Targeting polyamine metabolism: a viable therapeutic/preventative solution for cancer? (Q36916921)

17 August 2017

1 reference

title

Targeting polyamine metabolism: a viable therapeutic/preventative solution for cancer? (English)

1 reference

17 August 2017

Heather M Wallace

1

1 reference

PubMed ID

17714063

17 August 2017

language of work or name

English

0 references

publication date

1 September 2007

1 reference

Expert Opinion on Pharmacotherapy

17 August 2017

1 reference

17 August 2017

8

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17 August 2017

13

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17 August 2017

2109-2116

1 reference

A perspective of polyamine metabolism

17 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Polyamines as targets for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Genetic approaches to the cellular functions of polyamines in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Molecular mechanisms of polyamine analogs in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Polyamine analogues as anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Properties of purified recombinant human polyamine oxidase, PAOh1/SMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Biochemical and growth-modulatory effects of the new S-adenosylmethionine decarboxylase inhibitor CGP 48664 in malignant and immortalized normal human breast epithelial cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Terminally alkylated polyamine analogues as chemotherapeutic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Cytotoxicity of novel unsymmetrically substituted inhibitors of polyamine biosynthesis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Long-chain polyamines (oligoamines) exhibit strong cytotoxicities against human prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Functional consequences of polyamine synthesis inhibition by L-alpha-difluoromethylornithine (DFMO): cellular mechanisms for DFMO-mediated ototoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Alpha-difluoromethylornithine and polyamine levels in the human prostate: results of a phase IIa trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Randomized prospective phase III trial of difluoromethylornithine vs placebo in preventing recurrence of completely resected low risk superficial bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Polyamines and neoplastic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Phase 1 study of N1-N11-diethylnorspermine (DENSPM) administered TID for 6 days in patients with advanced malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Phase I trial of the polyamine analog N1,N14-diethylhomospermine (DEHSPM) in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Clinical efficacy, tolerability, and safety of SAM486A, a novel polyamine biosynthesis inhibitor, in patients with relapsed or refractory non-Hodgkin's lymphoma: results from a phase II multicenter study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Polyamine-reduced diet in metastatic hormone-refractory prostate cancer (HRPC) patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.13.2109

10.1517/14656566.8.13.2109

21 January 2018

Identifiers

DOI

1 reference

release_nvqtautjlre2dngrskfuw7uu3a

17 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nvqtautjlre2dngrskfuw7uu3a

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24 November 2022

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PubMed ID

17714063

1 reference

PubMed ID

17714063