An approach to achieve long-term expression in skin gene therapy (Q37109093)

18 August 2017

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title

An approach to achieve long-term expression in skin gene therapy (English)

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18 August 2017

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Jean-Philippe Therrien

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1

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18 August 2017

Wolfgang Pfützner

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2

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18 August 2017

Jonathan C Vogel

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3

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18 August 2017

language of work or name

English

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publication date

1 January 2008

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18 August 2017

Toxicologic Pathology

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18 August 2017

36

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18 August 2017

1

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18 August 2017

104-111

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Liposome-medicated gene transfer and expression via the skin

18 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Complete restoration of glucocerebrosidase deficiency in Gaucher fibroblasts using a bicistronic MDR retrovirus and a new selection strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Genetic correction of DNA repair-deficient/cancer-prone xeroderma pigmentosum group C keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Label-retaining cells in human embryonic and fetal epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Epidermal stem cells have the potential to assist in healing damaged tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Development and characterization of a recombinant truncated type VII collagen "minigene". Implication for gene therapy of dystrophic epidermolysis bullosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Corrective gene transfer in the human skin disorder lamellar ichthyosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Corrective transduction of human epidermal stem cells in laminin-5-dependent junctional epidermolysis bullosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Systemic distribution of apolipoprotein E secreted by grafts of epidermal keratinocytes: implications for epidermal function and gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

A model of corrective gene transfer in X-linked ichthyosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Towards gene therapy for haemophilia B using primary human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Fibroblasts show more potential as target cells than keratinocytes in COL7A1 gene therapy of dystrophic epidermolysis bullosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Epidermal "turnover time"--a re-examination

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

The multidrug resistance P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Correction of steroid sulfatase deficiency by gene transfer into basal cells of tissue-cultured epidermis from patients with recessive X-linked ichthyosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Gene transfer into cultured human epidermis and its transplantation onto immunodeficient mice: an experimental model for somatic gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Cutaneous gene transfer for skin and systemic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Hair follicle stem cells: their location, role in hair cycle, and involvement in skin tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Retroviral transfer of human MDR1 gene to hematopoietic cells: effects of drug selection and of transcript splicing on expression of encoded P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Drug selection of MDR1-transduced hematopoietic cells ex vivo increases transgene expression and chemoresistance in reconstituted bone marrow in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Atrial natriuretic peptide gene delivery reduces stroke-induced mortality rate in Dahl salt-sensitive rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Correction in trans for Fabry disease: expression, secretion and uptake of alpha-galactosidase A in patient-derived cells driven by a high-titer recombinant retroviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Correction of lysosomal storage in the liver and spleen of MPS VII mice by implantation of genetically modified skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Stable nonviral genetic correction of inherited human skin disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Sustained production of human transferrin by transduced fibroblasts implanted into athymic mice: a model for somatic gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Selection of keratinocytes transduced with the multidrug resistance gene in an in vitro skin model presents a strategy for enhancing gene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Reconstruction of human epidermis on de-epidermized dermis: Expression of differentiation-specific protein markers and lipid composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Nonviral transfer of genes to pig primary keratinocytes. Induction of angiogenesis by composite grafts of modified keratinocytes overexpressing VEGF driven by a keratin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

BP180 gene delivery in junctional epidermolysis bullosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Sustained phenotypic reversion of junctional epidermolysis bullosa dog keratinocytes: Establishment of an immunocompetent animal model for cutaneous gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Retroviral Coexpression of a Multidrug Resistance Gene (MDR1) and Humanα-Galactosidase A for Gene Therapy of Fabry Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Drug-selected co-expression of P-glycoprotein and gp91 in vivo from an MDR1-bicistronic retrovirus vector Ha-MDR-IRES-gp91.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Corrective gene transfer of keratinocytes from patients with junctional epidermolysis bullosa restores assembly of hemidesmosomes in reconstructed epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

The natriuretic-peptide family

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Introduction of foreign genes into tissues of living mice by DNA-coated microprojectiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Intravenously injected human fibroblasts home to skin wounds, deliver type VII collagen, and promote wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

Co-expression of human adenosine deaminase and multidrug resistance using a bicistronic retroviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623307312705

21 January 2018

Identifiers

DOI

10.1177/0192623307312705

1 reference

18 August 2017

1 reference