Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma (Q37003332)

17 August 2017

Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma (English)

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17 August 2017

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J Shen

1

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17 August 2017

H Zheng

2

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17 August 2017

J Ruan

3

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17 August 2017

W Fang

4

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17 August 2017

A Li

5

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G Tian

6

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X Niu

7

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S Luo

8

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17 August 2017

P Zhao

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17 August 2017

language of work or name

English

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publication date

25 June 2013

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British Journal of Cancer

17 August 2017

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17 August 2017

109

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17 August 2017

164-171

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17 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/bjc.2013.306

17 August 2017

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29 September 2017

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Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells

29 September 2017

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Deconvoluting the context-dependent role for autophagy in cancer

29 September 2017

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Hypoxia-induced autophagy promotes tumor cell survival and adaptation to antiangiogenic treatment in glioblastoma

29 September 2017

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V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis

29 September 2017

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Vandetanib for the treatment of thyroid cancer

29 September 2017

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Recurrent glioblastoma: a fresh look at current therapies and emerging novel approaches

29 September 2017

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29 September 2017

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Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

29 September 2017

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EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells

29 September 2017

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Principles and current strategies for targeting autophagy for cancer treatment

29 September 2017

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Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma

29 September 2017

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The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex

29 September 2017

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ZD6474, a multitargeted inhibitor for receptor tyrosine kinases, suppresses growth of gliomas expressing an epidermal growth factor receptor mutant, EGFRvIII, in the brain

29 September 2017

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Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma

29 September 2017

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Autophagy suppresses tumorigenesis through elimination of p62

29 September 2017

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Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

29 September 2017

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Bcl-2 family members: dual regulators of apoptosis and autophagy

29 September 2017

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Inhibition of N-(4-hydroxyphenyl)retinamide-induced autophagy at a lower dose enhances cell death in malignant glioma cells

29 September 2017

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

29 September 2017

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Induction of cell cycle arrest and apoptosis in human nasopharyngeal carcinoma cells by ZD6474, an inhibitor of VEGFR tyrosine kinase with additional activity against EGFR tyrosine kinase.

29 September 2017

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Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial

29 September 2017

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ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors

29 September 2017

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Autophagy in health and disease: a double-edged sword

29 September 2017

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The impact of sequential vs. combined radiochemotherapy with temozolomide, resection and MGMT promoter hypermethylation on survival of patients with primary glioblastoma--a single centre retrospective study.

29 September 2017

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Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence.

4 September 2018

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Vandetanib in locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 2 trial.

4 September 2018

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Neurosurgical management and prognosis of patients with glioblastoma that progresses during bevacizumab treatment.

4 September 2018

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Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity.

4 September 2018

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Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models.

4 September 2018

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Potent antitumor effects of ZD6474 on neuroblastoma via dual targeting of tumor cells and tumor endothelium.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3708568

ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3708568

ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FBJC.2013.306

Vandetanib Versus placebo in patients with advanced non-small-cell lung cancer after prior therapy with an epidermal growth factor receptor tyrosine kinase inhibitor: a randomized, double-blind phase III trial (ZEPHYR)

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23799852

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BJC.2013.306

1 reference

Dimensions Publication ID

17 August 2017

0 references

1 reference

17 August 2017

1 reference