HSP70 binding sites in the tumor suppressor protein p53. (Q36872778)

16 August 2017

HSP70 binding sites in the tumor suppressor protein p53. (English)

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16 August 2017

Fourie AM

1

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16 August 2017

Hupp TR

2

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16 August 2017

Lane DP

3

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16 August 2017

Sang BC

4

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16 August 2017

Barbosa MS

5

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16 August 2017

Sambrook JF

6

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16 August 2017

Gething MJ

7

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16 August 2017

language of work or name

English

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publication date

1 August 1997

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Journal of Biological Chemistry

16 August 2017

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16 August 2017

272

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16 August 2017

31

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16 August 2017

19471-19479

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p53, the cellular gatekeeper for growth and division

16 August 2017

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

p53 function and dysfunction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

T antigen is bound to a host protein in SY40-transformed cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Regulation of the specific DNA binding function of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Demonstration of selective protein complexes of p53 with 73 kDa heat shock cognate protein, but not with 72 kDa heat shock protein in human tumor cells.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Protein folding in the cell

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Heat-shock proteins as molecular chaperones

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Molecular chaperones in cellular protein folding

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Interaction between hsp70 and hsp40, eukaryotic homologues of DnaK and DnaJ, in human cells expressing mutant-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Characterization of mutant p53-hsp72/73 protein-protein complexes by transient expression in monkey COS cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

hsp70 binds specifically to a peptide derived from the highly conserved domain (I) region of p53.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Activation of the cryptic DNA binding function of mutant forms of p53.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Modification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Antibodies against 70-kD heat shock cognate protein inhibit mediated nuclear import of karyophilic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

TP53 tumor suppressor gene: a model for investigating human mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Solution structure of the tetrameric minimum transforming domain of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Tumour suppressor genes and molecular chaperones.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Evidence for allosteric variants of wild-type p53, a tumour suppressor protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Presence of a potent transcription activating sequence in the p53 protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

p53 and Rb: their cellular roles

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Temperature sensitivity for conformation is an intrinsic property of wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

The role of p53 in the normal control of cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Hsc70-binding peptides selected from a phage display peptide library that resemble organellar targeting sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

Peptide-binding specificity of the molecular chaperone BiP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19471

21 January 2018

Identifiers

DOI

10.1074/JBC.272.31.19471

1 reference

16 August 2017

1 reference