Relevance of soft-tissue penetration by levofloxacin for target site bacterial killing in patients with sepsis (Q36880013)

16 August 2017

Relevance of soft-tissue penetration by levofloxacin for target site bacterial killing in patients with sepsis (English)

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16 August 2017

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M A Zeitlinger

1

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16 August 2017

P Dehghanyar

2

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16 August 2017

B X Mayer

3

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16 August 2017

B S Schenk

4

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16 August 2017

U Neckel

5

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16 August 2017

G Heinz

6

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16 August 2017

A Georgopoulos

7

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16 August 2017

M Müller

8

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16 August 2017

C Joukhadar

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16 August 2017

language of work or name

English

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publication date

1 November 2003

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Antimicrobial Agents and Chemotherapy

16 August 2017

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16 August 2017

47

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16 August 2017

11

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16 August 2017

3548-3553

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Target site concentrations of ciprofloxacin after single intravenous and oral doses

16 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Clinical role of protein binding of quinolones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

In vitro antibacterial activities of DQ-113, a potent quinolone, against clinical isolates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Microdialysis. A novel tool for clinical studies of anti-infective agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Distribution and antimicrobial activity of fosfomycin in the interstitial fluid of human soft tissues.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Pharmacokinetics and pharmacodynamics of fluoroquinolones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

The clinical pharmacokinetics of levofloxacin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

New concepts in the pulmonary disposition of antibiotics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Pharmacokinetics of antibiotics in natural and experimental superficial compartments in animals and humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome. Focus on antibacterial agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

A microdialysis method allowing characterization of intercellular water space in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Mathematical Examination of Dual Individualization Principles (I): Relationships between AUC above MIC and Area under the Inhibitory Curve for Cefmenoxime, Ciprofloxacin, and Tobramycin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Pharmacokinetics of antibiotics in critically ill patients.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Predominant pathogens in hospital infections

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

The ACCP-SCCM consensus conference on sepsis and organ failure.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

In vitro evaluation of the activity of two doses of Levofloxacin alone and in combination with other agents against Pseudomonas aeruginosa.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

In vitro activity of levofloxacin against coagulase-positive and -negative staphylococci

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Is levofloxacin as active as ciprofloxacin against Pseudomonas aeruginosa?

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

In-vitro antibacterial activity of levofloxacin against hospital isolates: a multicentre study.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Choosing an antibiotic on the basis of pharmacodynamics.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Antibiotic penetration in the respiratory tract and implications for the selection of antimicrobial therapy.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=253769

Plasma and tissue pharmacokinetics of cefpirome in patients with sepsis

4 September 2018

1 reference

12 December 2020

Application of microdialysis to clinical pharmacokinetics in humans

1 reference

12 December 2020

In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections

1 reference

12 December 2020

Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomized trial

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12 December 2020

Surgery and intensive care procedures affect the target site distribution of piperacillin

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12 December 2020

A combined in vivo pharmacokinetic-in vitro pharmacodynamic approach to simulate target site pharmacodynamics of antibiotics in humans

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12 December 2020

Pharmacodynamics, a tool for a better use of antibiotics?

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12 December 2020

10.1128/AAC.47.11.3548-3553.2003

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DOI

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16 August 2017

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16 August 2017

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