Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma. (Q37069238)

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scientific article published on January 2009

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English	Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma.	scientific article published on January 2009

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scholarly article

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19 January 2020

Phase I and pharmacokinetic studies of erlotinib administered concurrently with radiotherapy for children, adolescents, and young adults with high-grade glioma (English)

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19 January 2020

radiation therapy

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1 reference

based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

7

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19 January 2020

Raelene Endersby

9

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19 January 2020

author name string

Alberto Broniscer

1

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19 January 2020

Suzanne J Baker

2

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19 January 2020

Clinton F Stewart

3

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19 January 2020

Thomas E Merchant

4

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19 January 2020

Fred H Laningham

5

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19 January 2020

Paula Schaiquevich

6

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19 January 2020

E Brannon Morris

8

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19 January 2020

David W Ellison

10

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19 January 2020

Amar Gajjar

11

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19 January 2020

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1 January 2009

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19 January 2020

Clinical Cancer Research

1 reference

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19 January 2020

15

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19 January 2020

701-707

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19 January 2020

2

1 reference

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19 January 2020

Phase 2 study of temozolomide in children and adolescents with recurrent central nervous system tumors: a report from the Children's Oncology Group

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Lessons learned in the development of targeted therapy for malignant gliomas.

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Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain

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29 September 2017

Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma

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29 September 2017

Phase II trial of temozolomide in children with recurrent high-grade glioma.

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

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29 September 2017

Phase II clinical trial data with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) in non-small-cell lung cancer.

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

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29 September 2017

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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29 September 2017

Supratentorial high-grade astrocytoma and diffuse brainstem glioma: two challenges for the pediatric oncologist

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29 September 2017

High frequency of mutations of the PIK3CA gene in human cancers

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29 September 2017

Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study

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29 September 2017

Malignant glioma: genetics and biology of a grave matter.

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29 September 2017

Pediatric high-grade astrocytomas show chromosomal imbalances distinct from adult cases

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29 September 2017

Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood

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29 September 2017

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design

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29 September 2017

Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children

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27 June 2018

Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations.

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27 July 2018

Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors.

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4 September 2018

Plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite OSI-420.

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4 September 2018

Rarity of PTEN deletions and EGFR amplification in malignant gliomas of childhood: results from the Children's Cancer Group 945 cohort.

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4 September 2018

PIK3CA gene mutations in pediatric and adult glioblastoma multiforme.

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Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.

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4 September 2018

Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib

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4 September 2018

PIK3CA mutations in glioblastoma multiforme.

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4 September 2018

EGFR tyrosine kinase domain mutations in human gliomas

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4 September 2018

Clinical utility of fluorescence in situ hybridization (FISH) in nonbrainstem glioblastomas of childhood.

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4 September 2018

Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo

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4 September 2018

The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner.

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4 September 2018

Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies

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4 September 2018

Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies

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12 December 2020

based on heuristic

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Effects of smoking on the pharmacokinetics of erlotinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147777

12 December 2020

based on heuristic

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Phase I targeted combination trial of sorafenib and erlotinib in patients with advanced solid tumors

1 reference

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12 December 2020

based on heuristic

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Identifiers

10.1158/1078-0432.CCR-08-1923

1 reference

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19 January 2020

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19147777%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19147777%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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