The etiopathogenesis of Parkinson disease and suggestions for future research. Part II. (Q36812817)

16 August 2017

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title

The etiopathogenesis of Parkinson disease and suggestions for future research. Part II. (English)

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16 August 2017

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17

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16 August 2017

Irene Litvan

1

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Richard H Myers

Richard H Myers

9

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Glenda Halliday

Glenda Halliday

14

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Anthony Lang

Anthony E Lang

13

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Thomas Gasser

3

Thomas Gasser

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16 August 2017

7

John Hardy

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16 August 2017

19

Christopher G Goetz

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16 August 2017

11

Mark Hallett

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Marie-Françoise Chesselet

16 August 2017

2

Marie-Francoise Chesselet

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16 August 2017

15

Walter Rocca

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16 August 2017

16

Charles Duyckaerts

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16 August 2017

18

Yoav Ben-Shlomo

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16 August 2017

William John Langston

12

William J Langston

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16 August 2017

6

Theo Hagg

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16 August 2017

20

Eldad Melamed

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16 August 2017

Donato A Di Monte

4

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16 August 2017

Davis Parker

5

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16 August 2017

Peter Jenner

8

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16 August 2017

Donald Price

10

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16 August 2017

1 May 2007

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Journal of Neuropathology & Experimental Neurology

16 August 2017

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16 August 2017

66

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16 August 2017

5

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16 August 2017

329-336

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

16 August 2017

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

The biochemistry of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Complete genomic screen in Parkinson disease: evidence for multiple genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Genome-wide scan for Parkinson's disease: the GenePD Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

A susceptibility gene for late-onset idiopathic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

High-resolution whole-genome association study of Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Multiple regions of alpha-synuclein are associated with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Association of an extended haplotype in the tau gene with progressive supranuclear palsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Expression of normal sequence pathogenic proteins for neurodegenerative disease contributes to disease risk: 'permissive templating' as a general mechanism underlying neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Parkinson's disease: mechanisms and models

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Genetic mouse models of parkinsonism: strengths and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Risk factors for dopaminergic neuron loss in human alpha-synuclein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Drosophila models of neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

The free radical hypothesis in idiopathic parkinsonism: evidence against it

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

The possible role of iron in the etiopathology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Mapping of a gene for Parkinson's disease to chromosome 4q21-q23

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Role of oxidative stress in paraquat-induced dopaminergic cell degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Glutathione in Parkinson's disease: a link between oxidative stress and mitochondrial damage?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammation and alleviated by minocycline administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Molecular pathophysiology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Proteasome inhibition and Parkinson's disease modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Lack of nigrostriatal pathology in a rat model of proteasome inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Use of cytoplasmic hybrid cell lines for elucidating the role of mitochondrial dysfunction in Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Genome-wide linkage analysis and evidence of gene-by-gene interactions in a sample of 362 multiplex Parkinson disease families

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2FNEN.0B013E318053716A

10.1097/NEN.0B013E318053716A

21 January 2018

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DOI

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16 August 2017

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