Randomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final results (Q36764997)

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scientific article published on 22 January 2013

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English	Randomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final results	scientific article published on 22 January 2013

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22 February 2020

Randomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final results (English)

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22 February 2020

radiation therapy

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pancreatic cancer

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based on heuristic

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4

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22 February 2020

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Timothy M Pawlik

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22 February 2020

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Raj J Shah

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22 February 2020

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Joseph M Herman

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Aaron T Wild

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Hao Wang

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Kenneth J Chang

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Gretchen E Taylor

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Ross C Donehower

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Mark A Ziegler

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Hongyan Cai

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Dionne T Savage

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Marcia I Canto

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Jason Klapman

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Tony Reid

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Sarah E Hoffe

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Alexander Rosemurgy

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Christopher L Wolfgang

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Daniel A Laheru

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22 January 2013

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22 February 2020

Journal of Clinical Oncology

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22 February 2020

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22 February 2020

886-894

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22 February 2020

Evaluation of predictive variables in locally advanced pancreatic adenocarcinoma patients receiving definitive chemoradiation.

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Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies

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29 September 2017

EUS or percutaneously guided intratumoral TNFerade biologic with 5-fluorouracil and radiotherapy for first-line treatment of locally advanced pancreatic cancer: a phase I/II study

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Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial

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Neoadjuvant therapy may lead to successful surgical resection and improved survival in patients with borderline resectable pancreatic cancer

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Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages

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A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities

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TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors

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Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results of

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Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response

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Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma

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Tumor necrosis factor-alpha and Fas activate complementary Fas-associated death domain-dependent pathways that enhance apoptosis induced by gamma-irradiation.

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Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer

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Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study

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Cytokine levels and systemic toxicity in patients undergoing isolated limb perfusion with high-dose tumor necrosis factor, interferon gamma, and melphalan

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Treatment of locally unresectable cancer of the stomach and pancreas: a randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil--an Eastern Cooperative Oncology Group study

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12 December 2020

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Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver

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Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. Gastrointestinal Tumor Study Group

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12 December 2020

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Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study

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Identifiers

10.1200/JCO.2012.44.7516

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22 February 2020

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22 February 2020

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22 February 2020

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