Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia (Q36973664)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23733784%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia (English)

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2 March 2020

1 reference

Gabriela Gonzalez-Perez

2

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2 March 2020

Lucio Miele

10

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2 March 2020

author name string

Justine E Roderick

1

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2 March 2020

Christina Arieta Kuksin

3

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2 March 2020

Anushka Dongre

4

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2 March 2020

Emily R Roberts

5

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2 March 2020

Janani Srinivasan

6

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2 March 2020

Chester Andrzejewski

7

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2 March 2020

Abdul H Fauq

8

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2 March 2020

Todd E Golde

9

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2 March 2020

Lisa M Minter

11

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2 March 2020

language of work or name

English

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publication date

3 June 2013

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Journal of Experimental Medicine

2 March 2020

published in

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2 March 2020

volume

210

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2 March 2020

issue

7

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2 March 2020

page(s)

1311-1329

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Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells.

2 March 2020

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Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin

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The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

29 September 2017

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Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura

29 September 2017

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Hedgehog signaling is dispensable for adult hematopoietic stem cell function

29 September 2017

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Myelodysplasia and acute leukemia as late complications of marrow failure: future prospects for leukemia prevention.

29 September 2017

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Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

29 September 2017

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Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

29 September 2017

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CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS

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29 September 2017

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29 September 2017

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29 September 2017

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T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

29 September 2017

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JLK isocoumarin inhibitors: selective gamma-secretase inhibitors that do not interfere with notch pathway in vitro or in vivo

29 September 2017

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New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage

29 September 2017

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Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

29 September 2017

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A novel transcription factor, T-bet, directs Th1 lineage commitment

29 September 2017

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29 September 2017

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Correlating notch signaling with thymocyte maturation

29 September 2017

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The polymorphisms of T cell-specific TBX21 and STAT4 genes may contribute to the susceptibility of Chinese individuals to aplastic anemia.

29 September 2017

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Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia

4 September 2018

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Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells

4 September 2018

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Targeting Notch signaling in autoimmune and lymphoproliferative disease

4 September 2018

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Mutations of the Notch1 gene in T-cell acute lymphoblastic leukemia: analysis in adults and children.

4 September 2018

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Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells

4 September 2018

1 reference

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TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells

4 September 2018

1 reference

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Notch signaling augments T cell responsiveness by enhancing CD25 expression

4 September 2018

1 reference

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Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasia

4 September 2018

1 reference

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The nervous system and innate immunity: the neuropeptide connection

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20112615

Itch genetically interacts with Notch1 in a mouse autoimmune disease model

21 January 2018

1 reference

12 December 2020

Minor antigen h60-mediated aplastic anemia is ameliorated by immunosuppression and the infusion of regulatory T cells

1 reference

12 December 2020

1 reference

12 December 2020

A mouse model of lymphocyte infusion-induced bone marrow failure

1 reference

12 December 2020

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

1 reference

12 December 2020

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20112615

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23733784%20AND%20SRC:MED&resulttype=core&format=json

release_2e5mt4rk3bdptgaf67ezkm4jna

2 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/2e5mt4rk3bdptgaf67ezkm4jna

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23733784%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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