Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients (Q37106010)

18 August 2017

Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients (English)

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18 August 2017

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8

Hermann Haller

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18 August 2017

Philipp Kümpers

1

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18 August 2017

Alexander Lukasz

2

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18 August 2017

Sascha David

3

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18 August 2017

Rüdiger Horn

4

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18 August 2017

Carsten Hafer

5

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18 August 2017

Robert Faulhaber-Walter

6

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18 August 2017

Danilo Fliser

7

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18 August 2017

Jan T Kielstein

9

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18 August 2017

21 November 2008

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18 August 2017

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18 August 2017

12

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18 August 2017

6

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18 August 2017

R147

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https://scigraph.springernature.com/pub.10.1186/cc7130

18 August 2017

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cites work

Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays

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A prospective, observational study of soluble FLT-1 and vascular endothelial growth factor in sepsis

14 September 2017

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Admission angiopoietin levels in children with septic shock.

14 September 2017

1 reference

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Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome

14 September 2017

1 reference

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Mechanisms of sepsis-induced organ dysfunction

14 September 2017

1 reference

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Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1

14 September 2017

1 reference

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Pulmonary artery catheter versus pulse contour analysis: a prospective epidemiological study

14 September 2017

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Angiopoietins: a link between angiogenesis and inflammation.

14 September 2017

1 reference

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Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells

14 September 2017

1 reference

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Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality

14 September 2017

1 reference

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Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

14 September 2017

1 reference

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Bench-to-bedside review: sepsis is a disease of the microcirculation

14 September 2017

1 reference

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Pulmonary endothelium in acute lung injury: from basic science to the critically ill.

14 September 2017

1 reference

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Endothelium as an organ system

14 September 2017

1 reference

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Hypoxic regulation of angiopoietin-2 expression in endothelial cells.

14 September 2017

1 reference

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14 September 2017

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The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Thrombin induces increased expression and secretion of angiopoietin-2 from human umbilical vein endothelial cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Hypoxia-inducible angiopoietin-2 expression is mimicked by iodonium compounds and occurs in the rat brain and skin in response to systemic hypoxia and tissue ischemia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

APACHE II: a severity of disease classification system

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Assessment of cardiac preload and extravascular lung water by single transpulmonary thermodilution

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-1 protects the adult vasculature against plasma leakage.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-2 predicts disease-free survival after allogeneic stem cell transplantation in patients with high-risk myeloid malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Regulation of angiopoietin expression by bacterial lipopolysaccharide.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Protective role of angiopoietin-1 in endotoxic shock.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Vascular endothelial growth factor in severe sepsis and septic shock

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646310

Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway

20 October 2018

1 reference

12 December 2020

Vascular endothelial growth factor is increased during the first 48 hours of human septic shock and correlates with vascular permeability

1 reference

12 December 2020

Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients

1 reference

12 December 2020

Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC7130

1 reference

18 August 2017

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18 August 2017

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