ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells (Q36916479)

17 August 2017

ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells (English)

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17 August 2017

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M Zulfiquer Hossain

1

1 reference

17 August 2017

Qing Yu

series ordinal

2

1 reference

17 August 2017

Mai Xu

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3

1 reference

17 August 2017

Jyoti Misra Sen

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4

1 reference

17 August 2017

28 May 2008

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17 August 2017

International Immunology

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17 August 2017

20

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17 August 2017

7

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17 August 2017

925-935

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Beta-catenin expression enhances IL-7 receptor signaling in thymocytes during positive selection

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Beta-catenin regulates positive selection of thymocytes but not lineage commitment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Key factors in the organized chaos of early T cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

The why and how of thymocyte negative selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

TCR and Notch signaling in CD4 and CD8 T-cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

At the crossroads: diverse roles of early thymocyte transcriptional regulators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Loss of adenomatous polyposis coli gene function disrupts thymic development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Beta-catenin is dispensable for hematopoiesis and lymphopoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Role for ICAT in β-catenin-dependent nuclear signaling and cadherin functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Deletion of β-catenin impairs T cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Disruption of thymocyte development and lymphomagenesis induced by SV40 T-antigen

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

ICAT is a multipotent inhibitor of beta-catenin. Focus on "role for ICAT in beta-catenin-dependent nuclear signaling and cadherin functions".

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

beta-Catenin expression enhances generation of mature thymocytes

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Beta-catenin expression in thymocytes accelerates thymic involution.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Wnt-1 and Wnt-4 regulate thymic cellularity.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection, TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2556852

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

4 September 2018

1 reference

12 December 2020

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin

1 reference

12 December 2020

Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis

1 reference

12 December 2020

An HMG-box-containing T-cell factor required for thymocyte differentiation.

1 reference

12 December 2020

CD28 costimulation prevents cell death during primary T cell activation

1 reference

12 December 2020

Critical involvement of Tcf-1 in expansion of thymocytes

1 reference

12 December 2020

Stabilized beta-catenin extends thymocyte survival by up-regulating Bcl-xL

1 reference

12 December 2020

Identifiers

DOI

10.1093/INTIMM/DXN051

1 reference

17 August 2017

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17 August 2017

1 reference