Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2 (Q36792519)

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scientific article published on 12 April 2016

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English	Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2	scientific article published on 12 April 2016

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scholarly article

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Europe PubMed Central

16 August 2017

Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2 (English)

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Europe PubMed Central

16 August 2017

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9

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Johan Auwerx

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Thomas Lüscher

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Thomas F Lüscher

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Stephan Winnik

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Urs Eriksson

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Christine Lohmann

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Christine Lohmann

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Lambertus J van Tits

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Lambertus J van Tits

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Lisa Pasterk

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16 August 2017

Natacha Calatayud

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Natacha Calatayud

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16 August 2017

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Daniel S Gaul

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Giovanni Siciliani

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Julien Weber

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Christian M Matter

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16 August 2017

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12 April 2016

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Basic Research in Cardiology

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16 August 2017

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Creative Commons Attribution 4.0 International

12 April 2016

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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4829622/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1007/s00395-016-0552-7

0 references

Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia

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Oxidative stress and ROS metabolism via down-regulation of sirtuin 3 expression in Cmah-null mice affect hearing loss

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Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

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Sirt3 protects cortical neurons against oxidative stress via regulating mitochondrial Ca2+ and mitochondrial biogenesis

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Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity

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Sirtuins: guardians of mammalian healthspan

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Regulation of skeletal muscle oxidative capacity and muscle mass by SIRT3.

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Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development

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The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

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Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

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High glucose induced alteration of SIRTs in endothelial cells causes rapid aging in a p300 and FOXO regulated pathway

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29 September 2017

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

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SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status

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Sirtuins as regulators of metabolism and healthspan

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Lifetime risks of cardiovascular disease

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Sirtuins mediate mammalian metabolic responses to nutrient availability

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SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

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The SirT3 divining rod points to oxidative stress

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Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

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29 September 2017

Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation.

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Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

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29 September 2017

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

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29 September 2017

Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction

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29 September 2017

DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome

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29 September 2017

Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest

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29 September 2017

Mammalian sirtuins: biological insights and disease relevance

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The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesis

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Genetic variation in healthy oldest-old

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29 September 2017

Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

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29 September 2017

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

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29 September 2017

SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression

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Inactivity of nitric oxide synthase gene in the atherosclerotic human carotid artery

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Mitochondrial dysfunction in atherosclerosis.

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Endothelial nitric oxide synthase: host defense enzyme of the endothelium?

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A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

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Oxidative stress and vascular disease

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Caloric restriction and aging in primates: Relevance to humans and possible CR mimetics

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Skeletal muscle Sirt3 expression and mitochondrial respiration are regulated by a prenatal low-protein diet

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SIRT3 deficiency impairs mitochondrial and contractile function in the heart.

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Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans

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SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage

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Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.

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c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress

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CCAAT/enhancer-binding protein (C/EBP) beta is acetylated at multiple lysines: acetylation of C/EBPbeta at lysine 39 modulates its ability to activate transcription

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12 December 2020

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00395-016-0552-7

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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