Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics (Q36853653)

16 August 2017

Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics (English)

1 reference

16 August 2017

1 reference

Antonis Voutetakis

1

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16 August 2017

Marc R Kok

2

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16 August 2017

Changyu Zheng

3

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16 August 2017

Ioannis Bossis

4

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16 August 2017

Jianghua Wang

5

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16 August 2017

Ana P Cotrim

6

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16 August 2017

Natanya Marracino

7

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16 August 2017

Corinne M Goldsmith

8

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16 August 2017

John A Chiorini

9

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16 August 2017

Y Peng Loh

10

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16 August 2017

Lynnette K Nieman

11

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16 August 2017

Bruce J Baum

12

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16 August 2017

language of work or name

English

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publication date

20 February 2004

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16 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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16 August 2017

101

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16 August 2017

9

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16 August 2017

3053-3058

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Genetic fate of recombinant adeno-associated virus vector genomes in muscle

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Kidney-targeted naked DNA transfer by retrograde renal vein injection in rats.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Gene transfer to salivary glands

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Recombinant adeno-associated virus serotype 2 vectors mediate stable interleukin 10 secretion from salivary glands into the bloodstream

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

A death in the laboratory: the politics of the Gelsinger aftermath

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Optimization of the helper-dependent adenovirus system for production and potency in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Polarized secretion of transgene products from salivary glands in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Selective extraction of polyoma DNA from infected mouse cell cultures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Salivary glands: a paradigm for diversity of gland development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

High-efficiency transfer of the T cell co-stimulatory molecule B7-2 to lymphoid cells using high-titer recombinant adeno-associated virus vectors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Evidence for the systemic delivery of a transgene product from salivary glands

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Developing a convenient large animal model for gene transfer to salivary glands in vivo

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Long-term erythropoietin gene expression from transduced cells in bioisolator devices

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Distribution and toxicity resulting from adenoviral vector administration to a single salivary gland in adult rats

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Mechanisms leading to sustained reversion of beta-thalassemia in mice by doxycycline-controlled Epo delivery from muscles

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Scalable purification of adeno-associated virus type 2, 4, or 5 using ion-exchange chromatography

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Evaluation of salivary gland acinar and ductal cell-specific promoters in vivo with recombinant adenoviral vectors

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectors

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Hydroxychloroquine enhances the endocrine secretion of adenovirus-directed growth hormone from rat submandibular glands in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Cationic liposome-mediated gene transfer to rat salivary epithelial cells in vitro and in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

4 September 2018

Gene therapy on trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Improvement of erythropoiesis in beta-thalassemic mice by continuous erythropoietin delivery from muscle

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Erythropoietin is produced by tubular cells of the rat kidney.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=365743

4 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400136101

Cell renewal in the organs and tissues of the nongrowing adult mouse

21 January 2018

1 reference

12 December 2020

The streaming submandibular gland

1 reference

12 December 2020

Glycosylation at specific sites of erythropoietin is essential for biosynthesis, secretion, and biological function

1 reference

12 December 2020

Proliferative activity by cell type in the developing rat parotid gland

1 reference

12 December 2020

1 reference

12 December 2020

The endocrine secretion of mammalian digestive enzymes by exocrine glands

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0400136101

1 reference

16 August 2017

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16 August 2017

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