The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer's disease (Q36872887)

16 August 2017

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title

The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer's disease (English)

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16 August 2017

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Peter J Crouch

1

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Anthony R. White

object named as

Anthony R White

series ordinal

2

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Ashley I. Bush

object named as

Ashley I Bush

series ordinal

3

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language of work or name

English

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publication date

6 July 2007

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16 August 2017

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16 August 2017

274

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16 August 2017

15

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16 August 2017

3775-3783

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A century of Alzheimer's disease

16 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Tau pathology in Alzheimer disease and other tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Neurodegenerative diseases and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Iron and copper metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Zinc-specific autometallographic in vivo selenium methods: tracing of zinc-enriched (ZEN) terminals, ZEN pathways, and pools of zinc ions in a multitude of other ZEN cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

ZnT-3, a putative transporter of zinc into synaptic vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

NMDA receptor activation mediates copper homeostasis in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Changes with age in copper and superoxide dismutase levels in brains of C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Metals and amyloid-beta in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Correlations of regional postmortem enzyme activities with premortem local glucose metabolic rates in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Ceruloplasmin levels in the human superior temporal gyrus in aging and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper, ceruloplasmin and superoxide dismutase in patients with Alzheimer's disease . a case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Proteome-based plasma biomarkers for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Ferritin is a component of the neuritic (senile) plaque in Alzheimer dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

High-field magnetic resonance imaging of brain iron in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Superoxide dismutases and their impact upon human health

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Matrix metalloproteinases: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

A role for zinc in cerebellar synaptic transmission?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

The neurobiology of zinc in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Immersion autometallographic tracing of zinc ions in Alzheimer beta-amyloid plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper binding to the amyloid-beta (Abeta) peptide associated with Alzheimer's disease: folding, coordination geometry, pH dependence, stoichiometry, and affinity of Abeta-(1-28): insights from a range of complementary spectroscopic techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid beta-peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1, -2, and -3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Phosphate analysis and dephosphorylation of modified tau associated with paired helical filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Gene expression profiling in chronic copper overload reveals upregulation of Prnp and App.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Phosphorylation Sites on Tau Identified by Nanoelectrospray Mass Spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05918.X

10.1111/J.1742-4658.2007.05918.X

21 January 2018

Identifiers

DOI

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16 August 2017

1 reference

PubMed ID

17617225