Antibiotic tissue penetration and its relevance: impact of tissue penetration on infection response (Q36863646)

16 August 2017

1 reference

title

Antibiotic tissue penetration and its relevance: impact of tissue penetration on infection response (English)

1 reference

16 August 2017

1 reference

10.1128/AAC.35.10.1953

https://api.crossref.org/works/10.1128/AAC.35.10.1953

17 November 2022

author name string

D. E. Nix

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1759813

17 November 2022

S. D. Goodwin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1759813

17 November 2022

C. A. Peloquin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1759813

17 November 2022

D. L. Rotella

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1759813

17 November 2022

J. J. Schentag

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1759813

17 November 2022

language of work or name

English

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publication date

1 October 1991

1 reference

16 August 2017

7

1 reference

full work available at URL

inferred from page(s)

https://europepmc.org/articles/PMC245307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1759813

https://europepmc.org/articles/PMC245307?pdf=render

17 November 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1759813

https://journals.asm.org/doi/pdf/10.1128/AAC.35.10.1953

17 November 2022

1 reference

Crossref

DOI

10.1128/AAC.35.10.1953

https://api.crossref.org/works/10.1128/AAC.35.10.1953

Antimicrobial Agents and Chemotherapy

17 November 2022

published in

1 reference

16 August 2017

35

1 reference

16 August 2017

10

1 reference

16 August 2017

1953-1959

1 reference

Tracer experiments with I131 labeled human serum albumin: distribution and degradation studies

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Rate of methicillin penetration into normal heart valve and experimental endocarditis lesions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Antibiotic entry into human polymorphonuclear leukocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Current practices in antimicrobial dosing

29 September 2017

1 reference

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Antibiotic assays in muscle: are conventional tissue levels misleading as indicator of the antibacterial activity?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Influence of protein binding of antibiotics on serum pharmacokinetics and extravascular penetration: clinically useful concepts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Comparison Study of the Kinetics of Ceftizoxime Penetration into Extravascular Spaces with Known Surface Area/Volume Ratio In Vitro and In Vivo in Rabbits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Suction skin blister, skin window, and skin chamber techniques to determine extravascular passage of cefotaxime in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

In vitro activity and human pharmacokinetics of teicoplanin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Clinical significance of protein binding of the penicillins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Serum Protein Binding of the Aminoglycoside Antibiotics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Interaction of Intraleukocytic Bacteria and Antibiotics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Interaction of purulent material with antibiotics used to treat Pseudomonas infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Influence of binding on the pharmacologic activity of antibiotics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Performance of a diffusional clearance model for beta-lactam antimicrobial agents as influenced by extravascular protein binding and interstitial fluid kinetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nephrotoxicities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Contrasts between phagocyte antibiotic uptake and subsequent intracellular bactericidal activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Vancomycin enhancement of experimental tobramycin nephrotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

The clinical relevance of protein binding and tissue concentrations in antimicrobial therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Continuous versus intermittent administration of ceftazidime in experimental Klebsiella pneumoniae pneumonia in normal and leukopenic rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

The use of antibiotic serum levels to predict concentrations in tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Tissue penetration of antibiotics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Role of pharmacokinetics in the outcome of infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

The quinolones: an overview and comparative appraisal of their pharmacokinetics and pharmacodynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Clinical pharmacokinetics of the newer antibacterial 4-quinolones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Effect of protein binding on drug penetration into blister fluid

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Resistance occurring after fluoroquinolone therapy of experimental Pseudomonas aeruginosa peritonitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Tissue penetration of ciprofloxacin after single and multiple doses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Liposome-encapsulated-amikacin therapy of Mycobacterium avium complex infection in beige mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Clinical significance of antibiotic tissue penetration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Liposome-encapsulated-gentamicin therapy of Mycobacterium avium complex infection in beige mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Antibiotic tissue penetration and its relevance: models of tissue penetration and their meaning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Effects of Divalent Cations on Binding of Aminoglycoside Antibiotics to Human Serum Proteins and to Bacteria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Cephalosporin and aminoglycoside concentrations in peritoneal capsular fluid in rabbits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Evaluation of three newer methods for investigating protein interactions of penicillin G

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Prediction of cefazolin penetration in high- and low-protein-containing extravascular fluid: new method for performing simultaneous studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Ascitic fluid cephalosporin concentrations: influence of protein binding and serum pharmacokinetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Penetration of antimicrobials into tissue culture cells and leucocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Theory and practical impact of binding of antimicrobials to serum proteins and tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Tissue cage experiments with beta-lactam antibiotics in rabbits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Studies on the pharmacokinetics of cefoxitin, cefuroxime, cephaloridine and cephalothin using subcutaneous tissue cages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Significance of Serum Protein and Tissue Binding of Antimicrobial Agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

What is interstitial fluid? Biochemical and physiological analysis of fluid obtained from tissue cages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

A review of the penetration of antibiotics into CSF and its clinical significance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Protein binding of antimicrobials: clinical pharmacokinetic and therapeutic implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Inhibition of the Antibacterial Activity of Gentamicin by Urine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

