Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease (Q37099657)

18 August 2017

Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease (English)

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18 August 2017

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Kirill Bersuker

1

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18 August 2017

Mark S Hipp

2

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18 August 2017

Barbara Calamini

3

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18 August 2017

Richard I Morimoto

4

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18 August 2017

Ron R Kopito

5

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18 August 2017

language of work or name

English

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publication date

9 July 2013

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Journal of Biological Chemistry

18 August 2017

6

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based on heuristic

inferred from page(s)

published in

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18 August 2017

288

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18 August 2017

33

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18 August 2017

23633-23638

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describes a project that uses

18 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3745309/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

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Poly-glutamine expanded huntingtin dramatically alters the genome wide binding of HSF1.

14 September 2017

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Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin

14 September 2017

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Tracking protein aggregation and mislocalization in cells with flow cytometry

14 September 2017

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Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease

14 September 2017

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The heat shock response: systems biology of proteotoxic stress in aging and disease

14 September 2017

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Small-molecule proteostasis regulators for protein conformational diseases

14 September 2017

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Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease

14 September 2017

1 reference

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BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

14 September 2017

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Protein folding in the cytoplasm and the heat shock response

14 September 2017

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Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases

14 September 2017

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

14 September 2017

1 reference

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Protein aggregation and neurodegenerative disease

14 September 2017

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Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

14 September 2017

1 reference

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

14 September 2017

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

14 September 2017

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Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells

14 September 2017

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17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

14 September 2017

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The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response

29 September 2017

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Firefly luciferase mutants as sensors of proteome stress

29 September 2017

1 reference

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Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

3 September 2018

1 reference

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Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

3 September 2018

1 reference

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Experimental demonstration of a universally valid error–disturbance uncertainty relation in spin measurements

3 September 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.C113.481945

21 January 2018

Identifiers

DOI

10.1074/JBC.C113.481945

1 reference

18 August 2017

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18 August 2017

1 reference