Prion proteins: a biological role beyond prion diseases (Q36895918)

16 August 2017

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title

Prion proteins: a biological role beyond prion diseases (English)

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16 August 2017

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Hu W

1

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16 August 2017

Rosenberg RN

series ordinal

2

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16 August 2017

Stüve O

series ordinal

3

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16 August 2017

language of work or name

English

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publication date

1 August 2007

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Acta Neurologica Scandinavica

16 August 2017

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16 August 2017

116

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16 August 2017

2

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16 August 2017

75-82

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Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

16 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

The cellular prion protein binds copper in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein selectively binds copper(II) ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Cellular isoform of the scrapie agent protein participates in lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

The expression and potential function of cellular prion protein in human lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

The normal cellular prion protein is strongly expressed by myeloid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Molecular biology of prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Scrapie prion protein contains a phosphatidylinositol glycolipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Diagnosis of human prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Biopsy diagnosis of Creutzfeldt-Jakob disease by western blot: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Pathogenesis of prion diseases: current status and future outlook

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Two-dimensional mapping of three phenotype-associated isoforms of the prion protein in sporadic Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: different prion proteins determined by a DNA polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

A 'unified theory' of prion propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Familial and sporadic fatal insomnia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Barriers to autopsy: Creutzfeldt-Jakob disease in New York state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

How to improve the clinical diagnosis of Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Emerging pharmacotherapies for Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Efficient and specific down-regulation of prion protein expression by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Specific inhibition of pathological prion protein accumulation by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Molecular genetics of human prion diseases in Germany.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

The 129 codon polymorphism of the prion protein gene influences earlier cognitive performance in Down syndrome subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein gene codon 129 modulates clinical course of neurological Wilson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

The prion gene is associated with human long-term memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Polymorphism of the prion protein is associated with cognitive impairment in the elderly: the EVA study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Early cognitive decline is associated with prion protein codon 129 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

PrP knock-out and PrP transgenic mice in prion research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Genomic characterization of the human prion protein (PrP) gene locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

In situ hybridization analysis of PrP mRNA in human CNS tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

PrP-dependent cell adhesion in N2a neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Neuroprotective functions of prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prions prevent neuronal cell-line death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein protects human neurons against Bax-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Breaking the mitochondrial barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Cellular prion protein neuroprotective function: implications in prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

A human prion protein peptide (PrP59–91) protects against copper neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Cellular prion protein transduces neuroprotective signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Signal transduction through prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Mossy fibre reorganization in the hippocampus of prion protein null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Cellular prion protein ablation impairs behavior as a function of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

PrP gene dosage and long term potentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Female-specific neuroprotection against transient brain ischemia observed in mice devoid of prion protein is abolished by ectopic expression of prion protein-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein expression by mouse dendritic cells is restricted to the nonplasmacytoid subsets and correlates with the maturation state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Prion protein is a component of the multimolecular signaling complex involved in T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

PrP expression in B lymphocytes is not required for prion neuroinvasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

Altered circadian activity rhythms and sleep in mice devoid of prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0404.2007.00868.X

10.1111/J.1600-0404.2007.00868.X

21 January 2018

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DOI

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16 August 2017

1 reference