ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo (Q36802449)

16 August 2017

ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo (English)

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16 August 2017

Denis M Schewe

1

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16 August 2017

Julio A Aguirre-Ghiso

series ordinal

2

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16 August 2017

language of work or name

English

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publication date

23 July 2008

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Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

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16 August 2017

105

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16 August 2017

30

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16 August 2017

10519-10524

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describes a project that uses

16 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2492459/fullTextXML

inferred from PubMed Central ID database lookup

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Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

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Green fluorescent protein tagging of extracellular signal-regulated kinase and p38 pathways reveals novel dynamics of pathway activation during primary and metastatic growth

29 September 2017

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ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK).

29 September 2017

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Requirement of the p38 mitogen-activated protein kinase signalling pathway for the induction of the 78 kDa glucose-regulated protein/immunoglobulin heavy-chain binding protein by azetidine stress: activating transcription factor 6 as a target [...]

29 September 2017

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

29 September 2017

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Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.

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Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

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Rheb activation of mTOR and S6K1 signaling.

27 June 2018

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Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

5 September 2018

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Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck

5 September 2018

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p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6.

5 September 2018

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Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer

5 September 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0800939105

TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum

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Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo

21 January 2018

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12 December 2020

Changes in malignant phenotype of a human carcinoma conditioned by growth environment

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12 December 2020

Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients

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12 December 2020

Prognostic value of immunohistochemically identifiable tumor cells in lymph nodes of patients with completely resected esophageal cancer

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12 December 2020

Cell stress and MKK6b-mediated p38 MAP kinase activation inhibit tumor necrosis factor-induced IkappaB phosphorylation and NF-kappaB activation

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12 December 2020

Circulating tumor cells in patients with breast cancer dormancy

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12 December 2020

An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas

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12 December 2020

ER stress signaling by regulated proteolysis of ATF6

1 reference

12 December 2020

Multiple Gene Expression Classifiers from Different Array Platforms Predict Poor Prognosis of Colorectal Cancer

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0800939105

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16 August 2017

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16 August 2017

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