The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals (Q36986235)

17 August 2017

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals (English)

1 reference

17 August 2017

Lisa C Watson

1

1 reference

17 August 2017

Kristopher M Kuchenbecker

2

1 reference

17 August 2017

Benjamin J Schiller

3

1 reference

17 August 2017

John D Gross

4

1 reference

17 August 2017

Miles A Pufall

5

1 reference

17 August 2017

Keith R Yamamoto

6

1 reference

17 August 2017

2 June 2013

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Nature Structural & Molecular Biology

17 August 2017

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17 August 2017

20

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17 August 2017

876-883

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17 August 2017

7

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describes a project that uses

17 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3702670/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nsmb.2595

0 references

cites work

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Glucocorticoid receptor-promoter interactions: energetic dissection suggests a framework for the specificity of steroid receptor-mediated gene regulation

29 September 2017

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29 September 2017

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Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.

29 September 2017

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Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators

29 September 2017

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The glucocorticoid receptor and the coregulator Brm selectively modulate each other's occupancy and activity in a gene-specific manner

29 September 2017

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29 September 2017

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Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

29 September 2017

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DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex

29 September 2017

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Mapping allostery through the covariance analysis of NMR chemical shifts

29 September 2017

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Ligand binding domain mutations of the glucocorticoid receptor selectively modify the effects with, but not binding of, cofactors

29 September 2017

1 reference

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Molecular switch in the glucocorticoid receptor: active and passive antagonist conformations

29 September 2017

1 reference

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The role of DNA shape in protein-DNA recognition

29 September 2017

1 reference

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Site-specific phosphorylation induces functionally active conformation in the intrinsically disordered N-terminal activation function (AF1) domain of the glucocorticoid receptor

29 September 2017

1 reference

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Conformational analysis of nucleic acids revisited: Curves+

29 September 2017

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DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

29 September 2017

1 reference

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Mutations of glucocorticoid receptor differentially affect AF2 domain activity in a steroid-selective manner to alter the potency and efficacy of gene induction and repression

29 September 2017

1 reference

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Allosteric cooperativity in protein kinase A.

29 September 2017

1 reference

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Functional Specificity of a Hox Protein Mediated by the Recognition of Minor Groove Structure

29 September 2017

1 reference

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Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor

29 September 2017

1 reference

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A conformational switch in the ligand-binding domain regulates the dependence of the glucocorticoid receptor on Hsp90.

29 September 2017

1 reference

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Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

29 September 2017

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Conformational changes of the glucocorticoid receptor ligand binding domain induced by ligand and cofactor binding, and the location of cofactor binding sites determined by hydrogen/deuterium exchange mass spectrometry

29 September 2017

1 reference

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Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity

29 September 2017

1 reference

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Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

29 September 2017

1 reference

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Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor

29 September 2017

1 reference

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The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism

29 September 2017

1 reference

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Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

29 September 2017

1 reference

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Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements.

29 September 2017

1 reference

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Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification

29 September 2017

1 reference

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Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

29 September 2017

1 reference

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The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

29 September 2017

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Building transcriptional regulatory complexes: signals and surfaces

29 September 2017

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

29 September 2017

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TROSY in triple-resonance experiments: new perspectives for sequential NMR assignment of large proteins

29 September 2017

1 reference

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Structure and specificity of nuclear receptor-coactivator interactions

29 September 2017

1 reference

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Molecular basis of agonism and antagonism in the oestrogen receptor

29 September 2017

1 reference

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Three amino acid substitutions selectively disrupt the activation but not the repression function of the glucocorticoid receptor N terminus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Refined solution structure of the glucocorticoid receptor DNA-binding domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Analysis of the DNA-binding affinity, sequence specificity and context dependence of the glucocorticoid receptor zinc finger region

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

A heteronuclear correlation experiment for simultaneous determination of 15N longitudinal decay and chemical exchange rates of systems in slow equilibrium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Quantitative model for gene regulation by lambda phage repressor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Solution structure of the glucocorticoid receptor DNA-binding domain

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Glucocorticoid receptor-DNA interactions: binding energetics are the primary determinant of sequence-specific transcriptional activity

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Structural determinants of allosteric ligand activation in RXR heterodimers.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

DNA-induced conformational changes are the basis for cooperative dimerization by the DNA binding domain of the retinoid X receptor.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3). Species-specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphoryl

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Allosteric effects of DNA on transcriptional regulators

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702670

Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2595

TROSY-type Triple-Resonance Experiments for Sequential NMR Assignments of Large Proteins

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2595

An optimized 3D NOESY-HSQC

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2595

31 March 2020

Identifiers

DOI

10.1038/NSMB.2595

1 reference

Dimensions Publication ID

17 August 2017

1003005609

0 references

Fatcat ID

release_y5m7ee2vanbmzkutrde6262ooe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/y5m7ee2vanbmzkutrde6262ooe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

17 August 2017

1 reference