Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer (Q37022652)

17 August 2017

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title

Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer (English)

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17 August 2017

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Aparicio Gallego G

1

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17 August 2017

Díaz Prado S

2

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17 August 2017

Jiménez Fonseca P

3

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17 August 2017

García Campelo R

4

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17 August 2017

Cassinello Espinosa J

5

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17 August 2017

Antón Aparicio LM

6

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17 August 2017

1 November 2007

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Clinical and Translational Oncology

17 August 2017

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17 August 2017

9

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17 August 2017

11

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17 August 2017

694-702

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https://scigraph.springernature.com/pub.10.1007/s12094-007-0126-0

17 August 2017

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cites work

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

1 reference

https://api.crossref.org/works/10.1007%2FS12094-007-0126-0

Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-007-0126-0

Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-007-0126-0

Induction of cyclo-oxygenase-2 mRNA by prostaglandin E2 in human prostatic carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-007-0126-0

The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12094-007-0126-0

Arachidonic acid metabolism in benign and malignant prostatic tissue in vitro: effects of fatty acids and cyclooxygenase inhibitors

21 January 2018

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12 December 2020

Induction of prostaglandin G/H synthase-2 in a canine model of spontaneous prostatic adenocarcinoma

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12 December 2020

Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms

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12 December 2020

Cytoplasmic induction and over-expression of cyclooxygenase-2 in human prostate cancer: implications for prevention and treatment

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12 December 2020

Influence of acetylsalicylic acid and metabolites on DU-145 prostatic cancer cell proliferation

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12 December 2020

Prostaglandin E2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cells

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12 December 2020

Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma.

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12 December 2020

Role of arachidonic acid metabolism in the mitogenic response of BALB/c 3T3 fibroblasts to epidermal growth factor

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12 December 2020

Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines

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12 December 2020

Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer

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12 December 2020

AP-1--Introductory remarks

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12 December 2020

CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1

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12 December 2020

Aspirin use and chronic diseases: a cohort study of the elderly

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12 December 2020

Therapeutic implications of enhanced G(0)/G(1) checkpoint control induced by coculture of prostate cancer cells with osteoblasts

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12 December 2020

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

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12 December 2020

Cyclooxygenase-2: a target for the prevention and treatment of breast cancer

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12 December 2020

Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells

1 reference

12 December 2020

Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

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12 December 2020

Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I, and a protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines

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12 December 2020

NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells

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12 December 2020

Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer

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12 December 2020

Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: effects on cyclooxygenase-2, cell cycle regulation, and apoptosis mechanism(s).

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12 December 2020

Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines. Implications for cellular proliferation and differentiation

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12 December 2020

Sulindac inhibits activation of the NF-kappaB pathway

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12 December 2020

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

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12 December 2020

Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma

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12 December 2020

Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention

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12 December 2020

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

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12 December 2020

Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism

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12 December 2020

Role of plasmalemmal caveolae in signal transduction.

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12 December 2020

Expression of cyclooxygenase-2 in prostate carcinoma.

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12 December 2020

Taxol and estramustine-induced modulation of human prostate cancer cell apoptosis via alteration in bcl-xL and bak expression

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12 December 2020

Effects of Ca++ mobilization on expression of androgen-regulated genes: interference with androgen receptor-mediated transactivation by AP-I proteins

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12 December 2020

Adenocarcina of the mouse prostate growth inhibition by celecoxib: downregulation of transcription factors involved in COX-2 inhibition

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12 December 2020

Cholesterol-rich lipid rafts mediate akt-regulated survival in prostate cancer cells

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12 December 2020

New advances on prostate carcinogenesis and therapies: involvement of EGF-EGFR transduction system

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12 December 2020

Safety and efficacy of exisulind for treatment of recurrent prostate cancer after radical prostatectomy

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12 December 2020

12-lipoxygenases and 12(S)-HETE: role in cancer metastasis

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12 December 2020

Expression of cyclooxygenase-1 and cyclooxygenase-2 in the human prostate

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12 December 2020

Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP

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12 December 2020

Lessons from hereditary colorectal cancer

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12 December 2020

Immunohistochemical study of cyclooxygenases in prostatic adenocarcinoma; relationship to apoptosis and Bcl-2 protein expression

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12 December 2020

Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma

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12 December 2020

Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

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12 December 2020

EGF receptor signaling in prostate morphogenesis and tumorigenesis

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12 December 2020

Docosahexaenoic acid in combination with celecoxib modulates HSP70 and p53 proteins in prostate cancer cells

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12 December 2020

HER-2 profiling and targeting in prostate carcinoma

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12 December 2020

Interaction between epidermal growth factor receptor- and cyclooxygenase 2-mediated pathways and its implications for the chemoprevention of head and neck cancer

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12 December 2020

3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells

1 reference

12 December 2020

Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth

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12 December 2020

Weekly administration of docetaxel in combination with estramustine and celecoxib in patients with advanced hormone-refractory prostate cancer: final results from a phase II study

1 reference

12 December 2020

Aspirin use and risk of fatal cancer

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12 December 2020

Inhibition of cyclooxygenase-2 suppresses angiogenesis and the growth of prostate cancer in vivo

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12 December 2020

Expression, subcellular localization and putative function of platelet-type 12-lipoxygenase in human prostate cancer cell lines of different metastatic potential

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12 December 2020

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

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12 December 2020

Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells.

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12 December 2020

Role of the tumor microenvironment in mediating de novo resistance to drugs and physiological mediators of cell death

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12 December 2020

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers

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12 December 2020

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

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12 December 2020

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

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12 December 2020

Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells

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12 December 2020

The cyclooxygenase 2-specific nonsteroidal anti-inflammatory drugs celecoxib and nimesulide inhibit androgen receptor activity via induction of c-Jun in prostate cancer cells.

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12 December 2020

Synergistic antiproliferative and apoptotic effects induced by mixed epidermal growth factor receptor inhibitor ZD1839 and nitric oxide donor in human prostatic cancer cell lines

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12 December 2020

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

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12 December 2020

Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate.

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12 December 2020

Effects of fatty acids and eicosanoid synthesis inhibitors on the growth of two human prostate cancer cell lines

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12 December 2020

Apoptosis signaling pathways mediated by cyclooxygenase-2 inhibitors in prostate cancer cells

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12 December 2020

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

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12 December 2020

10.1007/S12094-007-0126-0

Identifiers

DOI

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17 August 2017

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