Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity (Q37088914)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

1 reference

1

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1 March 2020

author name string

Jon T Giles

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Michelle L Ols

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Herbert G Bull

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Felipe Andrade

5

1 reference

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1 March 2020

Antony Rosen

6

1 reference

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1 March 2020

language of work or name

English

0 references

publication date

1 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

1 March 2020

published in

1 reference

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1 March 2020

volume

5

1 reference

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1 March 2020

issue

186

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1 March 2020

page(s)

186ra65

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Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis

1 March 2020

cites work

1 reference

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Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

29 September 2017

1 reference

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N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.

29 September 2017

1 reference

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Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis.

29 September 2017

1 reference

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Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

29 September 2017

1 reference

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Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation

29 September 2017

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Autoantigens in systemic autoimmunity: critical partner in pathogenesis

29 September 2017

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Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis.

29 September 2017

1 reference

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Histone deimination as a response to inflammatory stimuli in neutrophils.

29 September 2017

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Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis

29 September 2017

1 reference

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Structural basis for Ca(2+)-induced activation of human PAD4

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

Unique conformation of cancer autoantigen B23 in hepatoma: a mechanism for specificity in the autoimmune response

29 September 2017

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Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes

29 September 2017

1 reference

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Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

29 September 2017

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How to read radiographs according to the Sharp/van der Heijde method.

29 September 2017

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

Ionized calcium in body fluids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

Rheumatoid arthritis-specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

Sphingosine mobilizes intracellular calcium in human neutrophils

27 June 2018

1 reference

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Human recombinant interferon gamma enhances neonatal polymorphonuclear leukocyte activation and movement, and increases free intracellular calcium

27 June 2018

1 reference

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Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3740946

Serum IgG antibodies to peptidylarginine deiminase 4 in rheumatoid arthritis and associations with disease severity

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23698378

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prevalence and significance of anti-peptidylarginine deiminase 4 antibodies in rheumatoid arthritis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23698378

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Serum IgG antibodies to peptidylarginine deiminase 4 predict radiographic progression in patients with rheumatoid arthritis treated with tumour necrosis factor-alpha blocking agents

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23698378

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.3005370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23698378%20AND%20SRC:MED&resulttype=core&format=json