Competitive antagonism of glycine at the N-methyl-d-aspartate (NMDA) receptor (Q37076226)

18 August 2017

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title

Competitive antagonism of glycine at the N-methyl-D-aspartate (NMDA) receptor (English)

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18 August 2017

Competitive antagonism of glycine at the N-methyl-d-aspartate (NMDA) receptor (English)

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

3 December 2022

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

3 December 2022

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

3 December 2022

author name string

J. E. Huettner

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1824750

3 December 2022

language of work or name

English

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publication date

1 January 1991

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full work available at URL

18 August 2017

https://api.elsevier.com/content/article/PII:000629529190004O?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

https://api.elsevier.com/content/article/PII:000629529190004O?httpAccept=text/plain

3 December 2022

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

3 December 2022

published in

Biochemical Pharmacology

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18 August 2017

41

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18 August 2017

1

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18 August 2017

9-16

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Glutamate activates multiple single channel conductances in hippocampal neurons.

18 August 2017

2

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

N-methyl-D-aspartate-activated channels of mouse central neurones in magnesium-free solutions.

3 December 2022

3

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones

3 December 2022

4

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Agonist- and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo III.

3 December 2022

5

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture

3 December 2022

6

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine potentiates the NMDA response in cultured mouse brain neurons

3 December 2022

7

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus.

3 December 2022

8

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes

3 December 2022

9

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortex

3 December 2022

10

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

3 December 2022

11

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Calcium overload in selectively vulnerable neurons of the hippocampus during and after ischemia: an electron microscopy study in the rat.

3 December 2022

12

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist.

3 December 2022

13

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Ionic dependence of glutamate neurotoxicity

3 December 2022

14

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

N-methyl-D-aspartate antagonists: ready for clinical trial in brain ischemia?

3 December 2022

15

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters

3 December 2022

16

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Excitatory amino acid receptors in the vertebrate central nervous system

3 December 2022

17

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Inhibition of motoneurones by iontophoresis of glycine.

3 December 2022

19

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

The hyperpolarization of spinal motoneurones by glycine and related amino acids.

3 December 2022

20

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA

3 December 2022

21

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Functional chloride channels by mammalian cell expression of rat glycine receptor subunit

3 December 2022

22

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex

3 December 2022

23

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine reverses antagonism of N-methyl-D-aspartate (NMDA) by 1-hydroxy-3-aminopyrrolidone-2 (HA-966) but not by D-2-amino-5-phosphonovalerate (D-AP5) on rat cortical slices

3 December 2022

24

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices

3 December 2022

25

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo

3 December 2022

26

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Modulation of glutamate receptors by phencyclidine and glycine in the rat cerebellum: cGMP increase in vivo

3 December 2022

27

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

In vivo modulation of the N-methyl-D-aspartate receptor complex by D-serine: potentiation of ongoing neuronal activity as evidenced by increased cerebellar cyclic GMP

3 December 2022

28

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Biochemical evidence that glycine allosterically regulates an NMDA receptor-coupled ion channel

3 December 2022

29

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine

3 December 2022

30

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine potentiates N-methyl-D-aspartate-induced [3H]TCP binding to rat cortical membranes

3 December 2022

31

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.

3 December 2022

32

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Differential modulation of [3H]TCP binding to the NMDA receptor by L-glutamate and glycine.

3 December 2022

33

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine modulation of the phencyclidine binding site in mammalian brain

3 December 2022

34

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist

3 December 2022

35

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Ketamine and phencyclidine cause a voltage-dependent block of responses to L-aspartic acid.

3 December 2022

36

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels

3 December 2022

37

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Kinetic characterization of the phencyclidine-N-methyl-D-aspartate receptor interaction: evidence for a steric blockade of the channel

3 December 2022

38

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes

3 December 2022

39

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA

3 December 2022

40

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons.

3 December 2022

42

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists

3 December 2022

43

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Indole-2-carboxylic acid: a competitive antagonist of potentiation by glycine at the NMDA receptor

3 December 2022

45

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Kinetics of unliganded acetylcholine receptor channel gating

3 December 2022

46

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Studies of the inter-relationship between cerebrospinal fluid and plasma amino acid concentrations in normal individuals.

