Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses (Q36989992)

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scientific article published on May 2012

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English	Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses	scientific article published on May 2012

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scholarly article

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27 January 2020

Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses (English)

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27 January 2020

William H. Kitchens

1

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27 January 2020

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Divya Haridas

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27 January 2020

Maylene E Wagener

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27 January 2020

Mingqing Song

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27 January 2020

Mandy L Ford

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27 January 2020

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1 May 2012

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27 January 2020

Transplantation

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27 January 2020

93

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27 January 2020

997-1005

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27 January 2020

10

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27 January 2020

LFA-1 blockade induces effector and regulatory T-cell enrichment in lymph nodes and synergizes with CTLA-4Ig to inhibit effector function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates

1 reference

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9 September 2017

Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

LFA-1-specific therapy prolongs allograft survival in rhesus macaques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Integrins as therapeutic targets: lessons and opportunities

1 reference

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9 September 2017

Essential roles of VLA-4 in the hematopoietic system

1 reference

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9 September 2017

Natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: lessons from 28 cases

1 reference

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9 September 2017

Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project

1 reference

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9 September 2017

Leukocyte-endothelial interactions in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Integrins in immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Costimulation blockade: towards clinical application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Integrin modulation and signaling in leukocyte adhesion and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Transplant tolerance through costimulation blockade--are we there yet?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

The impact of memory T cells on rejection and the induction of tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

A new look at blockade of T-cell costimulation: a therapeutic strategy for long-term maintenance immunosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Therapeutic anti-integrin (alpha4 and alphaL) monoclonal antibodies: two-edged swords?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

The bone marrow: a nest for migratory memory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Integrins and T cell-mediated immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Heterologous immunity provides a potent barrier to transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

The immunological synapse: integrins take the stage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

9 September 2017

Allo-HLA reactivity of virus-specific memory T cells is common

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

29 September 2017

Anti-CD40 monoclonal antibody synergizes with CTLA4-Ig in promoting long-term graft survival in murine models of transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

29 September 2017

Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

29 September 2017

Integrin antagonists for transplant immunosuppression: panacea or peril?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

27 June 2018

Progressive multifocal leukoencephalopathy: can we reduce risk in patients receiving biological immunomodulatory therapies?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Stronger association of drug-induced progressive multifocal leukoencephalopathy (PML) with biological immunomodulating agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Pretransplant cellular alloimmunity as assessed by a panel of reactive T cells assay correlates with acute renal graft rejection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Perturbation of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 results in differential outcomes in cardiac vs islet allograft survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

The effect of simultaneous CD154 and LFA-1 blockade on the survival of allogeneic islet grafts in nonobese diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: therapeutic implications for sensitized transplant recipients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

alpha4 integrin in islet allograft rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 September 2018

CTLA4ig induces long-term graft survival of allogeneic skin grafts and totally inhibits T-cell proliferation in LFA-1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

20 October 2018

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

20 October 2018

TCR affinity and negative regulation limit autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703766

4 December 2018

Acceptance of primary skin graft after treatment with anti-intercellular adhesion molecule-1 and anti-leukocyte function-associated antigen-1 monoclonal antibodies in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of anti-intercellular adhesion molecule-1 and anti-leukocyte function associated antigen-1 monoclonal antibodies on rat-to-mouse cardiac xenograft rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Awareness of donor alloantigens in antiadhesion therapy induces antigen-specific unresponsiveness to islet allografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting LFA-1 Synergizes with CD40/CD40L Blockade for Suppression of Both CD4-Dependent and CD8-Dependent Rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The efficacy of LFA-1 and VLA-4 antibody treatment in rat vascularized cardiac allograft rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppression to cardiac allografts and soluble antigens by anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation of islet allograft survival with an antibody to vascular cell adhesion molecule 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preventing effect of anti-ICAM-1 and anti-LFA-1 monoclonal antibodies on murine islet allograft rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase III study of belatacept versus cyclosporine in kidney transplants from extended criteria donors (BENEFIT-EXT study)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22475765

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/TP.0B013E31824E75D7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22475765%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22475765%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22475765%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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