Deamidation in human lens betaB2-crystallin destabilizes the dimer (Q36869359)

16 August 2017

Deamidation in human lens betaB2-crystallin destabilizes the dimer (English)

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16 August 2017

Kirsten J Lampi

1

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16 August 2017

Kencee K Amyx

series ordinal

2

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16 August 2017

Petra Ahmann

series ordinal

3

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16 August 2017

Eric A Steel

series ordinal

4

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16 August 2017

language of work or name

English

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publication date

1 March 2006

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16 August 2017

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16 August 2017

45

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16 August 2017

10

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16 August 2017

3146-3153

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Unfolding crystallins: the destabilizing role of a beta-hairpin cysteine in betaB2-crystallin by simulation and experiment

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Contributions of hydrophobic domain interface interactions to the folding and stability of human gammaD-crystallin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Laser light-scattering evidence for an altered association of beta B1-crystallin deamidated in the connecting peptide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Energetics of domain-domain interactions and entropy driven association of beta-crystallins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Crystal structure of truncated human βB1‐crystallin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Unfolding of human lens recombinant betaB2- and gammaC-crystallins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Deamidation in human gamma S-crystallin from cataractous lenses is influenced by surface exposure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Lens crystallins and their microbial homologs: structure, stability, and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Spectroscopic analysis of lens recombinant betaB2- and gammaC-crystallin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Close packing of an oligomeric eye lens beta-crystallin induces loss of symmetry and ordering of sequence extensions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

29 September 2017

Global data on blindness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

X-ray analysis of beta B2-crystallin and evolution of oligomeric lens proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Identification of post-translational modifications by blind search of mass spectra.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Mutational analysis of hydrophobic domain interactions in gamma B-crystallin from bovine eye lens

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

The conformation of T4 bacteriophage dihydrofolate reductase from circular dichroism.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

27 June 2018

The vertebrate eye lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Interdomain side-chain interactions in human gammaD crystallin influencing folding and stability

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

The stability of human acidic beta-crystallin oligomers and hetero-oligomers

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Human beta-crystallins modified by backbone cleavage, deamidation and oxidation are prone to associate

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Deamidation, but not truncation, decreases the urea stability of a lens structural protein, betaB1-crystallin

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Resistance of human betaB2-crystallin to in vivo modification.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Folding of bacterial luciferase involves a non-native heterodimeric intermediate in equilibrium with the native enzyme and the unfolded subunits.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533042

Human lens beta-crystallin solubility

4 September 2018

1 reference

12 December 2020

Increased deamidation of asparagine during human senile cataractogenesis

1 reference

12 December 2020

Deamidation of Human βB1 Alters the Elongated Structure of the Dimer

1 reference

12 December 2020

Binding of destabilized betaB2-crystallin mutants to alpha-crystallin: the role of a folding intermediate

1 reference

12 December 2020

Quaternary interactions in eye lens beta-crystallins: basic and acidic subunits of beta-crystallins favor heterologous association

1 reference

12 December 2020

High resolution structure of an oligomeric eye lens beta-crystallin. Loops, arches, linkers and interfaces in beta B2 dimer compared to a monomeric gamma-crystallin

1 reference

12 December 2020

Structural studies on beta H-crystallin from bovine eye lens

1 reference

12 December 2020

Age-dependent deamidation of alpha B-crystallin

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12 December 2020

Formation and crystallization of the eye lens heterodimer beta B2-beta B3-crystallin

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12 December 2020

Modifications of the water-insoluble human lens alpha-crystallins

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12 December 2020

Disulfide bond formation of cysteine-37 and cysteine-66 of beta B2 crystallin during cataractogenesis of the human lens

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12 December 2020

Deamidation of specific glutamine residues from alpha-A crystallin during aging of the human lens

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12 December 2020

Deamidation and disulfide bonding in human lens gamma-crystallins

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12 December 2020

Folding and self-assembly of the domains of betaB2-crystallin from rat eye lens

1 reference

12 December 2020

Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm

1 reference

12 December 2020

Interaction and biophysical properties of human lens Q155* betaB2-crystallin mutant

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12 December 2020

Identifiers

DOI

10.1021/BI052051K

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16 August 2017

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16 August 2017

PubMed publication ID

16519509

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