TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation. (Q37019308)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18598698%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation (English)

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10 January 2020

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1

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10 January 2020

8

Stephan R Targan

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10 January 2020

author name string

Kathrin S Michelsen

2

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10 January 2020

Bo Wei

3

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10 January 2020

Carol J Landers

4

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10 January 2020

Lisa S Thomas

5

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10 January 2020

Deepti Dhall

6

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10 January 2020

Jonathan Braun

7

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10 January 2020

language of work or name

English

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publication date

7 May 2008

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10 January 2020

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10 January 2020

volume

135

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10 January 2020

issue

2

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10 January 2020

page(s)

552-567

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Microbial influences in inflammatory bowel diseases

10 January 2020

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1 reference

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TNFSF15 is an ethnic-specific IBD gene

29 September 2017

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Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

29 September 2017

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Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis

29 September 2017

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The T cell costimulator TL1A is induced by FcgammaR signaling in human monocytes and dendritic cells

29 September 2017

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Role of TL1A and its receptor DR3 in two models of chronic murine ileitis

29 September 2017

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IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

29 September 2017

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

29 September 2017

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Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease

29 September 2017

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

29 September 2017

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Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

29 September 2017

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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

29 September 2017

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Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota

29 September 2017

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Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets

29 September 2017

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

29 September 2017

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Anti-interleukin-12 antibody for active Crohn's disease

29 September 2017

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Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-gamma, in mucosal inflammation

29 September 2017

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Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease

29 September 2017

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The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut

29 September 2017

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TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator

29 September 2017

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29 September 2017

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T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells

29 September 2017

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29 September 2017

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Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice.

29 September 2017

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Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice

29 September 2017

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Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines

27 June 2018

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27 June 2018

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Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

4 September 2018

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Dominant role for TL1A/DR3 pathway in IL-12 plus IL-18-induced IFN-gamma production by peripheral blood and mucosal CCR9+ T lymphocytes

4 September 2018

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4 September 2018

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4 September 2018

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4 September 2018

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Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

4 December 2018

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12 December 2020

Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis

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12 December 2020

IL-6 is required for the development of Th1 cell-mediated murine colitis

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12 December 2020

G(alpha)i2-deficient mice with colitis exhibit a local increase in memory CD4+ T cells and proinflammatory Th1-type cytokines

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12 December 2020

Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients

1 reference

12 December 2020

10.1053/J.GASTRO.2008.04.037

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18598698%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18598698%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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