Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis. (Q37030035)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27445819%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis (English)

1 reference

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19 March 2020

1 reference

5

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19 March 2020

author name string

Hayley C Warsinske

1

1 reference

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19 March 2020

Amanda K Wheaton

2

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19 March 2020

Kevin K Kim

3

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19 March 2020

Jennifer J Linderman

4

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19 March 2020

Denise E Kirschner

6

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19 March 2020

publication date

23 June 2016

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Frontiers in Pharmacology

19 March 2020

published in

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19 March 2020

volume

7

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19 March 2020

page(s)

183

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Pharmacological treatment of idiopathic pulmonary fibrosis - preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine

19 March 2020

cites work

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4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Traveling wave model to interpret a wound-healing cell migration assay for human peritoneal mesothelial cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

A novel, non-prostanoid EP2 receptor-selective prostaglandin E2 agonist stimulates local bone formation and enhances fracture healing

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Potential Action of IL-4 and IL-13 as Fibrogenic Factors on Lung Fibroblasts in vitro

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Emerging patterns in tumor systems: simulating the dynamics of multicellular clusters with an agent-based spatial agglomeration model.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Alveolar epithelial cell inhibition of fibroblast proliferation is regulated by MCP-1/CCR2 and mediated by PGE2.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Consequences of altered TGF-beta expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Quality of life of idiopathic pulmonary fibrosis patients.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917547

IL-4, IL-13, and dexamethasone augment fibroblast proliferation in asthma

4 September 2018

1 reference

12 December 2020

IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase-dependent pathway

1 reference

12 December 2020

Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model

1 reference

12 December 2020

1 reference

12 December 2020

A critical function for TGF-beta signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

1 reference

12 December 2020

Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action

1 reference

12 December 2020

Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis

1 reference

12 December 2020

Therapeutic advances in idiopathic pulmonary fibrosis

1 reference

12 December 2020

The differential effect of prostaglandin E2 on transforming growth factor-beta and insulin-induced collagen formation in lung fibroblasts

1 reference

12 December 2020

The effect of transforming growth factor-beta on cell proliferation and collagen formation by lung fibroblasts

1 reference

12 December 2020

Drug-induced pulmonary fibrosis

1 reference

12 December 2020

Isolation and primary culture of murine alveolar type II cells

1 reference

12 December 2020

Transforming growth factor beta 1 functions in monocytic differentiation of hematopoietic cells through autocrine and paracrine mechanisms

1 reference

12 December 2020

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

1 reference

2 April 2022

https://opencitations.net/index/coci/api/v1/references/10.3389/FPHAR.2016.00183

Identifiers

DOI

10.3389/FPHAR.2016.00183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27445819%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27445819%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference