Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase (Q36932565)

17 August 2017

Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase (English)

1 reference

17 August 2017

1

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5 June 2020

author name string

Wayne K W Chou

2

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5 June 2020

Naeemah Al-Lami

3

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5 June 2020

Juan A Faraldos

4

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5 June 2020

Rudolf K Allemann

5

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5 June 2020

David E Cane

6

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5 June 2020

David W Christianson

7

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5 June 2020

language of work or name

English

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publication date

12 May 2016

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17 August 2017

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5 June 2020

volume

55

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5 June 2020

issue

20

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5 June 2020

page(s)

2864-2874

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Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi -Isozizaene Synthase

5 June 2020

cites work

1 reference

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Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism

29 September 2017

1 reference

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Mechanistic Insights from the Binding of Substrate and Carbocation Intermediate Analogues to Aristolochene Synthase

29 September 2017

1 reference

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Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C -Methylated Monoterpenoid Substrate

29 September 2017

1 reference

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Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

29 September 2017

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29 September 2017

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29 September 2017

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Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor

29 September 2017

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The function of terpene natural products in the natural world

29 September 2017

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Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function

29 September 2017

1 reference

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Structural biology and chemistry of the terpenoid cyclases

29 September 2017

1 reference

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Coot: model-building tools for molecular graphics

29 September 2017

1 reference

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Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879067

Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase

29 September 2017

1 reference

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X-ray crystal structures of D100E trichodiene synthase and its pyrophosphate complex reveal the basis for terpene product diversity

29 September 2017

1 reference

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Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879067

Aristolochene synthase: purification, molecular cloning, high-level expression in Escherichia coli, and characterization of the Aspergillus terreus cyclase

29 September 2017

1 reference

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Genetic engineering of essential oil production in mint

29 September 2017

1 reference

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Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879067

Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase

29 September 2017

1 reference

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Structure and function of a squalene cyclase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879067

Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879067

Isoprenyl diphosphate synthases: protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure

29 September 2017

1 reference

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Trinuclear Metal Clusters in Catalysis by Terpenoid Synthases

29 September 2017

1 reference

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Isoprenoid biosynthesis: manifold chemistry catalyzed by similar enzymes

27 June 2018

1 reference

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Conformational change and ligand binding in the aristolochene synthase catalytic cycle

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879067

Synthesis of highly strained terpenes by non-stop tail-to-head polycyclization

4 September 2018

1 reference

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Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti

4 September 2018

1 reference

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Aristolochene synthase: mechanistic analysis of active site residues by site-directed mutagenesis

4 September 2018

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Identification of the single amino acid involved in quenching the ent-kauranyl cation by a water molecule in ent-kaurene synthase of Physcomitrella patens

4 September 2018

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12 December 2020

Genome Mining Reveals Two Novel Bacterial Sesquiterpene Cyclases: (−)-Germacradien-4-ol and (−)-epi-α-Bisabolol Synthases from Streptomyces citricolor

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Non enzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations

1 reference

12 December 2020

10.1021/ACS.BIOCHEM.6B00343

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DOI

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5 June 2020

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5 June 2020

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