Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design. (Q36922123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17996741%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

review article

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title

Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design (English)

1 reference

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10 January 2020

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4

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10 January 2020

author name string

Susan S Taylor

1

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10 January 2020

Choel Kim

2

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10 January 2020

Cecilia Y Cheng

3

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10 January 2020

Jian Wu

5

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10 January 2020

Natarajan Kannan

6

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10 January 2020

language of work or name

English

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publication date

12 October 2007

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Biochimica et Biophysica Acta

10 January 2020

published in

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10 January 2020

volume

1784

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10 January 2020

issue

1

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10 January 2020

page(s)

16-26

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PKA Type II Holoenzyme Reveals a Combinatorial Strategy for Isoform Diversity

10 January 2020

cites work

1 reference

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PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation

29 September 2017

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The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module

29 September 2017

1 reference

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cAMP activation of PKA defines an ancient signaling mechanism.

29 September 2017

1 reference

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A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase

29 September 2017

1 reference

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Compartmentation of cyclic nucleotide signaling in the heart: the role of A-kinase anchoring proteins

29 September 2017

1 reference

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PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking

29 September 2017

1 reference

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Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA

29 September 2017

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A-kinase-interacting protein localizes protein kinase A in the nucleus

29 September 2017

1 reference

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The cAMP binding domain: an ancient signaling module

29 September 2017

1 reference

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Regulation of protein kinases; controlling activity through activation segment conformation

29 September 2017

1 reference

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Identification of the protein kinase A regulatory R I α-catalytic subunit interface by amide H/ 2 H exchange and protein docking

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Designing isoform-specific peptide disruptors of protein kinase A localization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure

29 September 2017

1 reference

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Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Intracellular distribution of mammalian protein kinase A catalytic subunit altered by conserved Asn2 deamidation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Mobilization of the A-kinase N-myristate through an isoform-specific intermolecular switch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Dissecting cAMP binding domain A in the RIalpha subunit of cAMP-dependent protein kinase. Distinct subsites for recognition of cAMP and the catalytic subunit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Active and inactive protein kinases: structural basis for regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2561045

Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase

29 September 2017

1 reference

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

29 September 2017

1 reference

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Specificity in the cAMP/PKA signaling pathway. differential expression, regulation, and subcellular localization of subunits of PKA.

29 September 2017

1 reference

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Cyclic-AMP and pseudosubstrate effects on type-I A-kinase regulatory and catalytic subunit binding kinetics.

27 June 2018

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A model for agonism and antagonism in an ancient and ubiquitous cAMP-binding domain.

4 September 2018

1 reference

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Endogenous tryptophan residues of cAPK regulatory subunit type IIbeta reveal local variations in environments and dynamics

4 September 2018

1 reference

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Induction of flexibility through protein-protein interactions

4 September 2018

1 reference

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Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinase

4 September 2018

1 reference

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An adenosine 3',5'-monophosphate-dependant protein kinase from rabbit skeletal muscle

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17996741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular basis of AKAP specificity for PKA regulatory subunits

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17996741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIalpha

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17996741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BBAPAP.2007.10.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17996741%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17996741%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference