Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. (Q36843713)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18579797%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development (English)

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9 January 2020

3

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9 January 2020

author name string

Fukun Guo

1

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9 January 2020

Jose A Cancelas

2

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9 January 2020

David A Williams

4

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9 January 2020

Yi Zheng

5

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9 January 2020

language of work or name

English

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publication date

25 June 2008

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9 January 2020

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9 January 2020

volume

112

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9 January 2020

issue

5

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9 January 2020

page(s)

1767-1775

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Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.

9 January 2020

cites work

1 reference

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Involvement of Rho family GTPases in p19Arf- and p53-mediated proliferation of primary mouse embryonic fibroblasts

29 September 2017

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Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.

29 September 2017

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Rho GTPases in cell biology

29 September 2017

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Regulation of Rho family GTPases by cell-cell and cell-matrix adhesion.

29 September 2017

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VAV proteins as signal integrators for multi-subunit immune-recognition receptors

29 September 2017

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Dbl family guanine nucleotide exchange factors

29 September 2017

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Deficiency of small GTPase Rac2 affects T cell activation

29 September 2017

1 reference

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Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt.

29 September 2017

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Lymphoid development from stem cells and the common lymphocyte progenitors

29 September 2017

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Phosphatidylinositol 3-kinase, Cdc42, and Rac1 act downstream of Ras in integrin-dependent neurite outgrowth in N1E-115 neuroblastoma cells

29 September 2017

1 reference

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Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

29 September 2017

1 reference

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Lymphoid development from hematopoietic stem cells

29 September 2017

1 reference

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Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518885

Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518885

Rho GTPases and the actin cytoskeleton

29 September 2017

1 reference

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Rho GTPases and signaling networks

29 September 2017

1 reference

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Characterization of RAC3, a novel member of the Rho family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518885

Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518885

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518885

The murine rac1 gene: cDNA cloning, tissue distribution and regulated expression of rac1 mRNA by disassembly of actin microfilaments

29 September 2017

1 reference

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

29 September 2017

1 reference

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Cell type-specific functions of Rho GTPases revealed by gene targeting in mice.

29 September 2017

1 reference

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Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518885

Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2518885

Lymphoproliferative defects in mice lacking the expression of neurofibromin: functional and biochemical consequences of Nf1 deficiency in T-cell development and function

5 September 2018

1 reference

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The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection.

5 September 2018

1 reference

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Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

5 September 2018

1 reference

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Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in TH 1 responses

5 September 2018

1 reference

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Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

4 December 2018

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12 December 2020

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

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12 December 2020

Requirement of Rac1 and Rac2 Expression by Mature Dendritic Cells for T Cell Priming

1 reference

12 December 2020

A member of the ras gene superfamily is expressed specifically in T, B and myeloid hemopoietic cells

1 reference

12 December 2020

Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase

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12 December 2020

Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization

1 reference

12 December 2020

Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways

1 reference

12 December 2020

Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

1 reference

12 December 2020

Control of pre-T cell proliferation and differentiation by the GTPase Rac-1

1 reference

12 December 2020

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

1 reference

12 December 2020

10.1182/BLOOD-2008-01-132068

Identifiers

DOI

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9 January 2020

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9 January 2020

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