Electroporation-based DNA immunisation: translation to the clinic (Q36981658)

17 August 2017

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title

Electroporation-based DNA immunisation: translation to the clinic (English)

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17 August 2017

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Alain Luxembourg

1

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17 August 2017

Claire F Evans

series ordinal

2

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17 August 2017

Drew Hannaman

series ordinal

3

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17 August 2017

language of work or name

English

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publication date

1 November 2007

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Expert Opinion on Biological Therapy

17 August 2017

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17 August 2017

7

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17 August 2017

1647-1664

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17 August 2017

11

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Genetic immunization is a simple method for eliciting an immune response

17 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Heterologous protection against influenza by injection of DNA encoding a viral protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Gene inoculation generates immune responses against human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

DNA vaccines: immunology, application, and optimization*

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

DNA vaccines--back in the saddle again?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Immunization of livestock with DNA vaccines: current studies and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Microparticles for the delivery of DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Rational design of gene-based vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

ZYC101a for treatment of high-grade cervical intraepithelial neoplasia: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Gene-based vaccines: recent technical and clinical advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vitro simian virus 40 large tumor antigen expression correlates with differential immune responses following DNA immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vivo gene introduction into keratinocytes using jet injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Evidence for antigen production in muscles by dengue and Japanese encephalitis DNA vaccines and a relation to their immunogenicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Comparison of DNA application methods to reduce BRSV shedding in cattle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Comparative evaluation of three different intramuscular delivery methods for DNA immunization in a nonhuman primate animal model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Safety, tolerability, and lack of antibody responses after administration of a PfCSP DNA malaria vaccine via needle or needle-free jet injection, and comparison of intramuscular and combination intramuscular/intradermal routes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 DNA candidate vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Safety and immunogenicity of a Gag-Pol candidate HIV-1 DNA vaccine administered by a needle-free device in HIV-1-seronegative subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Biological features of genetic immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Particle-mediated DNA vaccine delivery to the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Effects of high electric fields on micro-organisms. 3. Lysis of erythrocytes and protoplasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electrical Breakdown of Bimolecular Lipid Membranes as an Electromechanical Instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electrical hemolysis of human and bovine red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Hemolysis of human erythrocytes by transient electric field

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Formation and resealing of pores of controlled sizes in human erythrocyte membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electroporation in biology: methods, applications, and instrumentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electroporation of cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Transient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Optimal Electric Conditions in Electrical Impulse Chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Bleomycin-mediated electrochemotherapy of basal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vivo electroporation and stable transformation of skin cells of newborn mice by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Theory and in vivo application of electroporative gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electric pulse-mediated gene delivery to various animal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Gene transfer into muscle by electroporation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Long-term, high level in vivo gene expression after electric pulse-mediated gene transfer into skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Efficient nonviral cutaneous transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Cutaneous transfection and immune responses to intradermal nucleic acid vaccination are significantly enhanced by in vivo electropermeabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Increased DNA vaccine delivery and immunogenicity by electroporation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Protection against influenza virus infection in mice immunized by administration of hemagglutinin-expressing DNAs with electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Cross-protection against a lethal influenza virus infection by DNA vaccine to neuraminidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electroporated DNA vaccine clears away multifocal mammary carcinomas in her-2/neu transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Anti-HER-2 DNA vaccine protects Syrian hamsters against squamous cell carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Enhancement of cellular immune response to a prostate cancer DNA vaccine by intradermal electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Smallpox DNA vaccine delivered by novel skin electroporation device protects mice against intranasal poxvirus challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Enhancement of immune responses to an HBV DNA vaccine by electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Modulation of the immune response induced by gene electrotransfer of a hepatitis C virus DNA vaccine in nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Enhancement of DNA vaccine potency in rhesus macaques by electroporation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

A single DNA immunization in combination with electroporation prolongs the primary immune response and maintains immune memory for six months

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

DNA injection in combination with electroporation: a novel method for vaccination of farmed ruminants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Co-delivery of plasmid-encoded cytokines modulates the immune response to a DNA vaccine delivered by in vivo electroporation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Increased gene expression and inflammatory cell infiltration caused by electroporation are both important for improving the efficacy of DNA vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Skin electroporation for transdermal and topical delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electropermeabilization of skeletal muscle enhances gene transfer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

The importance of electric field distribution for effective in vivo electroporation of tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electrochemotherapy--a novel method of cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vivo electroporation of skeletal muscle: threshold, efficacy and relation to electric field distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electroporation and electrophoretic DNA transfer into cells. The effect of DNA interaction with electropores

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Fundamentals of electroporative delivery of drugs and genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electrophoretic component of electric pulses determines the efficacy of in vivo DNA electrotransfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vivo DNA gene electro-transfer: a systematic analysis of different electrical parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Myogenic expression of an injectable protease-resistant growth hormone-releasing hormone augments long-term growth in pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Gene expression and immune response kinetics using electroporation-mediated DNA delivery to muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Skin-targeted gene transfer using in vivo electroporation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vivo assessment of skin electroporation using square wave pulses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Optimization of cutaneous electrically mediated plasmid DNA delivery using novel electrode

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Factors affecting the decision of nursing students in Taiwan to be vaccinated against hepatitis B infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electrochemotherapy: results of cancer treatment using enhanced delivery of bleomycin by electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

A novel electroporation device for gene delivery in large animals and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Preclinical and clinical safety studies on DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: plasmid dependence of muscle damage and effect of poloxamer 188.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Optimizing plasmid-based gene transfer for investigating skeletal muscle structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

FVIII gene delivery by muscle electroporation corrects murine hemophilia A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vivo efficacy and safety of skin electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Gene transfer vector biodistribution: pivotal safety studies in clinical gene therapy development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Biodistribution of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar, without Integration, despite Differing Plasmid Backbones or Gene Inserts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Plasmid DNA malaria vaccine: the potential for genomic integration after intramuscular injection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

I. Poloxamer-formulated plasmid DNA-based human cytomegalovirus vaccine: evaluation of plasmid DNA biodistribution/persistence and integration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

II. Cationic lipid-formulated plasmid DNA-based Bacillus anthracis vaccine: evaluation of plasmid DNA persistence and integration potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Potential DNA vaccine integration into host cell genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Protection against anthrax lethal toxin challenge by genetic immunization with a plasmid encoding the lethal factor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

The immunodominant, Ld-restricted T cell response to hepatitis B surface antigen (HBsAg) efficiently suppresses T cell priming to multiple Dd-, Kd-, and Kb-restricted HBsAg epitopes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

Review of the use of statistics in infection and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

In vivo gene electroinjection and expression in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.11.1647

10.1517/14712598.7.11.1647

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference