CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases (Q36846646)

16 August 2017

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title

CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases (English)

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16 August 2017

10

Klaus Busam

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James P. Allison

12

object named as

James P Allison

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Sylvia Adams

object named as

Sylvia Adams

8

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Jedd D. Wolchok

14

object named as

Jedd D Wolchok

1 reference

16 August 2017

13

Achim Jungbluth

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16 August 2017

11

Lloyd J Old

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16 August 2017

9

Nina Bhardwaj

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16 August 2017

Jianda Yuan

1

1 reference

16 August 2017

Brian Ginsberg

2

1 reference

16 August 2017

David Page

3

1 reference

16 August 2017

Yanyun Li

4

1 reference

16 August 2017

Teresa Rasalan

5

1 reference

16 August 2017

Humilidad F Gallardo

6

1 reference

16 August 2017

Yinyan Xu

7

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16 August 2017

Klaus Busam

10

1 reference

16 August 2017

5 April 2011

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Cancer Immunology, Immunotherapy

16 August 2017

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16 August 2017

60

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16 August 2017

1137-1146

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16 August 2017

8

1 reference

https://scigraph.springernature.com/pub.10.1007/s00262-011-1011-9

16 August 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit

29 September 2017

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29 September 2017

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Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

29 September 2017

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Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant

29 September 2017

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29 September 2017

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29 September 2017

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Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma

29 September 2017

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Live attenuated lentivirus infection elicits polyfunctional simian immunodeficiency virus Gag-specific CD8+ T cells with reduced apoptotic susceptibility in rhesus macaques that control virus replication after challenge with pathogenic SIVmac239.

29 September 2017

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29 September 2017

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Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

29 September 2017

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29 September 2017

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CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

29 September 2017

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Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade

29 September 2017

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29 September 2017

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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

29 September 2017

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Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

29 September 2017

1 reference

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29 September 2017

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

29 September 2017

1 reference

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Optimization and validation of a robust human T-cell culture method for monitoring phenotypic and polyfunctional antigen-specific CD4 and CD8 T-cell responses

29 September 2017

1 reference

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CTLA-4-Mediated inhibition of early events of T cell proliferation.

27 June 2018

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Melan-A-specific cytotoxic T cells are associated with tumor regression and autoimmunity following treatment with anti-CTLA-4.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMATRIX vaccine in patients with advanced malignant melanoma

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

Safety and immunogenicity of tyrosinase DNA vaccines in patients with melanoma.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

Enhanced viral and tumor immunity with intranodal injection of canary pox viruses expressing the melanoma antigen, gp100.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654853

Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21465316

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differentiation antigens of melanocytes and melanoma: analysis of melanosome and cell surface markers of human pigmented cells with monoclonal antibodies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21465316

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumor antigen expression in melanoma varies according to antigen and stage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21465316

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00262-011-1011-9

1 reference

16 August 2017

1 reference

16 August 2017

1 reference