A method for studying antibiotic concentrations in inflammatory exudate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Potential impact of quantitative susceptibility tests on the design of aminoglycoside dosing regimens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Endogenous accumulation products and serum protein binding in uremia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Simultaneous comparison of three methods for assessing ceftazidime penetration into extravascular fluid

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Pharmacokinetics and tissue penetration of ciprofloxacin

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Integration of Selected Pharmacologic and Microbiologic Properties of Three New -Lactam Antibiotics: A Hypothesis for Rational Comparison

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Effect of protein binding on simulated intravascular and extravascular kinetics of cefotaxime in an in vitro model

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Effect of protein binding on cefmenoxime steady-state kinetics in critical patients

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Clinical pharmacology of the new penicillins. 1. The importance of serum protein binding in determining antimicrobial activity and concentration in serum.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Penetration of antibiotics into fibrin loci in vivo. 3. Intermittent vs. continuous infusion and the effect of probenecid.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

A method for measurement of antibiotics in human interstitial fluid.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Antibiotic accumulation in human polymorphonuclear leucocytes and lymphocytes.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Dual individualization of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Effect of ciprofloxacin on intracellular organisms: in-vitro and in-vivo studies.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Evaluation of intravenous ciprofloxacin in patients with nosocomial lower respiratory tract infections. Impact of plasma concentrations, organism, minimum inhibitory concentration, and clinical condition on bacterial eradication.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Protein binding of drugs in uremic and normal serum: the role of endogenous binding inhibitors

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Simultaneous antibiotic levels in "breakthrough" gram-negative rod bacteremia

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Gentamicin tissue accumulation and nephrotoxic reactions

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

The Influence of Dosage Regimen on Experimental Gentamicin Nephrotoxicity: Dissociation of Peak Serum Levels from Renal Failure

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Failure of a once-daily regimen of cefonicid for treatment of endocarditis due to Staphylococcus aureus.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Role for Dual Individualization with Cefmenoxime

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

General principles of antibiotic tissue penetration

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Influence of LY146032 on human polymorphonuclear leucocytes in vitro.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

Renal parenchymal accumulation of aminoglycoside antibiotics in rats

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=245307

In vivo postantibiotic effect in a thigh infection in neutropenic mice

20 October 2018

1 reference

12 December 2020

Serum and tissue levels of teicoplanin during cardiac surgery: the effect of a high dose regimen

1 reference

12 December 2020

Evaluation of methods to determine protein-binding of drugs. Equilibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration

1 reference

12 December 2020

Gentamicin disposition and tissue accumulation on multiple dosing

1 reference

12 December 2020

Effect of the ratio of surface area to volume on the penetration of antibiotics in to extravascular spaces in an in vitro model

1 reference

12 December 2020

Mechanism of aminoglycoside-induced lysosomal phospholipidosis: in vitro and in vivo studies with gentamicin and amikacin

1 reference

12 December 2020

Effect of protein binding on antibiotic activity in vivo

1 reference

12 December 2020

Protein binding of beta-lactams: the effects on activity and pharmacology particularly tissue penetration. I

1 reference

12 December 2020

Protein binding of beta-lactams: the effects on activity and pharmacology particularly tissue penetration. II. Studies in man

1 reference

12 December 2020

A problem in the interpretation of beta-lactam antibiotic levels in tissues

1 reference

12 December 2020

Intracellular penetration and antimicrobial activity of antibiotics

1 reference

12 December 2020

The pharmacokinetics and tissue penetration of norfloxacin

1 reference

12 December 2020

Alteration of drug-protein binding in renal disease

1 reference

12 December 2020

Integration of pharmacokinetics and pharmacodynamics of methicillin in curative treatment of experimental endocarditis

1 reference

12 December 2020

Dual individualization: antibiotic dosage calculation from the integration of in-vitro pharmacodynamics and in-vivo pharmacokinetics

1 reference

12 December 2020

The relevance of pharmacokinetics to in-vitro models: protein binding--does it matter?

1 reference

12 December 2020

A rapid, modified ultrafiltration method for determining serum protein binding and its application to new penicillins

1 reference

12 December 2020

Effect of the concentrations of magnesium and calcium on the in-vitro susceptibility of Pseudomonas aeruginosa to gentamicin

1 reference

12 December 2020

Effect of protein binding on levels of ampicillin and cloxacillin in synovial fluid

1 reference

12 December 2020

Cloxacillin and nafcillin: serum binding and its relationship to antibacterial effect in mice

1 reference

12 December 2020

Experience in monitoring gentamicin therapy during treatment of serious gram-negative sepsis

1 reference

12 December 2020

Recovery of cortical phospholipidosis and necrosis after acute gentamicin loading in rats

1 reference

12 December 2020

Influence of surface area/volume ratio on the kinetics of antibiotics in different tissues and tissue fluids

1 reference

12 December 2020

Importance of drug-protein interactions and protein concentrations for antibiotic levels in serum and tissue fluid

1 reference

12 December 2020

Correlation of pharmacokinetic indices with therapeutic outcome in patients receiving aminoglycosides

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.35.10.1953

1 reference

16 August 2017

1 reference

16 August 2017

1 reference

PMCID

245307