3 December 2022

48

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Free and conjugated amino acids in human CSF: influence of age and sex.

3 December 2022

49

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

The uptake and release of putative amino acid neurotransmitters

3 December 2022

50

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

What confers specificity on glycine for its receptor site?

3 December 2022

51

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine.

3 December 2022

52

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine

3 December 2022

55

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes

3 December 2022

56

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Structural requirements for activation of the glycine coagonist site of N-methyl-D-aspartate receptors expressed in Xenopus oocytes

3 December 2022

57

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Structural requirements for activation of the glycine receptor that modulates the N-methyl-D-aspartate operated ion channel

3 December 2022

58

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Determination of the Equilibrium Dissociation Constants and Number of Glycine Binding Sites in Several Areas of the Rat Central Nervous System, Using a Sodium-Independent System

3 December 2022

59

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

1-Aminocyclopropane-1-carboxylic acid (ACC) mimics the effects of glycine on the NMDA receptor ion channel

3 December 2022

60

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

1-Aminocyclopropane carboxylic acid: a potent and selective ligand for the glycine modulatory site of the N-methyl-D-aspartate receptor complex

3 December 2022

61

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor

3 December 2022

62

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Cycloleucine competitively antagonizes the strychnine-insensitive glycine receptor

3 December 2022

63

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor

3 December 2022

64

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Kynurenic acid inhibits synaptic and acidic amino acid-induced responses in the rat hippocampus and spinal cord

3 December 2022

65

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Mg2+-like selective antagonism of excitatory amino acid-induced responses by α,ε-diaminopimelic acid, D-α-maminoadipate and HA-966 in isolated spinal cord of frog and immature rat

3 December 2022

66

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

A comparison of excitatory amino acid antagonists acting at primary afferent C fibres and motoneurones of the isolated spinal cord of the rat.

3 December 2022

67

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.

3 December 2022

69

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor

3 December 2022

71

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site

3 December 2022

72

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine reverses the effect of HA-966 on NMDA responses in cultured rat cortical neurons and in chick retina

3 December 2022

73

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

NMDA receptor antagonists that bind to the strychnine-insensitive glycine site and inhibit NMDA-induced Ca2+ fluxes and [3H]GABA release.

3 December 2022

75

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors

3 December 2022

76

1 reference

https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Antagonists of NMDA-activated current in cortical neurons: competition with glycine and blockade of open channels

3 December 2022

77

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors

3 December 2022

78

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Antagonist profile of 6,7-dichloro-3-hydroxy-2-quinoxalinecarboxylate at excitatory amino acid receptors in the neonatal rat spinal cord

3 December 2022

80

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

6,7-Dichloro-3-hydroxy-2-quinoxalinecarboxylic acid is a relatively potent antagonist at NMDA and kainate receptors

3 December 2022

81

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

6,7-Dinitro-quinoxaline-2,3-dion and 6-nitro,7-cyano-quinoxaline-2,3-dion antagonise responses to NMDA in the rat spinal cord via an action at the strychnine-insensitive glycine receptor

3 December 2022

82

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Quinoxaline derivatives are high-affinity antagonists of the NMDA receptor-associated glycine sites

3 December 2022

83

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) antagonizes NMDA-evoked [3H]GABA release from cultured cortical neurons via an inhibitory action at the strychnine-insensitive glycine site

3 December 2022

84

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Anticonvulsant properties of 3-hydroxy-2-quinoxalinecarboxylic acid, a newly found antagonist of excitatory amino acids.

3 December 2022

85

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine maintains excitement

3 December 2022

90

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine modulation of the NMDA receptor/channel complex

3 December 2022

91

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Indolpyruvic acid administration increases the brain content of kynurenic acid. Is this a new avenue to modulate excitatory amino acid receptors in vivo?

3 December 2022

92

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Rat brain slices produce and liberate kynurenic acid upon exposure to L-kynurenine

3 December 2022

93

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection

3 December 2022

94

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

Glycine reverses 7-Cl kynurenate blockade of glutamate neurotoxicity in cell culture

3 December 2022

95

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https://api.crossref.org/works/10.1016/0006-2952(91)90004-O

3 December 2022

Identifiers

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18 August 2017

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