Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells. (Q36884678)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26769970%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells (English)

1 reference

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5 March 2020

4

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5 March 2020

author name string

Hongran Wang

1

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5 March 2020

Xiaohong Wang

2

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5 March 2020

Xueping Xu

3

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5 March 2020

Austin J Cooney

5

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5 March 2020

language of work or name

English

0 references

publication date

14 January 2016

1 reference

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Journal of Biological Chemistry

5 March 2020

published in

1 reference

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5 March 2020

volume

291

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5 March 2020

issue

16

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5 March 2020

page(s)

8644-8652

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A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages

5 March 2020

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Differential role for transcription factor Oct4 nucleocytoplasmic dynamics in somatic cell reprogramming and self-renewal of embryonic stem cells

29 September 2017

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Specific knockdown of OCT4 in human embryonic stem cells by inducible short hairpin RNA interference.

29 September 2017

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Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures

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The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

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Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells

29 September 2017

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The embryonic function of germ cell nuclear factor is dependent on the DNA binding domain

29 September 2017

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Successful inactivation of endogenous Oct-3/4 and c-mos genes in mouse preimplantation embryos and oocytes using short interfering RNAs

29 September 2017

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Mouse germline restriction of Oct4 expression by germ cell nuclear factor

29 September 2017

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Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation.

29 September 2017

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Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

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Cloning, expression analysis and chromosomal localization of the human nuclear receptor gene GCNF.

29 September 2017

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cDNA cloning of two closely related forms of human germ cell nuclear factor (GCNF).

29 September 2017

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Characterization of the human germ cell nuclear factor gene

29 September 2017

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29 September 2017

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Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells

21 January 2018

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Retinoic acid represses Oct-3/4 gene expression through several retinoic acid-responsive elements located in the promoter-enhancer region

29 September 2017

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Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation

29 September 2017

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RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis

29 September 2017

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Establishment in culture of pluripotential cells from mouse embryos

29 September 2017

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

29 September 2017

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A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4861434

Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage.

29 September 2017

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Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer.

4 September 2018

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The orphan nuclear receptor GCNF recruits DNA methyltransferase for Oct-3/4 silencing

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26769970

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rat and mouse epiblasts differ in their capacity to generate extraembryonic endoderm

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26769970

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M115.694208

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26769970%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26769970%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference