-Piperazinyl pyridine carboxamide bradykinin B1 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

Cyclopropylamino acid amide as a pharmacophoric replacement for 2,3-diaminopyridine. Application to the design of novel bradykinin B1 receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

A possible common pharmacophore in the non-peptide antagonists of the bradykinin B1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2807%2900004-5

7 January 2021

10.1016/S0079-6468(07)00004-5

Identifiers

DOI

1 reference

18 August 2017

1 reference

PubMed ID

18381126