S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response. (Q37058729)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199853%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

review article

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title

S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199853%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1

Danyelle M Townsend

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199853%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

1 December 2007

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Molecular Interventions: pharmacological perspectives from biology, chemistry and genomics

1 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199853%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

7

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1 January 2020

issue

6

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1 January 2020

page(s)

313-324

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Regulation of JNK signaling by GSTp

1 January 2020

cites work

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12 December 2020

The protein disulphide-isomerase family: unravelling a string of folds

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12 December 2020

Nitric oxide-induced S-glutathionylation and inactivation of glyceraldehyde-3-phosphate dehydrogenase

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12 December 2020

Oxidative stress indicators are elevated in de novo Parkinson's disease patients.

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Novel application of S-nitrosoglutathione-Sepharose to identify proteins that are potential targets for S-nitrosoglutathione-induced mixed-disulphide formation

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The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance

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Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases

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12 December 2020

Oxidant-induced S-glutathiolation inactivates protein kinase C-alpha (PKC-alpha): a potential mechanism of PKC isozyme regulation

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12 December 2020

PERK mediates cell-cycle exit during the mammalian unfolded protein response

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12 December 2020

Domains b' and a' of protein disulfide isomerase fulfill the minimum requirement for function as a subunit of prolyl 4-hydroxylase. The N-terminal domains a and b enhances this function and can be substituted in part by those of ERp57.

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12 December 2020

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

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12 December 2020

Glutathiolation of the proteasome is enhanced by proteolytic inhibitors

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12 December 2020

Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis

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12 December 2020

Reversible glutathionylation regulates actin polymerization in A431 cells

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12 December 2020

Molecular chaperones in the cytosol: from nascent chain to folded protein

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12 December 2020

c-Jun regulation by S-glutathionylation

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12 December 2020

S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase: role of thiol oxidation and catalysis by glutaredoxin

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12 December 2020

Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes

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12 December 2020

Proteomics reveals protein profile changes in doxorubicin--treated MCF-7 human breast cancer cells.

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12 December 2020

Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function

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12 December 2020

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

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12 December 2020

Reversible glutathionylation of complex I increases mitochondrial superoxide formation

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12 December 2020

Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status

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12 December 2020

Prognostic significance of tumor oxygenation in humans.

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12 December 2020

Cancer drugs, genetic variation and the glutathione-S-transferase gene family

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12 December 2020

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

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12 December 2020

Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease

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12 December 2020

Nitric oxide and reactive oxygen species in Parkinson's disease

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12 December 2020

Modulation of the redox state of tubulin by the glutathione/glutaredoxin reductase system

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12 December 2020

Oxidative protein folding in eukaryotes: mechanisms and consequences

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12 December 2020

The identification of a reaction site of glutathione mixed-disulphide formation on gammaS-crystallin in human lens

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12 December 2020

Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with pi GST.

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12 December 2020

Oxidative inhibition of human soluble catechol-O-methyltransferase

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12 December 2020

Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug

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12 December 2020

S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells.

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12 December 2020

Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain

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12 December 2020

Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE.

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12 December 2020

High ER stress in beta-cells stimulates intracellular degradation of misfolded insulin

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12 December 2020

S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

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12 December 2020

Misfolded proteins, endoplasmic reticulum stress and neurodegeneration

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12 December 2020

Enhanced dephosphorylation of cAMP-dependent protein kinase by oxidation and thiol modification

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12 December 2020

Regulation of mitochondrial NADP+-dependent isocitrate dehydrogenase activity by glutathionylation

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12 December 2020

Reversible silencing of CFTR chloride channels by glutathionylation

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12 December 2020

Glutaredoxin: role in reversible protein s-glutathionylation and regulation of redox signal transduction and protein translocation

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12 December 2020

Affinity of S100A1 protein for calcium increases dramatically upon glutathionylation

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12 December 2020

Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family

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12 December 2020

Redox regulation of PTEN by S-nitrosothiols

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12 December 2020

Increased glutathionylated hemoglobin (HbSSG) in type 2 diabetes subjects with microangiopathy

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12 December 2020

Structural insights into Alzheimer filament assembly pathways based on site-directed mutagenesis and S-glutathionylation of three-repeat neuronal Tau protein

1 reference

12 December 2020

A novel thiol oxidation-based mechanism for adriamycin-induced cell injury in human macrophages

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12 December 2020

Cataracts: role of the unfolded protein response

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12 December 2020

Decline of contractility during ischemia-reperfusion injury: actin glutathionylation and its effect on allosteric interaction with tropomyosin

1 reference

12 December 2020

A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins

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12 December 2020

Proteomic analysis on multi-drug resistant cells HL-60/DOX of acute myeloblastic leukemia

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12 December 2020

The unfolded protein response: a novel component of the hypoxic stress response in tumors.

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12 December 2020

Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes

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12 December 2020

The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites

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12 December 2020

Absence of typical unfolded protein response in primary cultured cystic fibrosis airway epithelial cells

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12 December 2020

Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals

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12 December 2020

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

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12 December 2020

Protein disulfide isomerase serves as a molecular chaperone to maintain estrogen receptor alpha structure and function.

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12 December 2020

Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo

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12 December 2020

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

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12 December 2020

Redox regulation of beta-actin during integrin-mediated cell adhesion.

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12 December 2020

A transverse tubule NADPH oxidase activity stimulates calcium release from isolated triads via ryanodine receptor type 1 S -glutathionylation.

1 reference

12 December 2020

A novel role for human sulfiredoxin in the reversal of glutathionylation.

1 reference

12 December 2020

Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells

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12 December 2020

Prx1 suppresses radiation-induced c-Jun NH2-terminal kinase signaling in lung cancer cells through interaction with the glutathione S-transferase Pi/c-Jun NH2-terminal kinase complex.

1 reference

12 December 2020

Glutathionylation Induces the Dissociation of 1-Cys D-peroxiredoxin Non-covalent Homodimer

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12 December 2020

Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

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12 December 2020

Thioredoxin-1 and posttranslational modifications

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12 December 2020

Membrane skeletal protein S-glutathionylation and hemolysis in human red blood cells.

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12 December 2020

Glutaredoxin regulates nuclear factor kappa-B and intercellular adhesion molecule in Müller cells: model of diabetic retinopathy

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12 December 2020

Site-specific S-glutathiolation of mitochondrial NADH ubiquinone reductase

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12 December 2020

Modulation of Cellular Disulfide-Bond Formation and the ER Redox Environment by Feedback Regulation of Ero1

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12 December 2020

Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.

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12 December 2020

The functional role of cysteine residues for c-Abl kinase activity.

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12 December 2020

Gamma-glutamyltransferase, redox regulation and cancer drug resistance

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12 December 2020

Cysteine redox sensor in PKGIa enables oxidant-induced activation

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12 December 2020

Endoplasmic reticulum stress as a novel therapeutic target in heart diseases

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12 December 2020

NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance

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12 December 2020

Redox pathways in cancer drug discovery

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12 December 2020

Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene

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12 December 2020

Simultaneous characterizations of 3-prolylhydroxylase and 4-prolylhydroxylase activities by ion exchange chromatography

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12 December 2020

The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins

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12 December 2020

Glutathione-associated enzymes in anticancer drug resistance.

1 reference

12 December 2020

Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms

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12 December 2020

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

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12 December 2020

Nitric oxide in the vasculature: physiology and pathophysiology

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12 December 2020

Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver

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12 December 2020

Protein expression profiles in human breast ductal carcinoma and histologically normal tissue

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12 December 2020

Identifiers

DOI

10.1124/MI.7.6.7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199853%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18199853%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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