Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia (Q36914650)

17 August 2017

Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia (English)

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17 August 2017

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S H Oram

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17 August 2017

J Thoms

2

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17 August 2017

J I Sive

3

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17 August 2017

F J Calero-Nieto

4

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17 August 2017

S J Kinston

5

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17 August 2017

J Schütte

6

1 reference

17 August 2017

K Knezevic

7

1 reference

17 August 2017

R B Lock

8

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17 August 2017

J E Pimanda

9

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17 August 2017

B Göttgens

10

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17 August 2017

10 January 2013

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17 August 2017

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17 August 2017

27

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6

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17 August 2017

1348-1357

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Creative Commons Attribution 3.0 Unported

17 August 2017

start time

10 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/leu.2013.2

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cites work

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29 September 2017

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Integrative genomics identifies LMO1 as a neuroblastoma oncogene

29 September 2017

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29 September 2017

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A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients

29 September 2017

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Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.

29 September 2017

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The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal

29 September 2017

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BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

29 September 2017

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The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

29 September 2017

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The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.

29 September 2017

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Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

29 September 2017

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

29 September 2017

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Fli1, Elf1, and Ets1 regulate the proximal promoter of the LMO2 gene in endothelial cells.

29 September 2017

1 reference

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Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice

29 September 2017

1 reference

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Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies

29 September 2017

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Gene expression profiling in T-cell acute lymphoblastic leukemia

29 September 2017

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

29 September 2017

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

29 September 2017

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Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice

29 September 2017

1 reference

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The LMO1 and LDB1 proteins interact in human T cell acute leukaemia with the chromosomal translocation t(11;14)(p15;q11)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3

29 September 2017

1 reference

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An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice

29 September 2017

1 reference

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Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL

29 September 2017

1 reference

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Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

29 September 2017

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The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15

29 September 2017

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lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

29 September 2017

1 reference

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The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein

29 September 2017

1 reference

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An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs

29 September 2017

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Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression

29 September 2017

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The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

29 September 2017

1 reference

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Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

Oncogenic transcription factors in the human acute leukemias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

SCL, the gene implicated in human T-cell leukaemia, is oncogenic in a murine T-lymphocyte cell line.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

Segmental and developmental regulation of a presumptive T-cell oncogene in the central nervous system

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

Candidate gene association analysis of acute lymphoblastic leukemia identifies new susceptibility locus at 11p15 (LMO1).

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677138

The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23302769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of Lmo1 as part of a Hox-dependent regulatory network for hindbrain patterning

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23302769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23302769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LEU.2013.2

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23302769

1 reference